Navigation Links
Results from trials of DHA in Alzheimer's disease and age-related cognitive decline
Date:7/11/2009

oil is abundant in some marine microalgae, which provide the DHA that makes fatty fish a good source of DHA. Dietary DHA is also available in foods enriched with algal DHA or fish oils, and dietary supplements. Previous animal studies and epidemiology in humans suggested that DHA may be beneficial in people with Alzheimer's.

Alzheimer's Disease Cooperative Study 18-Month DHA Trial in Alzheimer's Disease

Researchers from the National Institute on Aging (NIA)-supported Alzheimer's Disease Cooperative Study (ADCS), led by Joseph Quinn, MD, Associate Professor of Neurology at Oregon Health and Sciences University, conducted a double blind, randomized, placebo-controlled clinical trial comparing DHA and placebo in 402 people (average age=76) diagnosed with mild to moderate Alzheimer's at 51 sites in the U.S.

At the beginning of the trial, all participants had a dietary DHA intake of less than 200 mg per day. Subjects were treated with DHA or placebo at a dose of two grams per day for 18 months. Those participants already taking approved Alzheimer's drugs could continue taking them during the trial. Co-primary outcomes were rate of change on the Alzheimer's disease assessment scale-cognitive (ADAS-cog) and rate of change on Clinical Dementia Scale-sum of the boxes (CDR-SOB). These two measures are the current standard tests used by FDA when assessing new Alzheimer's drugs.

According to the researchers, treatment with DHA clearly increased blood levels of DHA, and also appeared to increase brain DHA levels, based on a measured increase of DHA in study participants' cerebrospinal fluid (CSF). However, DHA treatment did not slow the rate of change on tests of mental function (ADAS-cog), global dementia severity status (CDR-SOB), activities of daily living (ADL), or behavioral symptoms (NPI) in the study population as a whole. There was no different treatment effect between the mild and moderate Alzheimer's patients.

"These tri
'/>"/>

Contact: Niles Frantz
niles.frantz@alz.org
312-363-8782
Alzheimer's Association
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Many parents at-risk for cancer disclose genetic test results to children
2. BIO-key Reports Second Quarter 2007 Results
3. Communication Intelligence Corporation Reports Second Quarter 2007 Financial Results
4. New CPR promises better results by compressing abdomen, not Chest
5. Positive results for airway bypass
6. 2 carotid artery stenting studies show results comparable to AHA guidelines
7. Measurement Specialties, Inc. Announces Impact of German Business Tax Reform 2008 Resulting in Lower Combined German Tax Rate - Impacts 2Q08 Reported Financial Results
8. BIO-key Reports Third Quarter 2007 Results
9. New clinical trial results show how personalized medicine will alter treatment of genetic disorders
10. Electrospray droplet research yields surprising, practical results
11. Aware, Inc. Reports Fourth Quarter and 2007 Financial Results
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... they are the ultimate source of all organic matter ... on algae, too, to suck up climate-warming carbon dioxide ... of the ocean. Now, by using a combination of ... that viruses infecting those algae are driving the life-and-death ... stays essentially the same, and this has important implications ...
(Date:8/21/2014)... researchers from Beth Israel Deaconess Medical Center (BIDMC ) ... Most Influential Scientific Minds 2014," a comprehensive list ... web resource for science metrics and research performance analysis. ... most influential "are performing and publishing work that their ... science," according to a Thomson Reuters statement. Researchers were ...
(Date:8/21/2014)... 18-22, 2014 , WHERE: , San Diego ... CA 92101 , WHAT: , Invited and ... latest research in human genetics. Examples of sessions ... on rare genetic variants in health and disease, ... sun sensitivity (Saturday, Oct. 18, 5:30-7:30 pm) , ...
Breaking Biology News(10 mins):Viruses take down massive algal blooms, with big implications for climate 2BIDMC researchers named among 'the most influential scientific minds' 2BIDMC researchers named among 'the most influential scientific minds' 3American Society of Human Genetics 2014 Annual Meeting 2
... mothers are at risk for iron deficiency, which could ... be presented Saturday, April 30, at the Pediatric Academic ... adults, obesity-related inflammation hinders the transport of iron through ... When a woman is pregnant, iron is transferred through ...
... Federal Court of Appeals has overturned an August 2010 ban ... way for broader exploration of how stem cells function and ... of currently incurable diseases. The ruling has been welcomed ... in 2009, and by the nation,s top researchers in the ...
... New Rochelle, NY, April 29, 2011Videoscopy, a ... monthly publication, Journal of Laparoendoscopic & ... by Mary Ann Liebert, Inc., publishers ( ... fully peer-reviewed surgical and microinvasive demonstrations of ...
Cached Biology News:US Appeals Court opens federal funding for stem cell research 2Groundbreaking minimally invasive surgical videojournal launched by Mary Ann Liebert Inc. 2
(Date:8/21/2014)... , Aug. 21, 2014 OTC ... Pharmaceuticals Inc., a biotechnology company, on its approval ... previously traded on OTCQX®, the best marketplace for ... Markets Group. Logo - http://photos.prnewswire.com/prnh/20110118/MM31963LOGO ... the successful execution of its growth strategy and ...
(Date:8/21/2014)... 2014 Pursuit Solutions ( http://www.pursuit-solutions.com ... and services for Life Sciences sales and marketing ... of New Commercial Sales Models” by Peter Robinson, ... The article examines some innovative models used to ... tested in the pharmaceutical market. Robinson grades the ...
(Date:8/21/2014)... Boston, MA (PRWEB) August 21, 2014 ... collaboration company, has been recognized as one of ... 500 | 5000 magazine for the 2nd consecutive ... on its 33rd annual Inc. 500|5000, an exclusive ... list represents the most comprehensive look at the ...
(Date:8/20/2014)... patented university inventions licensed to biotechnology firms has ... To open these roadblocks, the researchers suggest that ... discovery stage could lead to faster commercialization down ... from discoveries made in university laboratories and licensed ... clinical trials, which have a high failure rate. ...
Breaking Biology Technology:OTC Markets Group Congratulates Immune Pharmaceuticals on NASDAQ Listing 2Pursuit's Peter Robinson Publishes "Grading Pharma's Use of New Commercial Sales Models" 2SoundConnect Returns on Inc. 5000 List of Fastest Growing Companies 2SoundConnect Returns on Inc. 5000 List of Fastest Growing Companies 3Early bottlenecks in developing biopharmaceutical products delay commercialization 2Early bottlenecks in developing biopharmaceutical products delay commercialization 3
... Event to focus on nanomedical applications in diagnostics, imaging, and ... ... The Nano-Network, Cleveland Clinic,Lerner Research Institute, and Case Western Reserve ... to,explore the use of nanoparticles for diagnostics, imaging and therapeutics,to improve ...
... Calif., July 8 Arete Therapeutics Inc., a,privately-held ... today announced the appointment of,James Sabry, M.D., Ph.D., ... been a strategic advisor and member of the ... Dinesh Patel in the position of,president and chief ...
... ANN ARBOR, Mich., July 8 NanoBio(R) Corp., ... to prevent and treat infectious diseases, today announced ... board of directors., Dr. Dubin currently serves ... a leading healthcare and biotechnology investment banking firm., ...
Cached Biology Technology:NanoMedicine Summit Returns to Cleveland, September 25-26 2NanoMedicine Summit Returns to Cleveland, September 25-26 3NanoMedicine Summit Returns to Cleveland, September 25-26 4Arete Therapeutics Names James Sabry, M.D., Ph.D., President and Chief Executive Officer 2Daniel B. Dubin, M.D., Joins NanoBio Corp.'s Board of Directors 2
Ready-to-use solution....
Applications: ISH...
TRIzol Reagents are ready-to-use monophasic solutions of phenol and guanidine isothiocyanate suitable for isolating total RNA DNA and proteins (16)....
Anti-ZFP-38/RU49 Family: Zinc Finger Peptide Sequence: SVKVEDKDFPSTCSKK...
Biology Products: