Navigation Links
SRI International receives $100,000 Grand Challenges Explorations grant
Date:5/6/2009

MENLO PARK, Calif. May 6, 2008 SRI International announced today that it has received a US$100,000 Grand Challenges Explorations grant from the Bill & Melinda Gates Foundation. The grant will support an innovative global health research project conducted by Krishna Kodukula, Ph.D., executive director of SRI International's Center for Advanced Drug Research (CADRE) in Shenandoah Valley, Virginia and Amit Galande, Ph.D., associate director of Proteomics and Protein Biochemistry at CADRE, titled "Combating Antibiotic Resistance in Tuberculosis."

SRI's project is one of 81 grants announced by the Gates Foundation in the second funding round of Grand Challenges Explorations, an initiative to help scientists around the world explore bold and largely unproven ways to improve health in developing countries. The grants were provided to scientists in 17 countries on six continents, selected from more than 3,000 proposals received by the Foundation in this highly competitive round of funding.

To receive funding, Kodukula and Galande showed in a two-page application how their idea falls outside current scientific paradigms and might lead to significant advances in global health. SRI's research project will address the problem of antibiotic resistance and the need for broad-spectrum antibiotics. Resistant strains of tuberculosis will initially be screened. Based on those results, the project will be expanded to include other pathogenic bacteria that can lead to the development of the next generation of antibiotics.

Since proteins that are antibiotic targets are prone to mutations that can result in antibiotic resistance, researchers will target non-protein components of cells. Small organic molecule metabolites that are essential for the growth and survival of pathogenic bacteria will be used as targets for antibiotic discovery.

"Antibiotic resistance is a serious public health problem around the world," said Dr. Kodukula. "It can change the course of infections that are treatable and lead to diseases that are difficult to cure. Drug resistant strains of tuberculosis pose a grave threat to global health because treatment options are becoming severely limited."

"The winners of these grants are doing truly exciting and innovative work," said Dr. Tachi Yamada, president of the Gates Foundation's Global Health Program. "I'm optimistic that some of these exploratory projects will lead to life-saving breakthroughs for people in the world's poorest countries."


'/>"/>

Contact: Dina Basin
dina.basin@sri.com
650-859-3845
SRI International
Source:Eurekalert

Related biology news :

1. International team finds key gene that allows plants to survive drought
2. BIO-key(R) International Showcasing Biometric Identification Technology at 2009 RSA Conference
3. Canadian biomedical engineering pioneer receives international award
4. Major international study challenges notions of how genes are controlled in mammals
5. International honor for University of East Anglia ocean researcher
6. Biomedical researchers invited to design experiments for the International Space Station
7. International climate change researchers meet, review latest findings
8. International prize for Nottingham spine research
9. Uvalde Center water research could have national, international applications
10. Anatomical Science International joins Springers publishing program
11. UABs Lisa Guay-Woodford earns top international nephrology prize
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/28/2016)... , April 28, 2016 Infosys ... (NYSE: INFY ), and Samsung SDS, a global ... that will provide end customers with a more secure, fast ...      (Logo: http://photos.prnewswire.com/prnh/20130122/589162 ) , ... but it also plays a fundamental part in enabling and ...
(Date:4/26/2016)... and LONDON , April ... part of EdgeVerve Systems, a product subsidiary of ... today announced a partnership to integrate the Onegini ...      (Logo: http://photos.prnewswire.com/prnh/20151104/283829LOGO ) ... their customers enhanced security to access and transact ...
(Date:4/19/2016)... DUBAI , UAE, April 20, 2016 ... can be implemented as a compact web-based "all-in-one" system ... in the biometric fingerprint reader or the door interface ... requirements of modern access control systems. The minimal dimensions ... the ID readers into the building installations offer considerable ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... 27, 2016   Ginkgo Bioworks , a leading ... was today awarded as one of the World ... world,s most innovative companies. Ginkgo Bioworks is engineering ... real world in the nutrition, health and consumer ... with customers including Fortune 500 companies to design ...
(Date:6/24/2016)... ... , ... Researchers at the Universita Politecnica delle Marche in Ancona combed medical ... mesothelioma. Their findings are the subject of a new article on the Surviving Mesothelioma ... in the blood, lung fluid or tissue of mesothelioma patients that can help point ...
(Date:6/23/2016)... TORONTO , June 23, 2016 /PRNewswire/ - ... Ontario biotechnology company, Propellon ... the development and commercialization of a portfolio of ... cancers. Epigenetic targets such as WDR5 represent an ... contribute significantly in precision medicine for cancer patients. ...
(Date:6/23/2016)... , June 23, 2016  The Prostate Cancer Foundation (PCF) is ... treatments and faster cures for prostate cancer. Members of the Class of 2016 ... countries. Read More About the Class of 2016 PCF ... ... ...
Breaking Biology Technology: