Navigation Links
Researchers uncover why the body can't defend against tuberculosis
Date:11/14/2011

ecome engulfed by macrophages, they secrete a protein named PtpA that disables the two separate mechanisms required for making the acidic environment that normally targets them. The end result is that Mtb lives comfortably in the immune cells, like a Trojan horse, hidden from the rest of the immune system. The bacteria then multiply inside the macrophage, and when released, they attack the body.

"We have been engaged in studying the interaction between the TB bacterium and the human macrophage over the past decade," says Dr. Av-Gay. "We are delighted with this discovery. Through learning about the tricks it uses, we now have new targets, so that we can develop better drugs against this devastating disease."

TB is the leading cause of death among infectious diseases in the world today and is responsible for one in four adult preventable deaths, according to the World Health Organization (WHO). Every 20 seconds TB kills someone, with approximately 4400 people dying every day. The WHO estimates that one-third of the world's population is infected.


'/>"/>

Contact: Lisa Carver
lisa.carver@vch.ca
604-875-4111 x61777
University of British Columbia
Source:Eurekalert

Page: 1 2

Related biology news :

1. NC State researchers get to root of parasite genome
2. Researchers find animal with ability to survive climate change
3. Researchers find an essential gene for forming ears of corn
4. Researchers note differences between people and animals on calorie restriction
5. Researchers study acoustic communication in deep-sea fish
6. Researchers discover that growing up too fast may mean dying young in honey bees
7. Researchers study how pistachios may improve heart health
8. UI researchers find potentially toxic substance present in Chicago air
9. Researchers develop new self-training gene prediction program for fungi
10. Case Western Reserve University researchers track Chernobyl fallout
11. Childrens National researchers develop novel anti-tumor vaccine
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2014)... Lewis Carroll,s Through the Looking Glass, collaborators from ... Singapore improved a 35-year-old ecology model to better ... of years. , The new model, called a ... Queen Effect," an evolutionary hypothesis introduced by Lee ... organisms must constantly increase their fitness (or ability ...
(Date:7/30/2014)... the Entomological Society of America (ESA) has elected ten ... as a Fellow acknowledges outstanding contributions to entomology in ... or administration. The following Fellows will be recognized during ... will be held November 16-19, 2014 in Portland, Oregon. ... professor with the Department of Plant, Soil and Entomological ...
(Date:7/30/2014)... pledge of $1 million from the Cornelia Cogswell Rossi ... Biometry Center. , The newly established Connie ... to develop a greater breadth and depth of knowledge ... the pace of research to improve human health. , ... for the Laboratory and its external partners, supporting research ...
Breaking Biology News(10 mins):Classic Lewis Carroll character inspires new ecological model 2Classic Lewis Carroll character inspires new ecological model 3Entomological Society of America recognizes 2014 fellows 2Entomological Society of America recognizes 2014 fellows 3Entomological Society of America recognizes 2014 fellows 4Entomological Society of America recognizes 2014 fellows 5Entomological Society of America recognizes 2014 fellows 6Entomological Society of America recognizes 2014 fellows 7Entomological Society of America recognizes 2014 fellows 8Entomological Society of America recognizes 2014 fellows 9Entomological Society of America recognizes 2014 fellows 10Entomological Society of America recognizes 2014 fellows 11Entomological Society of America recognizes 2014 fellows 12Entomological Society of America recognizes 2014 fellows 13Entomological Society of America recognizes 2014 fellows 14Entomological Society of America recognizes 2014 fellows 15Entomological Society of America recognizes 2014 fellows 16Entomological Society of America recognizes 2014 fellows 17Rossi Foundation pledges $1M for JAX neurobehavioral research center 2
... is available in German . Much ... Research Foundation (DFG) has approved funding for a long-term research ... from Bielefeld University and Dr. Frank Spinath from Saarland University. ... the example of 4,000 pairs of twins living in Germany. ...
... and produce offspring of mixed ancestry? Recent genetic ... modern humans tens of thousands of years ago in ... pool. But the findings are not universally accepted, and ... role of interbreeding, which is also known as hybridization. ...
... living organisms on the planet, the big, old trees that ... A report by three of the world,s leading ecologists ... of an alarming increase in deathrates among trees 100-300 years ... areas and even in cities. "It,s a worldwide problem ...
Cached Biology News:German Research Foundation to fund globally unique twin study on social inequality 2Monkey business: What howler monkeys can tell us about the role of interbreeding in human evolution 2Monkey business: What howler monkeys can tell us about the role of interbreeding in human evolution 3The world's big trees are dying 2The world's big trees are dying 3
(Date:7/30/2014)... A study presented at the 2014 ... of CSL Behring,s C1 Inhibitor (C1-INH) concentrate in ... sensitized patients. C1-INH is a human protein and ... The study shows that post-transplant treatment with ... of complement components 3 and 4, suggesting that ...
(Date:7/30/2014)... 2014 Sales Horizons, a leader in ... sales training programs for companies engaged in complex B2B ... by thousands of salespeople over 25 years in market-leading ... can be customized to address the unique sales challenges ... sales training program consists of two parts: Mastering ...
(Date:7/30/2014)... July 30, 2014 Vycom announces the ... products, designed to meet Factory Mutual (FM) 4910 fire ... such as wet benches, process tools, fume hoods, furniture ... and damage to semiconductor wafers used in electronic chip ... flame-retardant PVC solution with excellent workability and superior aesthetics. ...
(Date:7/30/2014)...   Epic Sciences, Inc. ("Epic"), a private ... personalize and advance the treatment and management of cancer, ... as chairman of Epic,s board of directors. Mr. ... (formerly Invitrogen). Mr. Lucier joins Epic,s board of directors ... cell analysis platform with special focus on the development ...
Breaking Biology Technology:Study Suggests C1-INH May Aid in Prevention of Antibody-Mediated Rejection Following Kidney Transplant 2Study Suggests C1-INH May Aid in Prevention of Antibody-Mediated Rejection Following Kidney Transplant 3Sales Horizons Launches New Blended Sales Training Programs to Companies Engaged in Complex B2B Sales 2Sales Horizons Launches New Blended Sales Training Programs to Companies Engaged in Complex B2B Sales 3Vycom Announces Flametec® Thermax PVC (FM4910 Listed) For a Variety of Clean Room Applications with Excellent Workability and Aesthetics 2Epic Sciences Appoints Greg Lucier as Chairman of the Board of Directors 2Epic Sciences Appoints Greg Lucier as Chairman of the Board of Directors 3
... Courtesy of Optima Batteries. Milwaukee ... Johnson Controls , has announced the latest addition to ... the dual-purpose Group 75/25 and 35 models. Both models ... by a growth of in-car electronics. , ,YellowTop batteries ...
... site connecting companies with potential members of their boards of ... Candela Solutions, LLC , and Michael Best and Friedrich, ... signing up companies and people and will add free search ... the curve on this," said Ronald Kral, a founding partner ...
... off its strategy of digital convergence on Thursday at the ... new home entertainment service. , ,Designed as part of ... together satellite TV, digital video recording and Internet service in ... dish and DSL connection. , ,In his keynote address, SBC ...
Cached Biology Technology:SBC blends TV, video, music and the Internet in a new media box 2
Rat monoclonal [20d5] to NKG2A + C+ E ( Abpromise for all tested applications). Antigen: Tissue / cell preparation (Mouse): CHO transfected cells expressing the B6 allele of NKG2A. Entrez Gen...
... has recently launched a custom synthesis ... (siRNA). Thermos siRNA molecules are: ... 2 DNA bases overhang at the ... Delivered fully deprotected and ready-to-use. ...
Rabbit polyclonal to STUB1 ( Abpromise for all tested applications). entrezGeneID: 10273 SwissProtID: Q9UNE7...
... orbital shaker stands both present ... ergonomic height, and help protect ... welded tubular steel, these heavy-duty ... the weight and minimize the ...
Biology Products: