Navigation Links
Rotator cuff tears: Are they all in the family?
Date:4/30/2009

ROSEMONT, ILPeople with relatives who have experienced rotator cuff tears are at increased risk of similar tendon tears themselves, according to a study published in the May 2009 issue of The Journal of Bone and Joint Surgery (JBJS). "This strongly suggests genetic predisposition as a possible cause for rotator cuff disease," said Robert Z. Tashjian, MD, associate professor of orthopaedic surgery, University of Utah School of Medicine Orthopaedic Center in Salt Lake City.

By using the Utah Population Database combined with the University of Utah Health Sciences Data Warehouse numbers, researchers found an increased risk for these tears in family members of patients with rotator cuff tears. The risk extends out and beyond third-cousin relationships (Third cousins are the great-great-grandchildren of one's great-great-grandparents.)

"While we have not determined the exact genetic component," said Dr. Tashjian, "our family history data supports that heredity plays a role in the development of rotator cuff tearing."

This problem usually affects people in their 50s and 60s. It is believed to have both mechanical and environmental influences; however, scientists unclear as to exactly why it occurs, have several theories including:

  • Decreased blood flow leading to tendon dysfunction and tearing
  • Bumping (impingement) of the rotator cuff on the undersurface of the shoulder cap (acromion) when moving the arm
    • This may lead to a slow development of tears due to repetitive micro-trauma over time
  • Age-related degeneration

The potential impact of this research is that it is a springboard for attempting to identify an exact genetic component for this injury. Dr. Tashjian and his colleagues are currently collecting blood samples for DNA analysis of patients with rotator cuff tears, which will be used later for various genetic analyses to determine the exact genetic comp
'/>"/>

Contact: Lauren Pearson
lpearson@aaos.org
American Academy of Orthopaedic Surgeons
Source:Eurekalert

Page: 1 2

Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/11/2014)... DUBLIN , Dec. 09, 2014 Research ... http://photos.prnewswire.com/prnh/20130307/600769 ( http://www.researchandmarkets.com/research/twhjll/biometrics_market ) ... Market in the APAC Region 2015-2019"  report to ... emerging in this market is advances in technology. ... to upgrade biometric solutions to the latest standard ...
(Date:12/10/2014)... 2014 You,ve been here before: you desperately need ... your password, site key or the answer to your secret ... teacher? Today, Hoyos Labs , a ... will finally put an end to the frustration that comes ... . 1U leverages a user,s smartphone to acquire his or ...
(Date:12/10/2014)... , Dec. 08, 2014 Research and Markets ... addition of the "Biometrics Market in Japan ... http://photos.prnewswire.com/prnh/20130307/600769 The ... such as rural banking and upgradation of the ... witnessed in the market. Besides the aforementioned projects, ...
Breaking Biology News(10 mins):Biometrics Market in the APAC Region 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 2The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 3Biometrics Market in Japan 2014-2018: Key Vendors are DDS, Fujitsu, Hitachi and NEC 2
... GAINESVILLE, Fla. Contrary to a widespread assumption, global warming ... malaria control, development and other factors that are at work ... of scientists including two University of Florida researchers in a ... Nature . Scientists and public policy makers have been ...
... New research shows that nearly 1 in 5 cases of ... are caused by not one but multiple strains of the ... of Minnesota Medical School report their findings today in the ... journal published by the American Society for Microbiology. "Koch,s ...
... WASHINGTON -- As part of its most comprehensive study of ... three reports emphasizing why the U.S. should act now to ... adapt to the inevitable impacts of climate change. The ... National Academy of Sciences and National Academy of Engineering, are ...
Cached Biology News:Scientists: Malaria control to overcome disease’s spread as climate warms 2Unexpectedly high rate of multiple strains in fungal infection 2New climate change reports underscore need for action 2New climate change reports underscore need for action 3New climate change reports underscore need for action 4New climate change reports underscore need for action 5
(Date:12/24/2014)... 2014 The report expects global cell ... 2019. It also provides a carefully analyzed data about ... for the market. , Full Copy of Report @ ... global market for cell expansion will keep witnessing growth ... this growth to be driven by rapid technological advancements, ...
(Date:12/24/2014)... LOUIS , Dec. 23, 2014 ... today that the waiting period under the Hart-Scott-Rodino ... the acquisition expired on December 22, 2014, thereby ... review requirement for the acquisition of the Company ... U.S. antitrust clearance satisfies another condition to closing ...
(Date:12/22/2014)... , Dec. 22, 2014 /PRNewswire/ - RepliCel Life Sciences ... medicine company focused on the development of autologous cell ... of the University of Calgary in conjunction with co-authors ... which further validates the company,s ongoing clinical research using ... of pattern baldness. The paper entitled " ...
(Date:12/22/2014)... 22, 2014 ITRA Global, one of ... of commercial real estate, has further expanded its global ... Perth and Brisbane, Western Australia, reports Mylinda Vick, CCIM, ... ITRA Global / ACORPP (Australian Corporate Property and ... company providing property services to a wide range of ...
Breaking Biology Technology:The Cell Expansion Market is Expected to Reach $14.8 billion by 2019 - New Research Report by MarketsandMarkets 2The Cell Expansion Market is Expected to Reach $14.8 billion by 2019 - New Research Report by MarketsandMarkets 3Acquisition of Sigma-Aldrich by Merck KGaA, Darmstadt, Germany, Receives U.S. Antitrust Clearance 2Acquisition of Sigma-Aldrich by Merck KGaA, Darmstadt, Germany, Receives U.S. Antitrust Clearance 3Newly Released Peer-Reviewed Publication Further Validates RepliCel's Use of Dermal Sheath Cup Cells to Treat Pattern Baldness 2Newly Released Peer-Reviewed Publication Further Validates RepliCel's Use of Dermal Sheath Cup Cells to Treat Pattern Baldness 3Newly Released Peer-Reviewed Publication Further Validates RepliCel's Use of Dermal Sheath Cup Cells to Treat Pattern Baldness 4Newly Released Peer-Reviewed Publication Further Validates RepliCel's Use of Dermal Sheath Cup Cells to Treat Pattern Baldness 5ITRA Global Continues International Expansion in Perth and Brisbane, Australia 2
...  bioTheranostics, Inc., a bioMerieux company that develops innovative ... introduced a new product line of high medical ... called PRECIS Precision Medicine by bioTheranostics(SM). Precision medicine, ... diagnosis of primary tumor site and predictive biomarkers ...
... 26, 2012 Lend Lease is pleased to announce ... for the Life Sciences group in the Atlantic Region.  ... will be based out of the Raleigh, NC office, working closely ... in the South Atlantic offices. He will report directly ...
... Jan. 25, 2012  DATATRAK International, Inc. (OTCQX: DATA), ... eClinical solutions for the clinical trials industry, today ... Program, Excel Life Sciences (ELS). Excel Life Sciences ... clinical trial and site management services. ...
Cached Biology Technology:bioTheranostics Launches Precision Medicine Biomarkers for Tumor Pathway Interrogation 2bioTheranostics Launches Precision Medicine Biomarkers for Tumor Pathway Interrogation 3Lend Lease Announces the Appointment of Tom Chapman as Director Operations for the Life Sciences Group in the Atlantic Region 2Excel Life Sciences Joins DATATRAK's Connect Partner Program 2Excel Life Sciences Joins DATATRAK's Connect Partner Program 3
... - Proliferation Marker, prediluted Ki67 antigen ... protein, expressed by proliferating cells in all ... S, G2 and M phase). It is ... are useful in establishing the cell growing ...
Request Info...
Rabbit polyclonal to Aortic Elastin ( Abpromise for all tested applications). entrezGeneID: 2006 SwissProtID: P15502...
Vascular Endothelial Growth Factor C Class: Antibody Product Group: Angiogensis...
Biology Products: