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Reviews of microbial gene language published in special issue of Trends in Microbiology
Date:7/14/2009

rse of the molecular biology laboratory and Gene Ontology terms have been instrumental in building a system-wide understanding of the biology of this organism. This type of work allows scientists to use Gene Ontology terms to identify common elements in both plant and animal disease.

One research area that has not received a lot of attention so far is the use of Gene Ontology terms to address viral infection, in part due to fundamental differences between the ways in which viruses and other pathogens infect their hosts. One article in the series outlines how viral pathogens can also be attributed Gene Ontology functions and reveals how scientists are in a position to apply Gene Ontology to the modeling of viral infections.

Brett Tyler, also the PAMGO project leader, remarked: "The research described in this series of articles summarizes both the many dimensions of the microbial world that have been revealed through using Gene Ontology terms as well as the benefits of adopting this shared language for gene function. We strongly encourage the authors of scientific papers to include their own Gene Ontology term assignments when publishing new experimental data about genes and we hope that scientific journals will assist in this process. This practice greatly facilitates the work of biologists interested in looking at organisms across kingdoms, from molecules all the way up to complex biological systems.


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Contact: Barry Whyte
whyte@vbi.vt.edu
540-231-1767
Virginia Tech
Source:Eurekalert

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