Navigation Links
Same gene protects from 1 disease, opens door to another
Date:9/2/2007

CORVALLIS, Ore. Botanists at Oregon State University have discovered that a single plant gene can cause resistance to one disease at the same time it produces susceptibility to a different disease the first time this unusual phenomenon has ever been observed in plants.

The finding, published this week in Proceedings of the National Academy of Sciences, may help scientists better understand the pathways that genetic disease resistance can take. Plant diseases are a multi-billion dollar problem in agriculture, and scientists for decades have been trying to develop new varieties of plants with resistance to one disease or another.

The research also explains why an epidemic of Victoria blight, a fungal disease, occurred in the United States in the 1940s. The Pc-2 gene in a widely-planted, imported variety of oats provided good resistance to oat rust, which is a costly crop disease but the same gene also caused susceptibility to Victoria blight, and its use had to be discontinued as a result.

The blight fungus makes a toxin that causes disease in susceptible plants that is, only plants that carry this gene, said Jennifer Lorang, an OSU research associate. But it also turned out that the same gene can provide disease protection. This is very unusual, and should provide insight into genetic influences on disease resistance and susceptibility.

Most work that has been done on plant diseases is focused on disease resistance, the researchers said, and less has been done on the genetic basis for disease susceptibility.

Among other things, the study suggests that plants bred for resistance to one disease may inadvertently be changed in ways that make them susceptible to a different disease. It also indicates that the physiological basis for disease resistance and susceptibility may have some similarities.

The actual plant used to identify these genetic pathways was Arabidopsis, a small plant in the mustard family, which is frequently used for genetic research. The scientists put the Pc-2-like gene in Arabidopsis, which has a similar function in oats, and were able to determine that it causes disease susceptibility, although it looks like a resistance gene.


'/>"/>

Contact: Tom Wolpert
wolpertt@science.oregonstate.edu
541-737-5293
Oregon State University
Source:Eurekalert

Related biology news :

1. Bound for destruction: Ubiquitination protects against improper Notch signaling
2. Experiments provide proof of how traveling in groups protects insects
3. Experiments provide proof of how traveling in groups protects insects
4. Gene Vaccine Protects Mice Against Development Of Her2/neu Breast Cancer
5. Substance protects resilient staph bacteria
6. Molecule that usually protects infection-fighting cells may cause plaque deposits inside arteries
7. NSAID drug protects against intestinal tumors in mice, despite poor diet and gene losses
8. Mutation in clams protects against paralytic shellfish poisoning but raises human health risk
9. Excess liver gene protects against high-fat diet
10. New vaccine protects more effectively against tuberculosis
11. New type of rejection blocker protects kidneys after transplant
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/5/2017)... KEY FINDINGS The global market ... CAGR of 25.76% during the forecast period of 2017-2025. ... for the growth of the stem cell market. ... MARKET INSIGHTS The global stem cell market is segmented ... The stem cell market of the product is segmented ...
(Date:3/30/2017)... The research team of The Hong Kong Polytechnic University (PolyU) ... ground breaking 3D fingerprint minutiae recovery and matching technology, pushing contactless ... use in identification, crime investigation, immigration control, security of access and ... ... A research team led by Dr Ajay Kumar ...
(Date:3/27/2017)... , March 27, 2017  Catholic Health Services ... Management Systems Society (HIMSS) Analytics for achieving Stage ... Model sm . In addition, CHS previously earned ... hospitals using an electronic medical record (EMR). ... high level of EMR usage in an outpatient ...
Breaking Biology News(10 mins):
(Date:5/16/2017)... May 16, 2017 Telehealth has long ... and something that has been kept completely separate ... But according to   Logicalis Healthcare Solutions , ... IT solutions and managed services provider ( www.us.logicalis.com ... overlooked – interrelationship between telehealth, imaging, and EHR ...
(Date:5/15/2017)... Somerset, N.J. (PRWEB) , ... May 15, 2017 ... ... advanced delivery technologies and development solutions for drugs, biologics and consumer health products, ... biotechnology company focused on rare genetic diseases, to support preclinical and clinical development ...
(Date:5/12/2017)... ARBOR, Mich. , May 12, 2017 ... selected to present at the 36th annual Michigan Growth ... Forum. GreenMark, a Delaware corporation ... be presenting to investors in attendance, including more than ... deliver health benefits to society through biobased targeting technologies. ...
(Date:5/11/2017)... (PRWEB) , ... May 11, 2017 , ... ... rodent neurons both are excellent resources for disease modeling and drug screening. Human ... differentiated into mature neurons for various applications, however, these often contain mixed population ...
Breaking Biology Technology: