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Researchers use nanoscale 'patches' to sensitize targeted cell receptors
Date:11/25/2013

controlling which peptides are on the patch, we can influence the cell's activity. And by manipulating the placement of the patch, we can control where that activity takes place."

The patch itself is made of DNA that researchers have programmed to self-assemble into flexible, two-dimensional sheets. The sheets themselves incorporate molecules called biotin and streptavidin which serve to hold and organize the peptides that are used to sensitize cell receptors.

"These peptides can bind with cell receptors and sensitize them, without blocking the interaction between the receptors and their target ligands," Pedersen says. "That's what makes this approach work."


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Contact: Matt Shipman
matt_shipman@ncsu.edu
919-515-6386
North Carolina State University
Source:Eurekalert

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