Navigation Links
Rutgers laboratory helped to create new HIV drug
Date:6/23/2011

t to changes in HIV.

Clinical trials for Edurant, which included more than 1,300 adults with HIV, indicated that 83 percent of those who were given this anti-AIDS drug for a 48-week period had undetected levels of HIV in their blood at the conclusion of the clinical trial. The new drug can be prescribed as a once-a-day pill to HIV-positive adults who have not received any prior treatment or therapy. Besides being available in the United States, a generic form of the drug will be made available to millions of people in Saharan Africa, India and other developing nations.

"Development of this newest AIDS drug represents a wonderful example of the biomedical power that can be harnessed by scientific collaborations and partnerships between university, government, and private sector research enterprises," said Kenneth J. Breslauer, dean of Life and Health Sciences. "No more satisfying and important outcome can result from university research."

This scientific collaboration began in 1987 when the Rutgers team entered into a partnership with Stephen Hughes, an AIDS researcher at the National Cancer Institute. Both were interested in understanding the molecular structure and function of reverse transcriptase, an essential part of the AIDS virus, not only for its fundamental significance, but also because they believed it would provide guidance for the design of more effective drugs.

Three years later, Arnold reached out to Janssen at the J&J subsidiary, Janssen Pharmaceutica, which had developed promising compounds to prevent reverse transcriptase from being able to create a genetic copy of the AIDS virus. The Rutgers team suggested that crystal structures of the compound created by Janssen, bound to the reverse transcriptase enzyme, could help the company understand and improve its chemical structures and be used to develop more effective AIDS drugs.

They worked together for the next 13 years, during which time Janssen provided $2 million to help fund
'/>"/>

Contact: Robin Lally
rlally@ur.rutgers.edu
732-932-7084 x652
Rutgers University
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Rutgers scholar authors definitive biography of reproductive medicine pioneer
2. Rutgers receives US$10 million to establish Institute for Food, Nutrition and Health
3. Evolution and climate change research advances at Rutgers-Camden
4. Rutgers study finds many consumers ignore food product recalls
5. Rutgers research tackles childhood epilepsy
6. Rutgers-Camden developing enzyme function database
7. Rutgers to collaborate in $3.4 million effort to improve prostate cancer identification using MRI
8. TAXIS Pharmaceuticals licenses novel antimicrobial technology from Rutgers and UMDNJ
9. NSF grant supports Rutgers-Camden program for science majors
10. Rutgers cell biologist pinpoints how RNA viruses copy themselves
11. Rutgers researchers discover secrets of nutritious corn breed that withstands rigors of handling
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/21/2014)... -- Earlier this year Donald Spector , Chairman of ... the most prolific inventors in the world, got a ... to third party agencies. Spector envisioned this technology even ... earliest known patents in this area. Now major technology ... care, elder care and hospital applications. This technology has ...
(Date:11/21/2014)... Nov. 20, 2014   Atmel® Corporation (NASDAQ: ... (MCU) and touch technology solutions, today launched the industry,s ... with the widest V cc range from 1.7V ... and faster I 2 C bus communication speeds, and ... memory making them ideal for consumer, industrial, computer, and ...
(Date:11/18/2014)... Md. , Nov. 17, 2014 The Parenteral ... and U.S. regulatory agencies will speak and at least seven ... Metrics Conference at the Omni Shoreham Hotel in ... pleased once again to have significant support from the regulatory ... Europe in our effort to help ...
Breaking Biology News(10 mins):Patented Biosensor Wearable Technology Provides a More Civilized Method of Quarantine 2Patented Biosensor Wearable Technology Provides a More Civilized Method of Quarantine 3Patented Biosensor Wearable Technology Provides a More Civilized Method of Quarantine 4Atmel Launches Industry's First Wide-V(cc) Low-Power Temperature Sensor Family 2Atmel Launches Industry's First Wide-V(cc) Low-Power Temperature Sensor Family 3Atmel Launches Industry's First Wide-V(cc) Low-Power Temperature Sensor Family 4FDA's Janet Woodcock, EMA's Emer Cooke Headline PDA Quality Metrics Conference 2
... to the results of a recent U.S. study, investigators ... and a potentially life-threatening form of high blood pressure, ... Journal of Infectious Diseases, now available online. , The ... human herpesvirus 8 (HHV-8), also known as the Kaposi's ...
... scientists have coaxed human embryonic stem cells to become ... messages from the brain to the rest of the ... 30, 2005) in the journal Nature Biotechnology by scientists ... provide critical guideposts for scientists trying to repair damaged ...
... containing billions of donor kidney cells will help intensive care ... Medical College of Georgia. , MCG Medical Center has joined ... country to evaluate the efficacy of the renal assist device, ... renal failure and a principal investigator on the study. , ...
Cached Biology News:Association of herpesvirus with lung disorder questioned 2Wisconsin scientists grow critical nerve cells 2Wisconsin scientists grow critical nerve cells 3Bioartificial kidney under study at MCG 2Bioartificial kidney under study at MCG 3
(Date:12/19/2014)... 18, 2014 Ed Bilsky, Ph.D., vice ... Center for Excellence in the Neurosciences (CEN), and professor ... been selected as a member of the prestigious Dana ... neuroscientist from Maine to receive this honor. , ... entirely by the Dana Foundation. Its mission is ...
(Date:12/19/2014)... The empty capsules market is experiencing growth ... technological innovations in the empty capsules market. The ... growth of the empty capsules market. , Get ... of Report , The report will enrich both ... to gauge the pulse of the market which ...
(Date:12/19/2014)...   ISN has released its third annual ... publication series. With data aggregated from over eight ... within its online contractor management platform, ISNetworld, this three-part ... (KPI) statistics. The Contractor ... is available in two industry specific volumes: Oil ...
(Date:12/17/2014)... 16, 2014 “Never say, ‘I ... Universität Marburg’s Department of Physics, advises young women ... newly released SPIE Women in Optics 18-month ... shy to ask questions.” , In the annual ... mathematics) occupations ranging from university professor and laboratory ...
Breaking Biology Technology:UNE's Ed Bilsky Named Member of Dana Alliance for Brain Initiatives 2UNE's Ed Bilsky Named Member of Dana Alliance for Brain Initiatives 3Empty Capsules Market Hit to Reach $1,820 Million by 2019 - New Research Report by MarketsandMarkets 2Empty Capsules Market Hit to Reach $1,820 Million by 2019 - New Research Report by MarketsandMarkets 3Empty Capsules Market Hit to Reach $1,820 Million by 2019 - New Research Report by MarketsandMarkets 4ISN Releases Third Edition of US Contractor Health & Safety Performance Indicators Publication Series 2ISN Releases Third Edition of US Contractor Health & Safety Performance Indicators Publication Series 3Network, Multitask, Persevere: SPIE Women in Optics Planner Subjects Share from Experience 2Network, Multitask, Persevere: SPIE Women in Optics Planner Subjects Share from Experience 3
... , from rat lung, recombinant, , , , , , , ... Pack Size, , , ... , 3335402, 10000 units (5 vials of 2000 ... , Package Inserts/Product , Instructions, , ...
... , , for amplification of 520 kb targets from eukaryotic genomes Cat. ... , Cat. No. 1 681 842 2 x 250 units , ... , , , Description , , , ... PCR buffers for optimal amplification of different DNA fragment lengths: , ...
... , , , , , , , Which ... , , , ... , , , ... <a , ...
Cached Biology Technology:Expand Long Template PCR System 2Find the optimal product for your PCR application 2
... Genomics Solution is a comprehensive suite ... visualization specifically designed to reliably extract ... high-dimensional genomic studies containing thousands of ... memory efficient and will analyze large ...
...
...
Hepatocyte Differentiation Environment...
Biology Products: