Navigation Links
Researchers uncover secrets of internal cell fine-tuning
Date:7/29/2014

New research from scientists at the University of Kent has shown for the first time how the structures inside cells are regulated a breakthrough that could have a major impact on cancer therapy development.

A team from Kent's School of Biosciences uncovered the mechanism whereby the physical properties of the internal structures within cells known as actin filaments are 'fine-tuned' to undertake different functions.

While some of these actin filaments appear to completely stable, providing a framework for the cell, others are more dynamic, allowing the cell to respond rapidly to changes in its environment.

The researchers - PhD students Matthew Johnson and Daniel East, who were led by Dr Daniel Mulvihill - used yeast cells to mimic those in humans. They utilised a novel biology 'trick' to switch the location of molecules which bind to, and stabilise, the actin polymer and modulate the movement of molecular motors.

In this way, they uncovered the mechanism which determines the functional characteristics of actin filaments in all cells and orchestrates cellular activity. It is expected the breakthrough could have a major impact on the development of therapies for a variety of diseases, including cancer.


'/>"/>

Contact: Martin Herrema
M.J.Herrema@kent.ac.uk
01-227-823-581
University of Kent
Source:Eurekalert

Page: 1

Related biology news :

1. Whitehead Institute researchers create naïve pluripotent human embryonic stem cells
2. UNC researchers find unsuspected characteristics of new CF drugs, offering potential paths to more effective therapies
3. York University researchers use bird backpacks to put wood thrushes migration on the map
4. Intestinal parasites are old friends, researchers argue
5. UNH NHAES researchers work to save endangered New England cottontail
6. Researchers create vaccine for dust-mite allergies
7. Cleveland Clinic researchers discover neuroprotective role of immune cell
8. Researchers provide guide to household water conservation
9. UCI researchers find epigenetic tie to neuropsychiatric disorders
10. Researchers simplify process to purify water using seed extracts
11. BIOTEC researcher is one of the Highly Cited Researchers 2014
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/6/2017)... Jan. 5, 2017  Delta ID Inc., a leader ... technology for automotive at CESĀ® 2017. Delta ID has ... to demonstrate the use of iris scanning as a ... the driver in a car, and as a way ... experience. Delta ID and Gentex will demonstrate ...
(Date:1/3/2017)... Jan. 3, 2017 Onitor, provider of digital ... Onitor Track, an innovative biometric data-driven program designed to ... month at the 2017 Consumer Electronics Show (CES) in ... In the U.S., the World Health Organization (WHO), have ... of adults who are overweight or obese. WHO also ...
(Date:12/20/2016)... -- The rising popularity of mobility services such ... significant interest in keyless access systems. Following the ... (BLE), biometrics and near-field communication (NFC) are poised ... technologies in the automotive industry. This evolution from ... opens the market to specialist companies such as ...
Breaking Biology News(10 mins):
(Date:1/19/2017)... HOUSTON , Jan. 19, 2017 ... formation of its Medical/Clinical Advisory Board.  This new ... who enhance the range and depth of expertise ... its novel prenatal diagnostic tests.  These experts are ... guidance for the company,s product development and commercialization ...
(Date:1/19/2017)... Jan 19, 2017 Research and Markets ... has announced the addition of the ... - Forecast to 2025" report to their offering. ... The report provides a detailed analysis on current and future market ... 2025, using estimated market values as the base numbers ...
(Date:1/19/2017)... ... 2017 , ... November Research Group, LLC, a global leader ... manufacturers and regulators, is proud to announce the worldwide release of PRIMO Mail. ... provide product vigilance departments with the flexibility and ease of use of a ...
(Date:1/19/2017)... CALABASAS, Calif. , Jan. 19, 2017 /PRNewswire/ ... Mathias Schmidt , Ph.D., as chief executive ... board of directors. Dr. Schmidt brings to ArmaGen more ... on the research and development of biotherapeutics and ... biopharmaceutical executive with the diverse experience and skillset ...
Breaking Biology Technology: