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Retrovirus replication process different than thought
Date:7/15/2010

tand the smallest building blocks of the virus particle," Parent said. "If we interfere with the first step, the virus will never be released from the cell. Cells are complex, so we use the key elements in a test tube to figure out how Gag and the RNA interact."

This study built on a 2002 paper, which proposed a model for the Gag protein's entry into the nucleus. The researchers reported in the Proceedings of the National Academy of Sciences that Gag does travel in the nucleus. Further study will examine how the Gag complex travels from the nucleus to the plasma membrane.


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Contact: Matt Solovey
msolovey@hmc.psu.edu
717-531-8606
Penn State
Source:Eurekalert

Page: 1 2

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