Navigation Links
Rutgers to collaborate in $3.4 million effort to improve prostate cancer identification using MRI
Date:9/22/2009

NEW BRUNSWICK, N.J. Rutgers University and two collaborators have received a $3.4 million research grant to develop tools aimed at improving the identification of prostate cancer using MRI, or magnetic resonance imaging.

The five-year grant, with funding in the first two years from the American Recovery and Reinvestment Act (ARRA) of 2009, was awarded by the National Institutes of Health under an initiative to promote industry and academic partnerships. Rutgers is working with Penn Medicine and Siemens on this pioneering research.

Recent studies by Rutgers and Penn researchers show that powerful, high-resolution MRI technology can reveal cancerous tissue in prostate glands and pinpoint where the tissue is concentrated. Radiologists, however, do not always know whether unusual-looking visual features indicate cancerous growth or benign variations.

"At this time, it's often just a prediction or an educated guess," said Anant Madabhushi, assistant professor of biomedical engineering and Rutgers' principal investigator on the grant. "Before MRI technology is ready for widespread clinical use, the medical profession will have to be confident that it can make readings accurately and consistently."

Each year, there are more than 27,000 deaths from prostate cancer in the United States and 190,000 new cases diagnosed. Diagnosis is based on PSA levels in blood, physical examination and needle biopsies, because current imaging techniques don't distinguish cancerous tissue. MRI has the potential to offer a diagnosis non-invasively and, along with other information, help physicians customize the most effective and least debilitating treatment plan.

Under the research grant, Penn researchers will make magnetic resonance images of prostate glands in cancer patients and prepare tissue samples from those same glands after they are surgically removed in the course of treatment. Rutgers and Siemens researchers will then develop computerized tools that align MRI views with digitized images of tissue slices. These tools will allow investigators to better identify MRI features that reveal cancerous tissue and develop pattern recognition software that will help radiologists make accurate and timely diagnoses.

"This is an immense and complicated task," said Madabhushi, who is also a member of The Cancer Institute of New Jersey. "Our tools will have to account for variations in MRI and tissue image sizes, tissue that was imaged but lost in the process of sectioning, or MRI images shaped differently from tissue sample images due to gland deformation."

Siemens will refine research tools into software packages for scientists to use as they conduct additional studies and develop diagnostic tools and techniques.

While the current research grant focuses on the prostate gland, Madabhushi believes the same tools can be adapted to imaging for breast cancer and other forms of cancers.

ARRA funding is supporting three new postdoctoral research jobs at Rutgers, and one position at Penn to do image collection and management. Research data will become publicly available for further investigations.

Researchers at the University of Pennsylvania School of Medicine include principal investigator Michael Feldman, associate professor of Pathology and Laboratory Medicine and medical director of Pathology Informatics; and co-principal investigators John E Tomaszewski, professor of Pathology and Laboratory Medicine, and Mark Rosen, assistant professor of Radiology.


'/>"/>

Contact: Carl Blesch
cblesch@ur.rutgers.edu
732-932-7084 x616
Rutgers University
Source:Eurekalert  

Related biology news :

1. Rutgers Genetics receives $7.8 million for autism research
2. Rutgers high school outreach gets $3 million boost from NSF
3. Homeland Security awards 2 grants to Rutgers for nuclear threat detection
4. Rutgers scientists research reveals critical knowledge about the nervous system
5. USDA Cooperative Agreement funds mosquito project at Rutgers
6. Raydiance collaborates with Rutgers, MTF to develop innovative tissue processing approaches
7. Better protection for biomedial devices could result from Rutgers-Camden research
8. Rutgers biologist to study worms in Amazon, glaciers
9. $3.2M for Rutgers to apply biology, engineering, physical sciences toward stem cells
10. No helicopter moms among Rutgers mutant mice
11. Rutgers scholar authors definitive biography of reproductive medicine pioneer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Rutgers to collaborate in $3.4 million effort to improve prostate cancer identification using MRI
(Date:3/7/2017)... 2017 Brandwatch , the leading social intelligence company, ... Trust to uncover insights to support its reporting, help direct ... The UK,s leading youth charity will be using Brandwatch Analytics social ... a better understanding of the topics and issues that are a ... ...
(Date:3/2/2017)... -- Summary This report provides all the information ... and activities since 2010. ... Read the full report: http://www.reportlinker.com/p03605615-summary/view-report.html ... provides an in-depth insight into the partnering activity of one ... demand company reports are prepared upon purchase to ensure inclusion ...
(Date:3/2/2017)... , March 2, 2017 Australian stem ... (ASX: CYP), has signed an agreement with the ... the Monash Biomedicine Discovery Institute and Department of Pharmacology ... conduct a further preclinical study to support the use ... of asthma.  Asthma is a chronic, ...
Breaking Biology News(10 mins):
(Date:3/28/2017)... 28, 2017 Biostage, Inc. (Nasdaq: ... bioengineered organ implants to treat cancers and other life-threatening ... that Jim McGorry, CEO of Biostage, will ... panel at the MassBio 2017 Annual Meeting ... in Cambrige, Massachussetts. The 3D Printing and BioEngineering ...
(Date:3/28/2017)... Focus is on the ... to the scientifically intensive operations of companies in ... and industrial. In today,s pre-market research, Stock-Callers.com dedicates attention ... PTLA), OvaScience Inc. (NASDAQ: OVAS), Ocera Therapeutics Inc. ... OCUL ). Learn more about these stocks ...
(Date:3/28/2017)... Triangle Park, NC (PRWEB) , ... March 28, ... ... development company engaged in the development of a new orally administered treatment for ... Advisory Board. , CEO John Didsbury states, “As we seek to uniquely treat ...
(Date:3/27/2017)... Branford, Connecticut (PRWEB) , ... March 27, 2017 ... ... company dedicated to accelerating the fight against cancer, autoimmune disease and more through ... to the single-cell metabolomics and proteomics analysis platform developed in the laboratory ...
Breaking Biology Technology: