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Same gene that stunts infants' growth also makes them grow too big
Date:5/27/2012

ey to a successful end.

"Our findings leave no doubt that this set of symptoms is a true syndrome and not just a figment of my imagination," said Vilain.

"What makes this special for me is finally being able to unravel what caused the life-threatening disease in the two patients I saw nearly 20 years ago," he added. "As a clinical scientist, the reward for successful research is uncovering new clues that allow us to help patients feel better by improving their medical care."

The IMAGe mutation's ability to miniaturize organisms and halt growth could offer intriguing clinical benefits, he noted.

"Our next effort will focus on manipulating the mutation's strong influence on growth to shrink tumors in the adrenal glands and other internal organs," explained Vilain.


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Contact: Elaine Schmidt
eschmidt@mednet.ucla.edu
310-794-2272
University of California - Los Angeles Health Sciences
Source:Eurekalert

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