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Rockefeller Scientists discover new compound that rids cells of Alzheimer protein debris
Date:3/7/2011

r the effect of SMER28. This research represents a radically different approach to treating Alzheimer's disease, namely boosting a cellular mechanism to enhance the clearance of beta-amyloid, as well as other protein aggregates; and it opens a new therapeutic avenue for the treatment of this and other degenerative diseases.

"Autophagy has been called the cell's equivalent of urban renewal. In that sense, SMER28 functions as a cellular forklift to clear out unwanted debris," said Gerald Weissmann, M.D., Editor-in-Chief of The FASEB Journal. "The Rockefeller group shows that strategies to remove the blight in cells that causes Alzheimer's disease are not only worth pursuing, but so far, appear to be very promising."


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Contact: Cody Mooneyhan
cmooneyhan@faseb.org
301-634-7104
Federation of American Societies for Experimental Biology
Source:Eurekalert

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