Navigation Links
Risk of diabetes in children and adolescents exposed to antipsychotics
Date:9/2/2014

Washington D.C., September 2, 2014 A study published in the September 2014 issue of the Journal of the American Academy of Child and Adolescent Psychiatry found that children and adolescents diagnosed with a psychiatric diagnosis had an increased risk of developing diabetes if they were exposed to antipsychotics.

Using data from the nationwide Danish registers, a group of researchers led by Dr. Ren Ernst Nielsen, Psychiatry, Aalborg University Hospital, Denmark, studied 48,299children and adolescents with psychiatric disorders to document the frequency and possible predictors of type II diabetes, defined by treatment with an oral antidiabetic drug.

The study found that the absolute risk of diabetes in psychiatrically ill youth exposed to antipsychotic medications was approximately 0.72% compared to 0.27% in those not exposed to antipsychotics. Especially female sex and antipsychotic drug exposure increased the risk of developing type II diabetes, while type of psychiatric diagnosis was not related to diabetes development.

Taken together, these data raise further concern about the frequent use of antipsychotics for non-psychotic disorders and off-label conditions, such as disruptive behavior disorders, which should first be treated with non-pharmacologic management options. Moreover, regular cardiometabolic monitoring, including fasting glucose and hemoglobin A1C testing should be integral part of antipsychotic prescribing to children and adolescents.

Dr. Nielsen said of the study, "The use of antipsychotic drug treatment can be necessary for some of the psychiatric disorders diagnosed in children and adolescents. This study underscores the importance of following the current guidelines that antipsychotics should only be used in children and adolescents when other evidence-based and safer treatment options have been exhausted."

The study was a longitudinal register linkage case control study of type II diabetes, defined as prescription of an oral antidiabetic drug, in all child and adolescent hospital-based psychiatric patients diagnosed in Denmark from January 1st 1999 and June 30st 2010. The time period was defined to allow full retrieval of data from all relevant registers.


'/>"/>
Contact: Mary Billingsley
mbillingsley@jaacap.org
202-587-9672
Elsevier
Source:Eurekalert

Related biology news :

1. Diabetes Research Institute develops oxygen-generating biomaterial
2. New study shines light on barriers to diabetes care in NYC Bangladeshi community
3. Commonly used diabetes drug may help to prevent primary liver cancer
4. Approach to diabetes self-management too narrow, study suggests
5. Gut microbiota transplantation may prevent development of diabetes and fatty liver disease
6. From feast to famine: A metabolic switch that may help diabetes treatment
7. Increased fructose consumption may deplete cellular energy in patients with obesity and diabetes
8. Jack Spratt diabetes gene identified
9. Diabetes drug makes brain cells grow
10. Obesity plus low vitamin D may add up to a greater risk of diabetes
11. Joslin researchers gain new understanding of diabetes and kidney disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/22/2016)... Md. , June 22, 2016  The American College ... Trade Show Executive Magazine as one of the ... on May 25-27 at the Bellagio in Las ... on the highest percentage of growth in each of the ... of exhibiting companies and number of attendees. The 2015 ACMG ...
(Date:6/21/2016)... VANCOUVER, British Columbia , June 21, 2016 ... been appointed to the new role of principal ... has been named the director of customer development. ... , NuData,s chief technical officer. The moves reflect ... development teams in response to high customer demand ...
(Date:6/15/2016)... York , June 15, 2016 ... new market report titled "Gesture Recognition Market by Application ... Forecast, 2016 - 2024". According to the report, the  ... 11.60 billion in 2015 and is estimated to ... USD 48.56 billion by 2024.  Increasing ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... , ... June 23, 2016 , ... ... release of its second eBook, “Clinical Trials Patient Recruitment and Retention Tips.” Partnering ... retention in this eBook by providing practical tips, tools, and strategies for clinical ...
(Date:6/23/2016)... , June 23, 2016 Houston Methodist ... the Cy-Fair Sports Association to serve as their ... agreement, Houston Methodist Willowbrook will provide sponsorship support, ... connectivity with association coaches, volunteers, athletes and families. ... the Cy-Fair Sports Association and to bring Houston ...
(Date:6/23/2016)... (PRWEB) , ... June 23, 2016 , ... ... today announced the launch of the Supplyframe Design Lab . Located in ... to explore the future of how hardware projects are designed, built and brought ...
(Date:6/23/2016)... , June 23, 2016 ... Hematology Review, 2016;12(1):22-8 http://doi.org/10.17925/OHR.2016.12.01.22 ... , the peer-reviewed journal from touchONCOLOGY, Andrew ... escalating cost of cancer care is placing an ... result of expensive biologic therapies. With the patents ...
Breaking Biology Technology: