Navigation Links
Role of pro-urokinase in neuronal apoptosis and revascularization after ACI
Date:5/12/2014

Among the drugs used for acute ischemic stroke, recombinant tissue plasminogen activator is widely accepted internationally. In China, urokinase has been widely used for thrombolysis after acute ischemic stroke. Pro-urokinase is the precursor of urokinase. Compared with urokinase, pro-urokinase has greater ability to dissolve thrombus and is safer to use. However, most countries do not recognize urokinase for thrombolytic treatment after acute ischemic stroke, which has not been approved for clinical use. Dr. Wenli Hu and team from Beijing Chao-Yang Hospital, Capital Medical University in China compared the thrombolytic effects of pro-urokinase, recombinant tissue plasminogen activator, and urokinase in a dog model of acute cerebral embolism. They found that jematoxylin and eosin staining showed no hematoma in the infarcted area after thrombolysis with any of the three therapies, and neuronal apoptosis after cerebral infarction was also not attenuated. The results of angiography showed that recanalization after thromboembolism was similar after thrombolysis with pro-urokinase and recombinant tissue plasminogen activator, and that both these drugs were more effective than urokinase. The relevant article was published in the Neural Regeneration Research (Vol. 9, No. 5, 2014).


'/>"/>

Contact: Meng Zhao
eic@nrren.org
86-138-049-98773
Neural Regeneration Research
Source:Eurekalert  

Page: 1

Related biology news :

1. Pretreatment with SSTF prevents hippocampal neuronal apoptosis due to cerebral infarction
2. Impaired cell division leads to neuronal disorder
3. Activating P300 protein contributes to repair of hippocampal neuronal DNA injuries
4. How the Parkin enzyme inhibits neuronal cell death
5. Hippocampal and thalamic neuronal metabolism in a putative rat model of schizophrenia
6. Overexpression of cytoglobin gene increases neuronal hypoxic tolerance
7. Haste and waste on neuronal pathways
8. Different neuronal groups govern right-left alternation when walking
9. Parkinsons disease: Parkin protects from neuronal cell death
10. Neuronal activity induces tau release from healthy neurons
11. Cilia guide neuronal migration in developing brain
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Role of pro-urokinase in neuronal apoptosis and revascularization after ACI
(Date:3/24/2017)... , Mar 24, 2017 Research and Markets ... System Market Analysis & Trends - Industry Forecast to 2025" ... ... grow at a CAGR of around 15.1% over the next decade ... industry report analyzes the market estimates and forecasts for all the ...
(Date:3/22/2017)... , March 21, 2017   Neurotechnology , ... recognition technologies, today announced the release of the ... which provides improved facial recognition using up to ... a single computer. The new version uses deep ... accuracy, and it utilizes a Graphing Processing Unit ...
(Date:3/20/2017)... 2017 At this year,s CeBIT Chancellor Dr. ... DERMALOG. The Chancellor came to the DERMALOG stand together with the Japanese ... CeBIT partner country. At the largest German biometrics company the two government ... and iris recognition as well as DERMALOG´s multi-biometrics system.   ... ...
Breaking Biology News(10 mins):
(Date:6/15/2017)... (PRWEB) , ... June 15, 2017 , ... ... it has secured a Series B round of financing in the amount of ... group of private investors participated in the round. , The Series B funding ...
(Date:6/15/2017)... ... June 15, 2017 , ... angelMD announced ... device startup. Dan Parsley, angelMD’s SVP of Corporate Development, served as the syndicate ... syndicate is part of Saranas’ recently announced $4 million Series B financing round. ...
(Date:6/15/2017)... Conn. (PRWEB) , ... June 15, 2017 , ... ... has published a new guide on how to assemble a lab workstation. The ... terminology. Workstation components include Adam’s Nimbus or Eclipse balance, AVT anti-vibration table, OIML/ASTM ...
(Date:6/14/2017)... Bangkok, Thailand (PRWEB) , ... June 14, 2017 ... ... Thailand Center of Excellence for Life Sciences (TCELS) announces that they’re co-hosting a ... 19-22, 2017. , BIO, the largest biotech industry gathering in the world, ...
Breaking Biology Technology: