Navigation Links
Saved by junk DNA
Date:5/28/2009

Leuven, Belgium - VIB researchers linked to K.U.Leuven and Harvard University show that stretches of DNA previously believed to be useless 'junk' DNA play a vital role in the evolution of our genome. They found that unstable pieces of junk DNA help tuning gene activity and enable organisms to quickly adapt to changes in their environments. The results will be published in the reputed scientific Journal Science.

Junk DNA

'Most people do not realize that all our genes only comprise about 3% of the total human genome. The rest is basically one large black box', says Kevin Verstrepen, heading the research team. 'Why do we have this DNA, what is it doing?'.

Scientists used to believe that most of the DNA outside of genes, the so-called non-coding DNA, is useless trash that has sneaked into our genome and refuses to leave. One commonly known example of such 'junk DNA' are the so-called tandem repeats, short stretches of DNA that are repeated head-to-tail. 'At first sight, it may seem unlikely that this stutter-DNA has any biological function', says Marcelo Vinces, one of the lead authors on the paper. 'On the other hand, it seems hard to believe that nature would foster such a wasteful system'.

Unstable repeats

The international team of scientists found that stretches of tandem repeats influence the activity of neighboring genes. The repeats determine how tightly the local DNA is wrapped around specific proteins called 'nucleosomes', and this packaging structure dictates to what extent genes can be activated. Interestingly, tandem repeats are very unstable - the number of repeats changes frequently when the DNA is copied. These changes affect the local DNA packaging, which in turn alters gene activity. In this way, unstable junk DNA allows fast shifts in gene activity, which may allow organisms to tune the activity of genes to match changing environments -a vital principle for survival in the endless evolutio
'/>"/>

Contact: Sooike Stoops
sooike.stoops@vib.be
329-244-6611
VIB (the Flanders Institute for Biotechnology)
Source:Eurekalert

Page: 1 2

Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/3/2014)... 2, 2014   Marvin Test Solutions , ... solutions for military, aerospace, and manufacturing organizations, today ... successful TS-900 PXI semiconductor test platform . ... high-end systems to customers at a fraction of ... traditional ATE. "Our semiconductor customers ...
(Date:11/21/2014)... Nov. 20, 2014 Strict laws against distracted ... piloting the North American and European automotive sector towards ... gesture recognition systems that are intuitive and able to ... the industry. New analysis from Frost ... Market in Europe and ...
(Date:11/18/2014)... 2014   News Highlights: ... develop The Partners Data Lake, an agile data ... Lake will allow researcher and clinicians to explore ... the lives of patients , The Partners ... across the Partners system, breaking down physical barriers ...
Breaking Biology News(10 mins):Marvin Test Solutions Brings New Capabilities to PXI-Based Semiconductor Test with TS-960 2Marvin Test Solutions Brings New Capabilities to PXI-Based Semiconductor Test with TS-960 3Gesture Recognition Intensifies with the Rise of In-car Smartphone Integration, Says Frost & Sullivan 2Gesture Recognition Intensifies with the Rise of In-car Smartphone Integration, Says Frost & Sullivan 3Gesture Recognition Intensifies with the Rise of In-car Smartphone Integration, Says Frost & Sullivan 4Partners HealthCare and EMC Unite to Solve Health Care's Toughest Challenges Using Big Data 2Partners HealthCare and EMC Unite to Solve Health Care's Toughest Challenges Using Big Data 3Partners HealthCare and EMC Unite to Solve Health Care's Toughest Challenges Using Big Data 4Partners HealthCare and EMC Unite to Solve Health Care's Toughest Challenges Using Big Data 5
... Center for Behavioral Neuroscience at Georgia State University ... grant to form a Research Coordination Network focused ... field can be the foundation for integrating molecular ... deep insights into the molecular processes behind social ...
... Capital Chairman Sir Michael Moritz, KBE, and his wife, Harriet Heyman, ... new endowment with a $60 million contribution to ensure the ... gift is being made in recognition of the critical role ... largest endowed program for PhD students in the history of ...
... 24, 2013  Array BioPharma Inc. (Nasdaq: ... Officer, Ron Squarer , will speak at ... public is welcome to participate in the conference ... www.arraybiopharma.com .(Logo: http://photos.prnewswire.com/prnh/20121029/LA02195LOGO )Event:NewsMakers in the Biotech ...
Cached Biology News:Georgia State researcher gets $499,209 NSF grant to advance sociogenomics 2UCSF establishes largest endowed program for Ph.D. education in history of UC 2UCSF establishes largest endowed program for Ph.D. education in history of UC 3Array BioPharma to Present at the NewsMakers in the Biotech Industry Conference 2
(Date:12/19/2014)... , Dec. 19, 2014 Naurex Inc., a ... drugs for diseases of the central nervous system, today ... chief executive officer, will present at the 33 rd ... will take place at 3:00 p.m. PST on Tuesday, ... San Francisco, Calif. ...
(Date:12/19/2014)... , Dec. 19, 2014 Decision Resources ... will grow at a 12 percent compound annual growth ... of the aging population and the increasing adoption of ... America will also spur demand for dental ... dental implant and periodontal treatments. Other key ...
(Date:12/19/2014)... (PRWEB) December 18, 2014 Today, ... locate its pilot production facility and future company ... and produce innovative new materials that safely and ... not only because of its historic, strong support ... efforts to attract leading edge, technology-based companies such ...
(Date:12/19/2014)... Reports from CDC show approximately ... one or more chronic health conditions - including cardiovascular ... some of these diseases, but may not eliminate the ... While implanted nerve stimulation devices today offer relief, they ... can induce side effects. , To eliminate the ...
Breaking Biology Technology:Naurex to Present at 33rd Annual J.P. Morgan Healthcare Conference 2Latin American Dental Biomaterial Market Will Expand at a 12 Percent Annual Growth Rate Through 2023 2Latin American Dental Biomaterial Market Will Expand at a 12 Percent Annual Growth Rate Through 2023 3Technology Company TiFiber™ to Establish Production Facility in Fort Smith, Arkansas with Support from Local Investors 2Technology Company TiFiber™ to Establish Production Facility in Fort Smith, Arkansas with Support from Local Investors 3Technology Company TiFiber™ to Establish Production Facility in Fort Smith, Arkansas with Support from Local Investors 4Draper Wins GSK Funding for Smaller, Smarter Implantable Devices 2
... Entest BioMedical Inc. (OTC Bulletin Board: ENTB) announced today the ... of chronic obstructive pulmonary disease (COPD), a condition that affects ... in more than 120,000 deaths per year. The application ... system to stop tissue inflammation. , "The importance ...
... ... of leading RTLS solution providers, Sonitor,s Ultrasound identification (USID) technology is now including ... in 5 minutes per location. , ... Bothell, WA (PRWEB) November 18, 2009 -- One of the many ...
... ... Using iSirona Technology , ... Panama City, Fla. (PRWEB) November 18, 2009 --iSirona®, an innovative ... of iSirona,s DeviceConX at University Hospitals Geneva Medical Center and University Hospitals Geauga ...
Cached Biology Technology:Entest BioMedical Files 3rd Patent Application for COPD Stem Cell Treatment 2Hand-washing Compliance, Computer Auto Log-on/ Log-off and Patient Fall-detection are Enabled by Real Time Location System (RTLS) with Sub-room Location Accuracy 2Hand-washing Compliance, Computer Auto Log-on/ Log-off and Patient Fall-detection are Enabled by Real Time Location System (RTLS) with Sub-room Location Accuracy 3Hand-washing Compliance, Computer Auto Log-on/ Log-off and Patient Fall-detection are Enabled by Real Time Location System (RTLS) with Sub-room Location Accuracy 4iSirona Announces Go-live at University Hospitals in Cleveland 2iSirona Announces Go-live at University Hospitals in Cleveland 3
... SpeedVac™ Concentrators set the standard for sample concentration ... with large chamber uses a combination of centrifugal ... in a single run. , SC210A comes equipped ... for long lasting chemical compatibility ...
Digital display of time, vacuum and temperature , Dual vacuum control of ramping rate and ultimate level , Comes complete with RH40-12 (40 x 1.5 ml) Rotor and (2) Glass Condensation Flasks. ...
... series of vacuum concentrators/centrifugal evaporators offers a ... to rapid and safe concentration of heat-labile ... with oil-free or high vacuum pumps, a ... selection of rotors (eliminating sample loss by ...
... George Paxinos Affiliation: School of Psychology, The University ... Affiliation: Curtin University of Technology, Perth, Australia This ... of the rat brain. It is a ... revison and extension of the compact 3rd edition. ...
Biology Products: