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Rice scientists divide and conquer
Date:12/28/2009

m, he sees potential for the technology to study the roots of aging itself. Iron is toxic to the body if not managed properly, he said, and since oxidation appears to be central to aging, studies of the process tend to draw a lot of interest.

"Will people age faster because their iron-sulfur cluster assembly is different? To me, the answer is decades out, but it's a very interesting question. How will subtle differences in oxidative stress affect aging?

"It's getting more tantalizing now that there are direct links between defects in iron-sulfur cluster assembly and nuclear genome stability," he said. "It's no longer, 'Oh, mitochondrial oxidative stress is connected somehow to nuclear mutations.' There's evidence that iron-sulfur cluster assembly defects in the mitochondria can be that connection."


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Contact: David Ruth
druth@rice.edu
713-348-6327
Rice University
Source:Eurekalert

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