Navigation Links
Saint Louis University researchers discover a way to detect new viruses
Date:6/17/2013

ption is to search for viral genetic material in the body.

There are several methods that use this approach (such as immune based-library screening, mass spectrometry and microarray), but the most useful is next-generation sequencing.

After sorting out the human genetic material from the viral material, the research team compared the viral material against database libraries of known viruses. This identifies any known viruses in the blood.

After this second subtraction, researchers examined the remaining, unidentified material, and sorted out bacteria, phages, and viruses, among other material, based on specific protein signatures that mark each type of microorganism. The discovered, previously unknown viruses remain candidates for further investigation.

Key to the research team's success was the discovery of how to amplify the genetic material in the blood, says study researcher Xiaofeng Fan, M.D., associate professor of internal medicine at Saint Louis University.

In the past, blood serum wasn't used to its full potential because RNA degrades too quickly, leaving too little material to study. The amplification process used by the research team eliminated this problem.

The approach that the research team developed has the potential for immediate application in clinical situations concerning an unknown viral infection, like, for example, the recent outbreak of a SARS-like virus in Saudi Arabia.

In addition to offering a way to discover new viruses and test for known viruses in ill patients, this new technology could provide a valuable approach for those in the biodefense field looking for a way to quickly spot existing bio-threats.

Di Bisceglie says this technique will contribute to our understanding of the many viruses that live in the human body.

"Just as the human microbiome project is chronicling the bacteria that live and co-exist in every person, we also are studying th
'/>"/>

Contact: Carrie Bebermeyer
bebermcl@slu.edu
314-977-8015
Saint Louis University
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. From scourge to saint: E. coli bacteria becomes a factory - to make cheaper, faster pharmaceuticals
2. Vitamin D holds promise in battling a deadly breast cancer, Saint Louis University researchers say
3. In a fight to the finish, Saint Louis University research aims knockout punch at hepatitis B
4. Saint Louis University, University of Toronto biologists help decode turtle genome
5. BP Deepwater Horizon oil spill exacerbated existing environmental problems in Louisiana marshes
6. SMU professor Louis Jacobs honored with prestigious award from Texas science teachers
7. Louisiana Tech University professor earns national honor from Society of American Foresters
8. University of Houston study shows BP oil spill hurt marshes, but recovery possible
9. University of Alberta led research may have discovered how memories are encoded in our brains
10. BGI, University of Helsinki and Wuhan University sign a MOU concerning cooperation on genomics
11. Marshall University study may lead to new treatments for prostate cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/8/2015)... , April 8, 2015  Infinisource, a leading ... services, and Morpho, a leading supplier of biometric ... produce the market,s most advanced biometrically-enabled time clock, ... NXG time clock is setting a bold, new ... data for the small and mid-size employer. When ...
(Date:4/2/2015)... In the current eight ... the strongest competitors, showing outstanding performance in recognition ... is capable of a throughput of 5.000.000 fingerprints ... be ten times faster than most competitors and ...      (Photo: http://photos.prnewswire.com/prnh/20150402/738673-a ) , ...
(Date:4/2/2015)... GOTHENBURG, Sweden , April 2, 2015 ... revenues for Q1 2015 attributed to somewhat higher than ... company in the year-end report 2014 that revenues for ... MSEK that the company reported for Q4 2014. The ... continue to be negative. The complete interim report will ...
Breaking Biology News(10 mins):iSolved Time Clock Offers Unmatched Accuracy due to Morpho Biometrics 2iSolved Time Clock Offers Unmatched Accuracy due to Morpho Biometrics 3DERMALOG AFIS Emerges as Performance Winner in NIST Benchmark Test 2DERMALOG AFIS Emerges as Performance Winner in NIST Benchmark Test 3Fingerprint Cards Revises Revenues for Q1 2015 2
... Since its inception in 2009, the " Contributions to the ... ZooKeys has been playing an important role in ... North America. With a total of 49 publications by 38 ... publications such as Canadian Staphylinidae. Geographic coverage in ...
... University of Granada researchers have designed a guideline for physicians ... disease that makes the subject develop reverse sex, which occurs ... genes. AIS has low prevalence (it only affects one ... of tissues to respond to the action of male hormones. ...
... GSA Bulletin papers published online 11 Jan. 2013 include ... UK, and New Zealand. Multiple locations in the western U.S. ... Guatemala. Papers cover , 1. Holocene record of ... salt, and the fossil forests of Joggins Fossil Cliffs UNESCO ...
Cached Biology News:ZooKeys opens the gates to America's moth diversity 2Study of a rare disease making people look like a woman but having male genitals under study 2GSA Bulletin starts 2013 with 13 new papers published online ahead of print 2GSA Bulletin starts 2013 with 13 new papers published online ahead of print 3GSA Bulletin starts 2013 with 13 new papers published online ahead of print 4GSA Bulletin starts 2013 with 13 new papers published online ahead of print 5GSA Bulletin starts 2013 with 13 new papers published online ahead of print 6GSA Bulletin starts 2013 with 13 new papers published online ahead of print 7GSA Bulletin starts 2013 with 13 new papers published online ahead of print 8GSA Bulletin starts 2013 with 13 new papers published online ahead of print 9GSA Bulletin starts 2013 with 13 new papers published online ahead of print 10GSA Bulletin starts 2013 with 13 new papers published online ahead of print 11
(Date:5/21/2015)... ANGELES , May 21, 2015  CytRx ... and development company specializing in oncology, today announced ... clinical trial with aldoxorubicin for the treatment of ... brain cancer.  The open-label, multisite trial is designed ... aldoxorubicin in patients whose tumors have progressed following ...
(Date:5/21/2015)... King of Prussia, PA (PRWEB) May 21, 2015 ... that Julia O’Neill has joined the firm as senior ... more than 30 years of experience in the management ... the vaccines, biologics, pharmaceutical and chemical industries. , “We’re ... enhance our longstanding capabilities in data analytics,” said Dr. ...
(Date:5/20/2015)... , May 20, 2015  Select Medical ... the Federal Trade Commission granted early termination of ... Improvements Act of 1976, as amended, applicable to ... Acquisition Corporation, a joint venture that Select has ... As previously announced, MJ Acquisition Corporation ...
(Date:5/20/2015)... , May 20, 2015  Haemonetics Corporation (NYSE: ... President & CEO, will present at The Jefferies 2015 ... on June 1 st , 2015 at 8:30am ... Mr. Concannon,s presentation live via webcast at: ... (NYSE: HAE ) is a global healthcare company ...
Breaking Biology Technology:CytRx Reports Positive Updated Phase 2 Aldoxorubicin Clinical Trial Results in Glioblastoma Multiforme (Brain Cancer) 2CytRx Reports Positive Updated Phase 2 Aldoxorubicin Clinical Trial Results in Glioblastoma Multiforme (Brain Cancer) 3CytRx Reports Positive Updated Phase 2 Aldoxorubicin Clinical Trial Results in Glioblastoma Multiforme (Brain Cancer) 4CytRx Reports Positive Updated Phase 2 Aldoxorubicin Clinical Trial Results in Glioblastoma Multiforme (Brain Cancer) 5CytRx Reports Positive Updated Phase 2 Aldoxorubicin Clinical Trial Results in Glioblastoma Multiforme (Brain Cancer) 6CytRx Reports Positive Updated Phase 2 Aldoxorubicin Clinical Trial Results in Glioblastoma Multiforme (Brain Cancer) 7Julia O’Neill Joins Tunnell Consulting’s Operational and Process Improvement Practice 2Select Medical Corporation's Proposed Acquisition of Concentra Inc. through Joint Venture with Welsh Carson Receives Antitrust Clearance 2
... Diana Davis, PhD, Aiguo Zhang, PhD, Chloe Etienne, Ivan Huang,and Michele Malit, Bio-Rad ... , Introduction ... multiplex sandwich immunoassays. , The concentrations of ... quantitated using a calibration or standard curve. More specifically, , ...
... Maria C Jenmalm, 1 Michele Malit, 2 Jim Torrence, 2 , ... 1 Department of Molecular and Clinical Medicine, Division of Paediatrics, , ... Nobel Drive, Hercules, CA 94547 USA , ... Cytokines play a significant role in hematopoiesis, inflammation, and , ...
... , Matthew W. Fields, Section of Microbiology, Cornell ... Introduction , ... organisms by quantitating mRNA levels. The relative abundance of mRNA ... blots, but these , methods depend on accurate ...
Cached Biology Technology:Principles of Curve Fitting for Multiplex Sandwich Immunoassays, Rev B 2Principles of Curve Fitting for Multiplex Sandwich Immunoassays, Rev B 3Principles of Curve Fitting for Multiplex Sandwich Immunoassays, Rev B 4Principles of Curve Fitting for Multiplex Sandwich Immunoassays, Rev B 5Principles of Curve Fitting for Multiplex Sandwich Immunoassays, Rev B 6Principles of Curve Fitting for Multiplex Sandwich Immunoassays, Rev B 7Principles of Curve Fitting for Multiplex Sandwich Immunoassays, Rev B 8Bio-Plex Cytokine Immunoassays and ELISA: Comparison of Two Methodologies in Testing Samples From Asthmatic and Healthy Children, Rev A 2Bio-Plex Cytokine Immunoassays and ELISA: Comparison of Two Methodologies in Testing Samples From Asthmatic and Healthy Children, Rev A 3Bio-Plex Cytokine Immunoassays and ELISA: Comparison of Two Methodologies in Testing Samples From Asthmatic and Healthy Children, Rev A 4Bio-Plex Cytokine Immunoassays and ELISA: Comparison of Two Methodologies in Testing Samples From Asthmatic and Healthy Children, Rev A 5Quantitation of RNA for Hybridization Blots Using the VersaFluor Fluorometer 2
Request Info...
... Kit Components , 25 g Blocking Reagent , ... 10 ml T7 Elution Buffer , 0.2 ml ... , 0.2 ml BLT5615 glycerol stock , 1010 ... Negative Control Lysate , 50 l S-protein HRP Conjugate ...
Attoglow Western Blot Enhancing Kit contains Millennium Enhancer which can significantly boost Western blot signals, and is compatible with other enhancing mechanisms to achieve multiplied enhancing ...
...
Biology Products: