Navigation Links
Reversing ecology reveals ancient environments
Date:2/25/2009

From hair color to the ancestral line of parasitic bacteria, scientists can glean a lot from genes. But imagine if genes also revealed where you lived or who you spent time with. It turns out they do, if you know where and how to look.

Stanford researchers with collaborators at Tel-Aviv University have now laid the foundation for opening such a window to the past using a technique called "reverse ecology." The technique uses genomic data to examine metabolic networks and pulls out proxies for reconstructing bacterial environments millions of years in the past. The work, published in the February issue of the Journal of Computational Biology, offers clues to the complex evolutionary interplay between organisms such as parasites and hosts.

"Based on reverse ecology, you can start with an organism-say, a certain bacterial species that you know nothing about ecologically. But by looking at its genome and metabolic network, you can recreate that past environment the organism lived in," said Elhanan Borenstein, lead author of the paper and a postdoctoral researcher in the Biology Department at Stanford. "And we've done this with hundreds of different species."

Researchers have used genomic data to study metabolic networks-the chemical reactions in metabolism that determine the physiological and biochemical properties of cells-in great detail. But Borenstein, with co-author Marcus Feldman, a professor of biology at Stanford, took this understanding a step further.

Through the metabolic network, organisms accumulate biochemical compounds from their interactions with the surrounding environment (e.g., oxygen, glutamine or sulfate). These molecules also correlate with other environmental properties like temperature and salinity. "This gives us a way to predict the biochemical environment of organisms and learn ecology from the genomic data on a large scale," Borenstein said.

The researchers collected clues about not onl
'/>"/>

Contact: Louis Bergeron
louisb3@stanford.edu
650-725-1944
Stanford University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Hypertension treatment effective in reversing vascular damage
2. Reversing cognitive deficits: Injectable antibody may attack source of problem
3. Rise or fall of reef fish driven by both economy and ecology
4. Federal scientists recognized for contributions to knowledge of bird ecology and habitat
5. Smithsonian scientists receive coveted BBVA Ecology and Conservation Award
6. Lovejoy and Laurance, BBVA Foundation award in ecology
7. Mysterious microbe plays important role in ocean ecology
8. Mysterious microbe may play important role in ocean ecology
9. Minnesota ecology professor wins international award for biodiversity and biofuels research
10. NSF, NIH award Ecology of Infectious Disease grants
11. Tiny invasive snail impacts Great Lakes, alters ecology
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/25/2014)... is a complex congenital central nervous system disease ... the neural tubes during the embryonic phase. Many ... fecal incontinence and neurocognitive retardation. Such problems decrease ... life. Researchers at Ankara Physical Medicine and Rehabilitation ... performance in children with SB, using the Pediatric ...
(Date:7/25/2014)... girls reach puberty is influenced by ,imprinted genes,a subset of ... gene. This is the first evidence that imprinted genes ... of this study were published today in the journal ... menarche, is a marker for the timing of puberty in ... varies between girls, is an inherited trait, and is linked ...
(Date:7/25/2014)... a molecular testing panel developed at UPMC greatly ... surgery for patients with thyroid nodules and cancer, ... Institute (UPCI), partner with UPMC CancerCenter., The test, ... other diagnostic testing agencies, improved the chances of ... percent, according to the study published this month ...
Breaking Biology News(10 mins):Could age of first period influence development of diseases in older women? 2Test increases odds of correct surgery for thyroid cancer patients 2Test increases odds of correct surgery for thyroid cancer patients 3
... European College of Neuropsychopharmacology (ECNP) is pleased to ... 2009 ECNP Neuropsychopharmacology Award in Basic Science Research ... into the neurochemical basis of substance addiction. ... in the field of neuropsychopharmacology and its closely ...
... Researchers have made significant advances in the treatment of metastatic ... treat successfully once it has started to spread according ... congress, ECCO 15 ESMO 34 [1], in Berlin on ... seen rapid and dramatic shrinking of metastatic tumours in patients ...
... research team at the National Institute of Standards and ... possible cancer therapy has uncovered a delicate balancing act ... says they should be. Just like individuals in a ... because they get close together, but not too close. ...
Cached Biology News:Trial of new treatment for advanced melanoma shows rapid shrinking of tumors 2Trial of new treatment for advanced melanoma shows rapid shrinking of tumors 3Therapeutic nanoparticles give new meaning to sugar-coating medicine 2
(Date:7/25/2014)... Sinovac Biotech Ltd. (Nasdaq: SVA ), a leading ... today announced that it will release its unaudited financial results ... close on Thursday, August 14, 2014 EDT. The Company will ... Friday, August 15, 2014, at 8:00 a.m. EDT (Friday, August ... the Company,s financial results and provide an update on recent ...
(Date:7/24/2014)... July 24, 2014 -- A novel combination of microscopy ... of Energy,s Oak Ridge National Laboratory an unprecedented look ... unusual physical and electrochemical properties. , The research ... affects the surface of a perovskite manganite, a complex ... new avenue to understand surface behavior could benefit researchers ...
(Date:7/24/2014)... , July 24, 2014  Now available is a ... Rehealth Regenerative Therapies , located in ... physically active people a new health option: stem ... of age, countless patients suffer from joint and muscle ... as muscle tears, torn rotator cuff, tennis elbow, and ...
(Date:7/24/2014)... -- ECC West Africa, LLC (ECC) signed a contract in ... Hospital (UCH) Ibadan Board of Management for the first ... and operate and maintain a new, state-of-the-art Cancer Institute ... first of the 4-phase project, ECC will conduct feasibility ... Ibadan intends to finance and develop the Cancer Institute ...
Breaking Biology Technology:Sinovac to Host Conference Call to Report Second Quarter 2014 Unaudited Financial Results 2ORNL study reveals new characteristics of complex oxide surfaces 2Stem Cells In Sports Injuries, Joints And Muscular Pain 2Stem Cells In Sports Injuries, Joints And Muscular Pain 3ECC Signs a Contract for the Finance, Design, and Construction of a Premier Cancer Institute in Ibadan, Nigeria 2
... Researcher Appreciation Event ... ... PHOENIX, Oct. 3 ThirdBiotech Inc., http://www.thirdbiotech.com, a biotechnology incubator ... Appreciation Event to be held on Thursday, October 23rd, 2008,between noon and ...
... http://www.amdl.com ),AMDL, Inc. (Amex: ADL ), a leading ... the US, today announced that the,Company will present at ... on Tuesday, October 7, 2008 at 10:30 a.m. ET. ... York Hotel in the Morosco Room., The Maxim ...
... Support R&D Efforts and Clinical Trials Advancing,the ... Oct. 3 Micromet, Inc. (Nasdaq:,MITI) ("Micromet" ... proprietary antibodies for the treatment of cancer, ... has closed its previously,announced $40 million private ...
Cached Biology Technology:First Annual Arizona Biotech Day Announced for October 23rd 2008 2First Annual Arizona Biotech Day Announced for October 23rd 2008 3AMDL, Inc. to Present at Maxim Group Growth Conference October 7, 2008 2AMDL, Inc. to Present at Maxim Group Growth Conference October 7, 2008 3Micromet Closes $40 Million Private Equity Placement 2Micromet Closes $40 Million Private Equity Placement 3Micromet Closes $40 Million Private Equity Placement 4
... It has been demonstrated that oxidative stress ... and cancer. Oxidative stress is the condition ... and physiological antioxidants exist leading to the ... response to oxidative stress is through several ...
... Human Serum-Single Donor • Human serum is ... found to be negative by a test ... Antibodies to Human Immunodeficiency Virus (Anti-HIV 1/2), ... Hepatitis B Surface Antigen (HbsAg) and Non-reactive ...
... Clean-up Micro Kit provides a fast and simple ... X-100 and other detergents from small samples of ... patented protein resin as an ion exchanger. Each ... of either acidic or basic protein.A complete kit ...
Compound(s) screened through any number of client selected assays. Client also selects number of concentrations and replicates....
Biology Products: