Navigation Links
Rhythmic genomics -- the yeast metronome and the walk of life
Date:4/7/2009

New genome sequence information from the humble baker's yeast has revealed surprising variation in a set of genes that can be thought of as nature's oldest clock. In a paper published in Genome Research scientists show how ribosomal RNA genes that are essential to all Earth's organisms provide insight into how genomes maintain their integrity on their evolutionary journey.

Ribosomal RNA sequence changes have been ticking away like clockwork for over 3 billion years, maybe even pre-dating the origin of the DNA world itself. However, even the slightest changes in sequence of these genes can be fatal. It is vital to conserve the important genetic 'cogs' to make sure cells function correctly. However, significant changes do occur, contrary to expectation, and yet the yeast somehow still survives.

Furthermore, when two yeasts hybridise the clocks appear to re-set, apparently overwriting each others' rhythm and eliminating unwanted variations on the theme. This provides clues as to how key motifs are conserved and allows us to track the evolutionary history of hybrids.

Steve James, lead researcher at the Institute of Food Research (IFR), said "I have sequenced these genes to selectively identify yeast species for over 15 years and had no idea they would turn out to be so variable."

Rob Davey, computational biologist at the National Collection of Yeast Cultures (NCYC), said "we can use new computer techniques to model the changes mathematically and really get to grips with what orchestrates the variation in these important cell housekeepers."

Ian Roberts, Curator of NCYC, said "Yeasts are everywhere around us in nature and industry. This extra level of detail allows us to resolve important differences between yeasts and gain maximum benefits from their use in food, drink and healthcare."


'/>"/>

Contact: Andrew Chapple
andrew.chapple@bbsrc.ac.uk
44-160-325-1490
Norwich BioScience Institutes
Source:Eurekalert

Page: 1

Related biology news :

1. Biologists identify genes controlling rhythmic plant growth
2. Rhythmic breathing adapts to external beat through brain calculus
3. Major aspergillus genomics supplement published by journal Fungal Genetics and Biology
4. Cancer Genomics Browser gives cancer researchers a powerful new tool
5. Nutrigenomics -- developing personalized diets for disease prevention -- part 2 just published in OMICS
6. Major NSF grant boosts UNH research on hormonal genomics
7. Genomatix gets patent for comparative genomics method
8. Venter, Somerville and Church highlight DOE/JGI genomics of energy and environment meeting
9. Complete Genomics releases proof-of-concept data for its sequencing technology for the first time
10. Comparative genomics reveals molecular evolution of Q fever pathogen
11. Mixing genomics and geography yields insights into life and environment
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/28/2016)... FRANCISCO and BANGALORE, India , ... of EdgeVerve Systems, a product subsidiary of Infosys (NYSE: ... provider, today announced a global partnership that will ... way to use mobile banking and payment services. ... is a key innovation area for financial services, but it ...
(Date:4/15/2016)... April 15, 2016  A new partnership announced ... accurate underwriting decisions in a fraction of the ... priced and high-value life insurance policies to consumers ... With Force Diagnostics, rapid testing (A1C, Cotinine ... readings (blood pressure, weight, pulse, BMI, and activity ...
(Date:3/31/2016)... 2016  Genomics firm Nabsys has completed a financial ... Bready , M.D., who returned to the company in ... leadership team, including Chief Technology Officer, John Oliver ... Nurnberg and Vice President of Software and Informatics, ... Dr. Bready served as CEO of Nabsys from ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... NC (PRWEB) , ... June 27, 2016 , ... ... just published their findings on what they believe could be a new and ... of the new research. Click here to read it now. , ...
(Date:6/27/2016)... N.C. (PRWEB) , ... June 27, 2016 , ... ... commercial operations for Amgen, will join the faculty of the University of ... as adjunct professor of strategy and entrepreneurship at UNC Kenan-Flagler, with a focus ...
(Date:6/24/2016)... , June 24, 2016  Regular discussions on a ... take place between the two entities said Poloz. ... Ottawa , he pointed to the country,s ... the federal government. ... said, "Both institutions have common economic goals, why not sit ...
(Date:6/24/2016)... ... ... Researchers at the Universita Politecnica delle Marche in Ancona combed medical journal ... Their findings are the subject of a new article on the Surviving Mesothelioma website. ... the blood, lung fluid or tissue of mesothelioma patients that can help point doctors ...
Breaking Biology Technology: