Navigation Links
Rutgers-affiliated company receives funding for technology to help choose breast cancer treatments
Date:10/6/2011

type of cancer and predict its severity.

"The problem is, anytime you have a human being in the equation, there's always a question of variability," he said. "What one observer calls aggressive, another may not."

Madabhushi noted that until less than a decade ago, oncologists would be cautious and prescribe both hormone therapy and chemotherapy because the severity was often hard to determine. In 2004, California-based Genomic Health introduced a test that examined gene expression. That test accurately pegged ER+ breast cancers that fell at the low and high ends of the severity scale. Women who scored low could be treated confidently with hormonal therapy alone and forgo chemotherapy.

While the test, known as Oncotype DX, became an important planning resource for oncologists and patients, it remains expensive upwards of $4,000. It also takes two weeks to produce results, which for severe cancers represents a loss of valuable treatment time.

"In 2007, an oncologist at The Cancer Institute of New Jersey, Shridar Ganesan, saw our work on prostate cancer imaging and asked if my lab could apply it to ER-positive breast cancers," said Madabhushi, who is also a member of The Cancer Institute of New Jersey. "So we applied these techniques and started to get very exciting results. We found that our image-based risk score, which we dubbed 'Ibris,' was in agreement with the Oncotype DX score almost 90 percent of the time."

Work funded by the NIH grant, made through the agency's National Institute for Biomedical Imaging and Bioengineering, will establish how well Ibris scores predict long-term patient outcomes. If successful, an Ibris test could deliver results to patients almost immediately and cut costs to patients and their insurers.

The benefits could be even more dramatic in developing countries, claims Madabhushi, where the Oncotype DX cost is prohibitive and sending samples to California can add weeks to the testing
'/>"/>

Contact: Carl Blesch
cblesch@ur.rutgers.edu
732-932-7084 x616
Rutgers University
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Complete Genomics launches, becomes worlds first large-scale human genome sequencing company
2. Lockheed Martin Named Biometrics Company of the Year by Frost and Sullivan
3. Explorations Group Announces Letter of Intent to Acquire Specialty Lighting Company
4. Explorations Group Announces Letter of Intent to Acquire Specialty Lighting Company
5. Lockheed Martin Named Biometrics Company of the Year by Frost and Sullivan
6. Iowa State chemist synthesizes carbohydrates, launches startup company
7. ExcellGene SA first company to offer contract manufacturing in 250 Liter OrbShake bioreactor
8. delSECUR CORPORATION Announces Appointment of the Companys President & CEO
9. Two is not company -- as far as fish are concerned
10. GATC Biotech AG is investing more than 5 million euros in its Constance site to double the companys floor space
11. Company Granted Patent on Apparatus, Systems, and Methods for Gathering and Processing Wireless Biometric and Biomechanical Data
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Rutgers-affiliated company receives funding for technology to help choose breast cancer treatments
(Date:8/29/2014)... such as the prolific bloomer Emiliania huxleyi , ... discovered. The finding contradicts the common view that ... on scarce supplies of thiamine in the ocean to ... about the ocean," says CIFAR Senior Fellow Alexandra ... paper with CIFAR fellows John Archibald (Dalhousie ...
(Date:8/29/2014)... The rise of the Tibetan plateau -- the largest ... important for both its profound effect on climate and ... in GSA Bulletin , Katharine Huntington and colleagues ... -- using modern and fossil snail shells to investigate ... Tibet. , Views range widely on the timing ...
(Date:8/28/2014)... University researchers have identified a handful of bacterial culprits ... Crohn,s disease and ulcerative colitis, using patients, own intestinal ... published Aug. 28 in the journal Cell . ... microbiota, which plays a critical role in the development ... a small number of bacterial species affect a person,s ...
Breaking Biology News(10 mins):Not all phytoplankton in the ocean need to take their vitamins 2Not all phytoplankton in the ocean need to take their vitamins 3Snails tell of the rise and fall of the Tibetan Plateau 2Snails tell of the rise and fall of the Tibetan Plateau 3Snails tell of the rise and fall of the Tibetan Plateau 4Snails tell of the rise and fall of the Tibetan Plateau 5Snails tell of the rise and fall of the Tibetan Plateau 6Snails tell of the rise and fall of the Tibetan Plateau 7Yale study identifies possible bacterial drivers of IBD 2
... research institutes, announced today the launch of three ... in extreme environments. The three selected genomes are ... and emperor penguin, and one altiplano animal: the ... carried out using Next-generation sequencing technologies, which have ...
... Chemical Society (ACS) Weekly PressPac from the Office of ... journals and Chemical & Engineering News .,Please credit ... the source for this information. PressPac Archive: ... IMMEDIATE RELEASE Cousin of the "ice that ...
... as gamma oscillations, for more than 50 years, believing ... for the first time, MIT researchers and colleagues have ... laser light directly onto the brains of mice. ... known as optogenetics, which combines genetic engineering with light ...
Cached Biology News:Genome projects launched for three extreme-environment animals 2Genome projects launched for three extreme-environment animals 3American Chemical Society's Weekly PressPac -- April 22, 2009 2American Chemical Society's Weekly PressPac -- April 22, 2009 3American Chemical Society's Weekly PressPac -- April 22, 2009 4American Chemical Society's Weekly PressPac -- April 22, 2009 5American Chemical Society's Weekly PressPac -- April 22, 2009 6American Chemical Society's Weekly PressPac -- April 22, 2009 7American Chemical Society's Weekly PressPac -- April 22, 2009 8American Chemical Society's Weekly PressPac -- April 22, 2009 9American Chemical Society's Weekly PressPac -- April 22, 2009 10MIT: Making waves in the brain 2
(Date:8/28/2014)... 2014 Sterlitech is proud to announce ... its stable of products . These additional ... and include membrane filters with surface charges. ... demand for our membrane process testing equipment, and correspondingly, ... sheet membranes,” explains Sterlitech President Mark Spatz. “The ...
(Date:8/28/2014)... Vt. (PRWEB) August 28, 2014 ... testing around the world is available from Strategic ... diagnostics companies. “ Industrial Microbiology Market Review, Fourth ... Industrial Market ” (IMMR—4) tracks and compares microbiology ... in North America, Europe and Asia, and forecasts ...
(Date:8/28/2014)... 2014 Whitehouse Laboratories is excited to ... with PTI Inspection Systems that will enable ... the art leak testing method development and validation programs ... available. As part of this agreement, Whitehouse Labs has ... Detection Instrument developed and manufactured by PTI. The ...
(Date:8/27/2014)... August 27, 2014 In 2013, ... Lawrence Livermore National Security LLC (LLNS), ... and deliver a state-of-the-art laser system for the ... Beamlines), under construction in the Czech Republic. , ... laser system, called the " High repetition-rate Advanced ...
Breaking Biology Technology:Sterlitech Corporation Enhances Its Selection of Flat Sheet Membrane Filters 22 Billion Industrial Microbiology Tests Conducted for Product Quality and Safety Worldwide 22 Billion Industrial Microbiology Tests Conducted for Product Quality and Safety Worldwide 3Whitehouse Labs Renews Partnership with PTI Inspection Systems 2Whitehouse Labs Renews Partnership with PTI Inspection Systems 3LLNL Synchs up with ELI Beamlines on Timing System 2LLNL Synchs up with ELI Beamlines on Timing System 3
... APFC ) today announced that it will release ... 5, 2008. John R.,Gibson, Chairman and Chief Executive Officer, ... financial results and outlook of the,Company., The teleconference ... p.m.,PDT. To access the call please dial (973) 582-2852 ...
... VENLO, The Netherlands, July 29 QIAGEN N.V.,(Nasdaq: QGEN ) ... The Webcast will take place at 9:30 a.m. EDT on,Tuesday, August ... Executive Officer, and Roland Sackers, Chief Financial Officer., What: ... results call, When: 9:30 a.m. EDT ...
... a year and a half, cells from pigs are to be ... ... The Lions Clubs of Multiple,District 5M (MD5M) recently declared its ... expedite the,affordable and widespread availability of pig donors of islet tissue ...
Cached Biology Technology:American Pacific to Release Financial Results and Hold Fiscal 2008 Third Quarter Investor Teleconference 2Webcast of QIAGEN N.V.'s (Nasdaq: QGEN) Second Quarter 2008 Financial Results Call Set for August 5 2Spring Point Project Gains Support of Lions Clubs 2Spring Point Project Gains Support of Lions Clubs 3
Allophycocyanin (APC) anti-human CD193 (CCR3, CKR3) 25 tests...
CCNI Antibody...
Rabbit polyclonal to IL23 P19 ( Abpromise for all tested applications). Antigen: Synthetic 16 amino acid peptide from near the amino terminus of human IL23 P19 Entrez Gene ID: 51561 Swiss...
3M Imidazole Solution 125 ml...
Biology Products: