Navigation Links
Reversing aging
Date:10/17/2011

neurons compared to the billions of neurons in the human brain, the worms have a genetic makeup similar to humans making them prime for testing drugs.

Researchers in Pierce-Shimomura's lab engineered a new strain of worm that develops Alzheimer's disease. Just as in humans, a subset of the worm's brain degenerates in "middle age" which conveniently is only 5-days-old in the tiny worms. The dying neurons can be visualized easily through the transparent body. The researchers have recently discovered that candidate drugs for treating human Alzheimer's disease also prevent the death of neurons in their worm model. This result provides the basis to use their worm model to search for new drugs that may delay or prevent neurodegeneration in humans.

It will be up to Ben-Yakar to develop the novel optical techniques and microfluidic devices capable of determining within a matter of seconds which drugs are effective at repairing or regenerating neurons within the worms.

Ben-Yakar, whose engineering feats already include developing a precise laser nanosurgery for nerve regeneration studies in C. elegans and the first laser microscalpels capable of removing cancerous cells without damaging neighboring cells, said the worms will be genetically engineered to have color-coded neurons with florescent probes. Neurons in the worm that emit a strong florescent signal will indicate that the specific neurons in the worm are healthy and that the drug being tested is working.

"Using Adela's microfluidic system, we will automate the monitoring of the nervous system, enabling us to test how millions of candidate medicines might prevent or delay neurodegeneration," said Pierce-Shimomura, an assistant professor in the Section of Neurobiology. "A drug screen of this size has never been attempted."

Research is personal

For Ben-Yakar and Pierce-Shimomura, the research is as much about scientific discovery as it is a personal cause
'/>"/>

Contact: Melissa Mixon
melissa.mixon@austin.utexas.edu
512-471-2129
University of Texas at Austin
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. New breathing therapy reduces panic and anxiety by reversing hyperventilation
2. Study reveals new possibility of reversing damage caused by MS
3. Preventing or reversing inflammation after heart attack, stroke may require 2-pronged approach
4. Reversing ecology reveals ancient environments
5. Open-access publication in JoVE receives sponsorship from Carl Zeiss MicroImaging
6. Researchers study agings effect on the brain
7. Organic medical imaging system to detect disease and track medication
8. Scripps and Complete Genomics to collaborate on genetic research study on healthy aging
9. Managing future forests for water
10. UCLA researchers develop system that finds prostate cancer spread earlier than conventional imaging
11. Scientists turn back the clock on adult stem cells aging
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/13/2015)... 13, 2015  higi, a leading cloud-based consumer engagement ... fully engage with their communities around health and wellness, ... and secure API.  ... accessible, affordable, and convenient vehicle to receive validated health ... The API will allow higi,s trusted partners, ...
(Date:4/9/2015)... Calif. , April 9, 2015 Synaptics ... interface solutions, announced today that it will report financial ... Thursday, April 23, 2015, after the close of market. ... analysts and investors at 2:00 p.m. PT (5:00 p.m. ... To participate on the live call, analysts ...
(Date:4/6/2015)... Conn. , Apr. 6, 2015 NXT-ID, ... "Company"), a biometric authentication company focused on the ... has filed provisional patent 62/143028 for ... COMMUNICATIONS AND ENERGY TRANSFER  NXT-ID introduces a ... payments. This patent surrounds the use of miniature ...
Breaking Biology News(10 mins):higi Launches Seamless Access to HIPAA-Compliant Health Outcomes and Activity Data 2higi Launches Seamless Access to HIPAA-Compliant Health Outcomes and Activity Data 3Synaptics to Report Third Quarter Results on April 23 2NXT-ID Patents Miniature, Low Power Wireless Magnetic Stripe 2NXT-ID Patents Miniature, Low Power Wireless Magnetic Stripe 3NXT-ID Patents Miniature, Low Power Wireless Magnetic Stripe 4
... Ky. -- A new study co-authored by the University ... progesterone to women who are at a high risk ... premature delivery. The new study, published in the ... a two-prong strategy used by doctors: participating pregnant women ...
... release is available in German . ... Europe will participate. Research under BioBoost will complement the bioliq ... designer fuels for diesel and Otto engines from biogenous residues, ... resources based on residual biomass. BioBoost is one of only ...
... researchers at the California Academy of Sciences added 140 new relatives ... 31 sea slugs, 13 fishes, 11 plants, nine sponges, three corals, ... dozen Academy scientists along with several dozen international collaborators. ... things to discover on Earth, the scientists made their finds over ...
Cached Biology News:New study shows promise for preventing preterm births 2KIT: BioBoost - Boost of biomass-based energy 2140 new species described by California Academy of Sciences in 2011 2140 new species described by California Academy of Sciences in 2011 3140 new species described by California Academy of Sciences in 2011 4
(Date:5/20/2015)... Park, CA, Mulhouse, France, Cambridge, MA (PRWEB) May ... leading provider of high quality transporter assay services ... Safety and Pharmacology, and Rhenovia Pharma, a world ... on neurotransmission using Translational Quantitative Systems Pharmacology supported ... a partnership agreement. , The agreement allows both ...
(Date:5/20/2015)... May 20, 2015  HOSTING, the leading provider ... it is an official partner of the ... Cooperative Members Services Program. This unique collaboration ... cloud services and best practices derived from ... and service providers, enabling member healthcare organizations ...
(Date:5/20/2015)... May 20, 2015 (PRWEB) May 20, 2015 ... Computer Aided Engineering software, today announced the release of ... the 0D and 1D management and analyses of chemical ... Steve Portal, now features a library generation functionality ... new fuel blends and operating conditions for simulations with ...
(Date:5/20/2015)... The Honey Bee Health Coalition applauded ... Health of Honey Bees and other Pollinators and the ... Barack Obama’s Pollinator Health Task Force. The Strategy ... honey bees and other pollinators that support billions of ... sets clear goals for pollinator health that underscore the ...
Breaking Biology Technology:Optivia Biotechnology Inc. and Rhenovia Pharma Sign Partnership Agreement 2Optivia Biotechnology Inc. and Rhenovia Pharma Sign Partnership Agreement 3HOSTING Named Partner of the CHIME Cooperative Member Services Program 2HOSTING Named Partner of the CHIME Cooperative Member Services Program 3CD-adapco’s New DARS v2.10 Release Enhances User Capabilities 2CD-adapco’s New DARS v2.10 Release Enhances User Capabilities 3Honey Bee Health Coalition Ready to Provide Leadership in Implementing National Pollinator Health Strategy 2Honey Bee Health Coalition Ready to Provide Leadership in Implementing National Pollinator Health Strategy 3Honey Bee Health Coalition Ready to Provide Leadership in Implementing National Pollinator Health Strategy 4Honey Bee Health Coalition Ready to Provide Leadership in Implementing National Pollinator Health Strategy 5Honey Bee Health Coalition Ready to Provide Leadership in Implementing National Pollinator Health Strategy 6Honey Bee Health Coalition Ready to Provide Leadership in Implementing National Pollinator Health Strategy 7
... T. Bakalinsky Department of Food Science and Technology, , ... Abstract , ... compared to those of a standard laboratory karyotype. Qualitative analysis ... of the wine strains are aneuploid , ...
... , Introduction , ... stain useful , in polyacrylamide gel analysis in 1979 ... PAGE silver stain was of the silver diammine type adapted from early histological , ... a faster, more reliable, , and very sensitive silver ...
... Eric Larson, Bio-Rad Laboratories, 2000 Alfred Nobel Drive, Hercules, , ... Introduction , ... medium for the harsh chemical environment of N-terminal, or Edman degradation, , ... step in alcohol, its high protein binding capacity, target retention, ...
Cached Biology Technology:Electrophoretic Karyotypes of Wine Strains of Saccharomyces cerevisiae 2Electrophoretic Karyotypes of Wine Strains of Saccharomyces cerevisiae 3Electrophoretic Karyotypes of Wine Strains of Saccharomyces cerevisiae 4Electrophoretic Karyotypes of Wine Strains of Saccharomyces cerevisiae 5Electrophoretic Karyotypes of Wine Strains of Saccharomyces cerevisiae 6The Bio-Rad Silver Stain, Rev E 2The Bio-Rad Silver Stain, Rev E 3The Bio-Rad Silver Stain, Rev E 4The Bio-Rad Silver Stain, Rev E 5The Bio-Rad Silver Stain, Rev E 6The Bio-Rad Silver Stain, Rev E 7The Bio-Rad Silver Stain, Rev E 8The Bio-Rad Silver Stain, Rev E 9The Bio-Rad Silver Stain, Rev E 10The Bio-Rad Silver Stain, Rev E 11The Bio-Rad Silver Stain, Rev E 12The Bio-Rad Silver Stain, Rev E 13The Bio-Rad Silver Stain, Rev E 14The Bio-Rad Silver Stain, Rev E 15The Bio-Rad Silver Stain, Rev E 16Application-Specific PVDF Membranes: Immun-Blot PVDF Membrane for Western Blotting and Sequi-Blot PVDF Membrane for Protein Sequencing, Rev C 2Application-Specific PVDF Membranes: Immun-Blot PVDF Membrane for Western Blotting and Sequi-Blot PVDF Membrane for Protein Sequencing, Rev C 3
Rabbit polyclonal to LCAT ( Abpromise for all tested applications). entrezGeneID: 3931 SwissProtID: P04180...
HAMP Immunogen: HAMP (AAH20612, 25 a.a. ~ 85 a.a) full length recombinant protein with GST tag. Storage: -20 C, Avoid Freeze/Thaw Cycles *Available for distribution in the US only...
... Recognizes Nabeta2. The epitope specific ... in any other known proteins.,SPECIES ... to work on human because ... conserved (17/19 residues). Reactivity with ...
Chicken polyclonal to DCTD ( Abpromise for all tested applications). Antigen: Full length protein (Human) Entrez GeneID: 1635 Swiss Protein ID: P32321...
Biology Products: