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Revealing the secrets of motility in archaea
Date:2/14/2013

p>"A mechanistic understanding of microbial movements is critical to assessing their impacts on planet-scale recycling of elements, climate change, and medicine," Tainer says. "We have studied Type IV pili systems for over a decade, including the ATPases needed for pathogen movement. Now this novel archaellum system allowed us to capture and genetically test a phosphate-release intermediate and other conformations that change our understanding of how the motors for all these broadly related microbial systems of movement and secretion work."

While many questions remain, the MPI-Berkeley Lab collaboration has already produced the first and only in-depth structural study on an archaellum protein, another step toward solving the mysteries of Archaea, the third domain, besides Bacteria and Eukarya, of the Tree of Life.


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Contact: Paul Preuss
paul_preuss@lbl.gov
510-486-6249
DOE/Lawrence Berkeley National Laboratory
Source:Eurekalert  

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