Navigation Links
Same gene protects from 1 disease, opens door to another
Date:9/2/2007

CORVALLIS, Ore. Botanists at Oregon State University have discovered that a single plant gene can cause resistance to one disease at the same time it produces susceptibility to a different disease the first time this unusual phenomenon has ever been observed in plants.

The finding, published this week in Proceedings of the National Academy of Sciences, may help scientists better understand the pathways that genetic disease resistance can take. Plant diseases are a multi-billion dollar problem in agriculture, and scientists for decades have been trying to develop new varieties of plants with resistance to one disease or another.

The research also explains why an epidemic of Victoria blight, a fungal disease, occurred in the United States in the 1940s. The Pc-2 gene in a widely-planted, imported variety of oats provided good resistance to oat rust, which is a costly crop disease but the same gene also caused susceptibility to Victoria blight, and its use had to be discontinued as a result.

The blight fungus makes a toxin that causes disease in susceptible plants that is, only plants that carry this gene, said Jennifer Lorang, an OSU research associate. But it also turned out that the same gene can provide disease protection. This is very unusual, and should provide insight into genetic influences on disease resistance and susceptibility.

Most work that has been done on plant diseases is focused on disease resistance, the researchers said, and less has been done on the genetic basis for disease susceptibility.

Among other things, the study suggests that plants bred for resistance to one disease may inadvertently be changed in ways that make them susceptible to a different disease. It also indicates that the physiological basis for disease resistance and susceptibility may have some similarities.

The actual plant used to identify these genetic pathways was Arabidopsis, a small plant in the mustard family, which is frequently used for genetic research. The scientists put the Pc-2-like gene in Arabidopsis, which has a similar function in oats, and were able to determine that it causes disease susceptibility, although it looks like a resistance gene.


'/>"/>

Contact: Tom Wolpert
wolpertt@science.oregonstate.edu
541-737-5293
Oregon State University
Source:Eurekalert

Related biology news :

1. Bound for destruction: Ubiquitination protects against improper Notch signaling
2. Experiments provide proof of how traveling in groups protects insects
3. Experiments provide proof of how traveling in groups protects insects
4. Gene Vaccine Protects Mice Against Development Of Her2/neu Breast Cancer
5. Substance protects resilient staph bacteria
6. Molecule that usually protects infection-fighting cells may cause plaque deposits inside arteries
7. NSAID drug protects against intestinal tumors in mice, despite poor diet and gene losses
8. Mutation in clams protects against paralytic shellfish poisoning but raises human health risk
9. Excess liver gene protects against high-fat diet
10. New vaccine protects more effectively against tuberculosis
11. New type of rejection blocker protects kidneys after transplant
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/23/2017)... ITHACA, N.Y. , June 23, 2017  IBM ... in dairy research, today announced a new collaboration using ... the chances that the global milk supply is impacted ... project, Cornell University has become the newest academic institution ... Chain, a food safety initiative that includes IBM Research, ...
(Date:5/16/2017)... , May 16, 2017  Veratad Technologies, LLC ( ... online age and identity verification solutions, announced today they ... Conference 2017, May 15 thru May 17, 2017, in ... and International Trade Center. Identity impacts ... and in today,s quickly evolving digital world, defining identity ...
(Date:4/24/2017)... , April 24, 2017 ... and partner with  Identity Strategy Partners, LLP (IdSP) ... "With or without President Trump,s March 6, 2017 ... Terrorist Entry , refugee vetting can be instilled with ... resettlement. (Right now, all refugee applications are suspended ...
Breaking Biology News(10 mins):
(Date:10/10/2017)... International research firm Parks Associates announced today that Tom ... 2017 Annual Meeting , October 11 in Scottsdale, Arizona ... and how smart safety and security products impact the competitive landscape. ... Parks Associates: Smart Home Devices: Main Purchase Driver ... "The residential security market has experienced continued growth, and ...
(Date:10/10/2017)... ... October 10, 2017 , ... USDM Life ... for the life sciences and healthcare industries, announces a presentation by Subbu Viswanathan ... The presentation, “Automating GxP Validation for Agile Cloud Platforms,” will present a revolutionary ...
(Date:10/9/2017)...  BioTech Holdings announced today identification and patenting ... stem cell therapy prevents limb loss in animal ... that treatment with ProCell resulted in more than ... to standard bone marrow stem cell administration.  Interestingly, ... of therapeutic effect.  ...
(Date:10/9/2017)... ... October 09, 2017 , ... At its national board meeting ... a professor in Harvard University’s Departments of Physics and Astronomy, has been selected for ... of the winning team for the 2015 Breakthrough Prize in Fundamental physics for the ...
Breaking Biology Technology: