Navigation Links
Reviews of microbial gene language published in special issue of Trends in Microbiology
Date:7/14/2009

Blacksburg, Va. -- Ten articles describing how a universal language to describe genes is bringing benefits to the study of the microbial world have been published in a special issue of Trends in Microbiology, co-edited by Virginia Bioinformatics Institute professor Brett Tyler. The Gene Ontology is a powerful language that gives researchers a shared vocabulary to describe disease-related and beneficial interactions between a microbe and its host. By allowing scientists to link experimental results to a computer-readable language, the Gene Ontology provides scientists with an important bridge between specific experiments that characterize gene function and larger-scale, systems biology efforts to provide a global picture of host-microbe interactions.

The Gene Ontology was started in 1998 by a consortium of three databases for the organisms yeast, fruit fly, and mouse. The Plant-Associated Microbe Gene Ontology (PAMGO) Consortium joined the effort in 2004 to focus on microbe-plant associations, which include the many relationships of plants with bacteria, fungi, oomycetes, and nematodes. VBI researcher Trudy Torto-Alalibo, who coordinates the PAMGO project, remarked: "Advances in sequencing technologies have led to a remarkable increase in the number of sequenced microbial genomes. Analysis of these genomes has provided useful information about genes that may be important in microbe-host interactions. However related genes that have a common function can be missed in sequence comparisons if those genes arose from different evolutionary paths. The Gene Ontology offers a way to overcome such limitations and can greatly facilitate the comparison of gene function across the different domains of life."

Candace Collmer of Wells College, who helped launch PAMGO in 2003, noted: "A crucial step at the beginning of the PAMGO project was the realization that plant pathogenesis is only one possible outcome along a continuum of broadly-defined, sym
'/>"/>

Contact: Barry Whyte
whyte@vbi.vt.edu
540-231-1767
Virginia Tech
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Biophysical Reviews makes debut in 2009
2. Sirtris review of sirtuin therapeutics for diseases of aging in Nature Reviews Drug Discovery
3. Exploring standards to advance microbial genomics
4. MIT reels in RNA surprise with microbial ocean catch
5. Illinois Soil Nitrogen Test measures microbial nitrogen
6. Earths highest known microbial systems fueled by volcanic gases
7. Unusual microbial ropes grow slowly in cave lake
8. When under attack, plants can signal microbial friends for help
9. DOE JGI extends the capabilities of the Integrated Microbial Genome System
10. Antimicrobial sutures reduce infections in brain shunt surgery, study finds
11. Barren seafloor teeming with microbial life
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/10/2014)... known as heme enzymes, due to the presence of ... centre of the heme cofactor is an iron (Fe) ... is in an intermediate state called Compound I. The ... this oxidation involves just an oxygen atom (O), or ... implications for understanding oxidative processes within living cells, which ...
(Date:7/10/2014)... HOUSTON (July 10, 2014) New research from ... (UTHealth) shows that It,s Your GameKeep it Real (IYG), ... and promote healthy dating relationships, can significantly reduce dating ... Centers for Disease Control and Prevention, 10 percent of ... and other studies suggest that more than 20 percent ...
(Date:7/10/2014)... Spanish National Cancer Research Centre (CNIO) Macromolecular Crystallography ... a protein called BuD to DNA in order ... Montoya, the researcher who led the study, says ... edit the instructions contained in the genome to ... The study is published in the journal ...
Breaking Biology News(10 mins):Neutron crystallography solves long-standing biological mystery 2Neutron crystallography solves long-standing biological mystery 3It's Your Game ... Keep It Real reduces dating violence among minority youth 2CNIO scientists develop technology to redirect proteins towards specific areas of the genome 2
... Varanus komodoensis ) are known to bite prey and release ... the victims are reported to go into shock before the ... prey are killed by pathogenic bacteria in the dragons, mouths ... of Proceedings of the National Academy of Sciences ...
... active site found in a naturally occurring enzyme, chemists at ... like nature,s most pervasive hydrogen processor. , The researchers describe ... Journal of the American Chemical Society , and posted ... puzzled by nature,s ability to use cheap and plentiful building ...
... million cases of malaria are diagnosed each year mostly ... treat malaria do exist, the demand for new treatments ... have developed a resistance to existing medications. Now, ... have discovered one way to stop malaria parasite growth, ...
Cached Biology News:Komodo even more deadly than thought: Research 2New lead on malaria treatment 2
(Date:7/10/2014)... new study published today in the journal PNAS ... found that time of day and sleep deprivation have ... be crucial when looking at the best time of ... heart disease, and for administering medicines effectively. , Researchers ... Cancer Research, London, investigated the links between sleep deprivation, ...
(Date:7/10/2014)... out for crude 3-D glasses, polarized glasses, and ... basic devices, used to trick the brain into ... rendered obsolete with the introduction of new holography ... TAU doctoral students Yuval Yifat, Michal Eitan, and ... on nanoantennas that could be used for security ...
(Date:1/15/2014)...  Bill Jacobs Automotive, a group of car dealerships headquartered in ... Heartland Blood Center and offering free oil change coupons for ... Saturday, Jan. 18 at the Bill Jacobs Cadillac and Chevrolet ... http://photos.prnewswire.com/prnh/20140115/MN46637 )  The Bill Jacobs Auto ...
(Date:1/15/2014)... OXFORD, England and SAN JOSE, California ... an international biotechnology company developing antibody-drug conjugates for cancer, today ... its Board of Directors. Dr Reynolds has over 20 years, ... Chief Medical Officer at Seattle Genetics. "I am ...
Breaking Biology Technology:Time of day crucial to accurately test for diseases, new research finds 2Projecting a 3-dimensional future 2Projecting a 3-dimensional future 3Join the Bill Jacobs Auto blood drive and receive a free oil change 2Oxford BioTherapeutics Appoints Thomas C Reynolds MD, PhD to its Board of Directors 2Oxford BioTherapeutics Appoints Thomas C Reynolds MD, PhD to its Board of Directors 3
... Purpose , ... of protease inhibitor (PI) and non-nucleoside reverse transcriptase inhibitor (NNRTI) ... of assessing inter-individual and intra-individual metabolism variability. To be of ... to monitor these drugs is fast and easy to perform, ...
... Introduction , ... products are radioactively labeled using either endlabeled primers or ... Successful sequencing results produced by these two labeling methods ... breaks, impurities or high secondary structure can cause DNA ...
... , Researchers and forensic agencies that test samples or ... These assays suffer from a number of limitations: , ... not as commonly available for novel sample matrices such as saliva as they are for ... be relatively costly due to the high volume of reagents used. , ...
Cached Biology Technology:A simple and rapid LC-MS/MS method for the simultaneous determination of nine antiretroviral drugs commonly used in Europe (protease Inhibitors and non-nucleoside reverse transcriptase inhibitors) 2A simple and rapid LC-MS/MS method for the simultaneous determination of nine antiretroviral drugs commonly used in Europe (protease Inhibitors and non-nucleoside reverse transcriptase inhibitors) 3A simple and rapid LC-MS/MS method for the simultaneous determination of nine antiretroviral drugs commonly used in Europe (protease Inhibitors and non-nucleoside reverse transcriptase inhibitors) 4A simple method to sequence from bacterial colonies using [a-33P] radiolabeled ddNTPs and Thermo Sequenase 2A simple method to sequence from bacterial colonies using [a-33P] radiolabeled ddNTPs and Thermo Sequenase 3Simultaneous Screening of 23 Drugs of Abuse in Oral Fluid Using an LC/MS/MS Method 2Simultaneous Screening of 23 Drugs of Abuse in Oral Fluid Using an LC/MS/MS Method 3Simultaneous Screening of 23 Drugs of Abuse in Oral Fluid Using an LC/MS/MS Method 4
HyPro 20 system for slide hybridization. 20 slide capacity. Active vibration system, slide rack and humidity chamber. Ideal for microarray and in situ hybridization....
... PBL's bioassays for interferons are cytopathic effect inhibition ... Sample types include; tissue culture supernatents; serum ... these assays, one unit is defined as the ... the cytopathic effect of viral infection by 50%. ...
Request Info...
Request Info...
Biology Products: