Navigation Links
Researchers uncover new piece to the puzzle of human height
Date:1/13/2008

n a quantitative trait such as height, researchers survey each participants complete set of DNA, or genome, looking for strategically selected markers of genetic variation.

If average height differs for individuals with certain genetic variants, this indicates that something in that chromosomal neighborhood likely influences height. In this particular study, researchers initially examined the effects of more than 2 million genetic variants. The variants detected using this approach can accurately point to the region of the genome involved, but may not themselves directly influence the trait. This means researchers often need to take additional steps, such as sequencing the DNA in that particular region of the genome, to identify the exact genetic variant that affects the trait.

The completion of the map of human genetic variation, or HapMap, has fueled a surge in genome-wide association studies, with most of the increase coming in the past 10 months. Researchers around the globe have now associated more than 60 common DNA variants with the risk of more than 20 common diseases or related traits.

Genome-wide association studies often require the skills of researchers from many different institutions and many different disciplines. By working together in a collaborative manner, we can tackle the complexities of common disease and quantitative traits far more efficiently than we could working alone, said Gonalo R. Abecasis, D.Phil., a statistical geneticist of the University of Michigans School of Public Health, Ann Arbor, who co-directed the analyses with Dr. Mohlke.

This latest work was accomplished as a result of innovative international partnerships with scientists and study participants. Researchers began by scanning the genomes of nearly 4,300 people from the Mediterranean island of Sardinia and more than 2,300 people from Finland. The initial findings were then validated by follow-up studies involving more than 24,000 additi
'/>"/>

Contact: Geoff Spencer
spencerg@mail.nih.gov
301-402-0911
NIH/National Human Genome Research Institute
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Researchers identify proteins involved in new neurodegenerative syndrome
2. Texas researchers and educators head for Antarctica
3. MGH researchers describe new way to identify, evolve novel enzymes
4. University of Pennsylvania researchers develop formula to gauge risk of disease clusters
5. U of MN researchers discover noninvasive diagnostic tool for brain diseases
6. U of Minnesota researchers discover noninvasive diagnostic tool for brain diseases
7. Researchers discover new strategies for antibiotic resistance
8. Researchers find new taste in fruit flies: carbonated water
9. Binghamton University researchers investigate evolving malaria resistance
10. UIC researchers find promising new targets for antibiotics
11. Researchers develop simple method to create natural drug products
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/21/2015)... GOTHENBURG, Sweden , July 21, 2015 ... sensor FPC1025. Already received as well as expected revenues in 2015 ... included in FPC,s communicated revenue guidance of approximately 2,200 MSEK for ... is a leading smartphone manufacturer in China ... selected FPC1 02 5 for Axon ...
(Date:7/13/2015)... OXFORD, Conn. , Jul. 13, 2015 /PRNewswire/ ... the "Company"), a biometric authentication company focused on ... it has filed provisional patent 62/188684 for ... NXT-ID achieves another new convenient and secure method ... expands new, innovative payment methods, introduced with its ...
(Date:7/8/2015)... YORK , July 8, 2015 Summary ... globally, and the fourth most fatal, with a mortality ... The poor prognosis of pancreatic cancer patients has highlighted ... treatment, which is not being met by the current ... an array of products with varying molecule types and ...
Breaking Biology News(10 mins):FPC's Touch Fingerprint Sensor FPC1025 in ZTE's Smartphone Axon 2NXT-ID Patents Behavior-Directed Payments 2NXT-ID Patents Behavior-Directed Payments 3NXT-ID Patents Behavior-Directed Payments 4Frontier Pharma: Pancreatic Cancer - Identifying and Commercializing First-in-Class Innovation 2Frontier Pharma: Pancreatic Cancer - Identifying and Commercializing First-in-Class Innovation 3
... team of Montral researchers at the IRCM led by Dr. ... team at Duke University in the United States, discovered that ... by affecting certain types of cognitive performance such as anxiety, ... scientific journals Proceedings of the National Academy of Sciences ...
... simple experiment, a scientist exposes rats to a certain ... symptoms remarkably similar to those seen in Parkinson,s patients. ... disease, which affects 7 million to 10 million people ... Chemical & Engineering News , the weekly newsmagazine of ...
... science team led by researchers at Scripps Institution of Oceanography ... the impact of fishing on a group of fish known ... in the journal Proceedings of the Royal Society B ... conservation targets to protect and preserve fragile coral reefs. ...
Cached Biology News:An important discovery related to anxiety disorders and trauma 2An important discovery related to anxiety disorders and trauma 3Scripps leads first global snapshot of key coral reef fishes 2Scripps leads first global snapshot of key coral reef fishes 3
(Date:7/29/2015)... 2015 Sanofi, a global ... second quarter of 2015. CEO Olivier Brandicourt ... performance in different businesses. Watch video ... Topics covered in the interview ... - Performance drivers - Diabetes ...
(Date:7/29/2015)... /PRNewswire/ - BioAmber Inc. (NYSE: BIOA ) today announced ... Officer has resigned.  The Company has hired Andrew ... in December 2014, as full time interim CFO and ... Andy Ashworth began his employment today, ... transition.  Andy was the Company,s CFO from September 2011 ...
(Date:7/29/2015)... Wis. (PRWEB) , ... July 29, 2015 , ... ... identification solutions, today announced its GHS Label Guide . To align chemical ... System (GHS), this guide includes explanations of label components, an example of an ...
(Date:7/29/2015)... ... 2015 , ... The third Medical Innovation Impact Index (MI3) Alert considers FDA ... combinations. The current system received a score of 0 (range -10 to +10) for ... of Fairleigh Dickinson University’s ( FDU ) Rothman Institute of Innovation and Entrepreneurship. ...
Breaking Biology Technology:BioAmber Announces Change in Chief Financial Officer 2BioAmber Announces Change in Chief Financial Officer 3Brady Announces a New GHS Label Guide 2Third Medical Innovation Impact Index Issued by Fairleigh Dickinson University’s Initiative for Patient-Centered Innovation (iPCI) 2Third Medical Innovation Impact Index Issued by Fairleigh Dickinson University’s Initiative for Patient-Centered Innovation (iPCI) 3
... thrive in today,s,competitive and changing marketplace, sales force ... doesn,t just happen. Productive,companies train, structure, deploy, and ... to ensure high success rates., Best Practices ... sales forces to evolve and mature to capture ...
... Opportunities -, BRIDGEWATER, N.J. and NEW YORK, June ... announced,its launch backed by Warburg Pincus, the leading global ... in GANIC from Warburg,Pincus Private Equity X, L.P., a ... Pharmaceuticals was founded by a highly seasoned group of ...
... a,global point-of-care diagnostic test manufacturer and wholly owned,subsidiary ... today announced,that its HemoCue Albumin 201 System is ... and monitoring microalbuminuria to be,granted a CLIA waiver ... With,the FDA CLIA waiver, non-laboratory trained physicians and ...
Cached Biology Technology:Increasing Sales Productivity Through Superior Sales Force Performance Management 2GANIC Pharmaceuticals Launched with Premier Pharmaceutical Industry Executives 2GANIC Pharmaceuticals Launched with Premier Pharmaceutical Industry Executives 3HemoCue Receives First FDA CLIA Waiver in Diagnostics Industry for Quantitative Point-of-Care Test for Microalbuminuria, a Kidney and Cardiovascular Disease Risk Marker 2HemoCue Receives First FDA CLIA Waiver in Diagnostics Industry for Quantitative Point-of-Care Test for Microalbuminuria, a Kidney and Cardiovascular Disease Risk Marker 3HemoCue Receives First FDA CLIA Waiver in Diagnostics Industry for Quantitative Point-of-Care Test for Microalbuminuria, a Kidney and Cardiovascular Disease Risk Marker 4HemoCue Receives First FDA CLIA Waiver in Diagnostics Industry for Quantitative Point-of-Care Test for Microalbuminuria, a Kidney and Cardiovascular Disease Risk Marker 5
Recombinant Viral CCI/Fc Chimera, CF...
... DeStreak Reagent, 1 ml. Improves ... gels by preventing streaking.Eliminates extra ... of proteins.Stabilizes proteins throughout entire ... well-resolved protein patterns.Ideal for both ...
LIVE/DEAD® Cell-Mediated Cytotoxicity Kit *for animal cells* *2000 assays*...
SlowFade Antifade Kit with DAPI...
Biology Products: