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Risk factors help predict outcomes for children with rare heart condition
Date:9/3/2013

children with a mixed version of the disease that included thickening of the heart walls and enlargement and weakening of the heart and 62 percent for those with a restrictive form of the disease characterized by both a thickening and hardening of the heart walls. Children diagnosed after age one year with hypertrophic cardiomyopathy of unknown cause had the most favorable outcome, a 97 percent rate of transplant-free survival.

Infants and children who had two or more of the following risk factors at HCM diagnosis (depending on the cause of HCM) lower weight or body size, female gender, diagnosis during infancy, congestive heart failure, and abnormal heart function had an increased risk of poor outcomes (death or need for immediate heart transplantation).

These findings are expected to assist clinicians in identifying which children are likely to have the worst outcomes (death or need for immediate heart transplantation) within two years of diagnosis, thereby enabling medical teams, genetic counselors, and family planners to jointly and quickly determine the best treatment approach.


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Contact: NHLBI Communications Office
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NIH/National Heart, Lung and Blood Institute
Source:Eurekalert

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