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Samtools CRAMS in support for improved compression formats
Date:8/15/2014

and integrate more cleanly with other tools.

"Samtools 1.0 embeds CRAM into genomic data analysis pipelines and removes the need for additional processing," says Dr John Marshall, from the Sanger Institute. "This development paves the way for widespread uptake of this highly efficient file format in genomic research and will lead to lower storage costs."

The significant savings in storage that can be achieved are due to incorporating data compression techniques developed jointly by the Sanger Institute and the EMBL-European Bioinformatics Institute.

"It has been exciting to work on implementing CRAM into Samtools," says James Bonfield, at the Sanger Institute. "The great flexibility of CRAM has allowed a number of new compression techniques to be incorporated, which when combined with Samtools 1.0 will help to future-proof genomic data storage and analysis."


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Contact: Mark Thomson
mt9@sanger.ac.uk
44-122-371-0865
Wellcome Trust Sanger Institute
Source:Eurekalert

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