Navigation Links
Researchers track antibiotic-resistant strains of Salmonella from farm to fork
Date:8/29/2013

to identify antibiotic resistant strains of Salmonella Typhimurium focusing on virulence genes and novel regions of the bacteria's DNA known as clustered regularly interspaced short palindromic repeats, or CRISPRs. They report their results in the September issue of Antimicrobial Agents and Chemotherapy.

CRISPRs are present in many foodborne pathogens. The researchers demonstrated that CRISPR sequences can be used to identify populations of Salmonella with common antibiotic-resistance patterns in both animals and humans.

"Specifically, we were able to use CRISPRs to separate isolates by their propensity for resistance to seven common veterinary and human clinical antibiotics," DiMarzio said. "Our research demonstrates that CRISPRs are a novel tool for tracing the transmission of antibiotic-resistant Salmonella Typhimurium from farm to fork."

DiMarzio found that several subtypes of Salmonella Typhimurium showed up repeatedly in the frozen collection of Salmonella samples taken from cows, pigs and chickens in Penn State's Animal Diagnostic Laboratory. In this case, researchers looked at 84 unique Salmonella Typhimurium isolates collected from 2008 to 2011.

"We know those strains are widely disbursed, and the thing they have in common is that they have noticeably higher levels of antibiotic resistance," he said. "So we examined clinical samples of Salmonella taken from humans, and it turned out that we see an overlap -- the ones we see in humans are the ones we see a lot in animals. You would expect that, but it is confirmation that our method works."

DiMarzio noted that the researchers identified subsets of the overall Salmonella bacteria population that seem to be more prone to acquiring antibiotic resistance.

"Our challenge now is to learn what makes those strains different -- why do some strains acquire resistance while others don't, even though both are circulating wid
'/>"/>

Contact: A'ndrea Elyse Messer
aem1@psu.edu
814-865-9481
Penn State
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Researchers develop model of near-optimal genetic code
2. Researchers develop novel polymer to help oral medications reach the bloodstream
3. Researchers develop rapid, cost-effective early detection method for organ transplant injury
4. UTHealth, Swedish researchers uncover mystery in blot clotting disorder
5. Researchers develop software tool for cancer genomics
6. Rice, MD Anderson researchers win NIH grant to study protein networks
7. Researchers discover how inhibitory neurons behave during critical periods of learning
8. UCLA researchers invent portable device for common kidney tests
9. Harvard Stem Cell researchers create cells that line blood vessels
10. Researchers figure out why gold nanoparticles can penetrate cell walls
11. Finnish researchers develop quick test kit for detecting phenolic compounds in drinking water
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/22/2015)... May 22, 2015  NXT-ID, Inc. (NASDAQ: NXTD ) ... will be ending its promotional pricing and making the Wocket ... Laurence Savin , Head of Marketing said, "We,ve extended ... until the end of May. To get your wocket at ... we open the store on June 1, you,ll receive a ...
(Date:5/20/2015)... DUBLIN , May 20, 2015 ... Markets ( http://www.researchandmarkets.com/research/h8t4x6/5year ) has announced the ... of the Global Iris Recognition Market" ... http://photos.prnewswire.com/prnh/20130307/600769) , ,This research service analyses ... across the government and commercial sectors, ...
(Date:5/19/2015)... 19, 2015 Research ... addition of the  "Genetic Testing Market Outlook ... http://photos.prnewswire.com/prnh/20130307/600769) , ,A recent report, Genetic Testing ... of the current and future genetic testing ... their working principles and types are covered ...
Breaking Biology News(10 mins):NXT-ID, Inc Announces Retail Price For Wocket Smart Wallet And Extends Discounted Promotional Price Till End Of May 2NXT-ID, Inc Announces Retail Price For Wocket Smart Wallet And Extends Discounted Promotional Price Till End Of May 3Global Iris Recognition Market Report 2015 - 5-Year Opportunity Analysis 2Global Genetic Testing Market Outlook 2018 2
... are abdominal obesity and high levels of a type of ... a person,s risk for stroke. The potential complications are serious: ... kidney disease and stroke. Preserving the ... a type of poly-unsaturated fat thought to play an important ...
... , A variation in the gene FOXO3A has ... is found much more often in people living to 100 ... A research group in the Faculty of Medicine at the ... comparing DNA samples taken from 388 German centenarians with those ...
... 2, 2009) -- By using OP9-DL1 ... the differentiation of embryonic stem cells into mature ... issue of Cold Spring Harbor Protocols ... from Juan Carlos Ziga-Pflcker,s laboratory at the University ...
Cached Biology News:Fighting obesity and illness with a novel approach to nutrition 2Fighting obesity and illness with a novel approach to nutrition 3Living longer thanks to the 'longevity gene' 2Cold Spring Harbor Protocols features stem cell differentiation, plant RNAi methods 2
(Date:5/28/2015)... , May 27, 2015 Research and ... Jain PharmaBiotech,s new report "Neuroprotection - Drugs, ... This report describes the role of neuroprotection ... of the nervous system as well as in ... of the underlying mechanisms of damage to neural ...
(Date:5/28/2015)... May 28, 2015 BioNorth Texas ... and representing the life sciences industry in northern ... Directors meeting at The Foundry in Dallas on ... organization brought together a broad spectrum of biotech ... the organization's early successes in partnering with key ...
(Date:5/28/2015)... May 28, 2015 CD-adapco, the ... Engineering software, announced today it is joining the ... will provide state-of-the-art engineering simulation tools for analyzing ... expertise and experiences in analyzing particle flow that ... and advance the understanding of flow modeling solutions. ...
(Date:5/28/2015)... May 28, 2015 American Process ... (Oak Ridge, TN) recently signed a joint ... printing plastic resins using nanocellulose, a rapidly emerging ... 3D printing is the limited number of feedstock ... mechanical strength to printed parts for load bearing ...
Breaking Biology Technology:Global Neuroprotection Market Report 2015-2024 - Drugs, Markets and Companies 2Global Neuroprotection Market Report 2015-2024 - Drugs, Markets and Companies 3BioNorthTX Holds Inaugural Board of Directors Meeting 2BioNorthTX Holds Inaugural Board of Directors Meeting 3CD-adapco and PSRI Chartering New Course in Particle Flow Simulations 2American Process Inc. Announces Partnership with Oak Ridge National Laboratory to Make 3D Printing Plastic Resins Stronger and More Sustainable 2American Process Inc. Announces Partnership with Oak Ridge National Laboratory to Make 3D Printing Plastic Resins Stronger and More Sustainable 3
... is launched at the Cellulosic Ethanol Summit in ... ... N.Y., Oct. 15 Genencor, a division of,Danisco A/S, today ... biomass enzyme developed specifically for,second generation biorefineries. Accellerase(TM) 1000 contains ...
... China Biopharma,Inc. (OTC Bulletin Board: CBPC) announced ... Co., Ltd. ("Soonfast") has successfully,completed its trial production ... been approved in China for external use to ... Tests have shown,an inhibitory effect on the growth ...
... - Neptune Technologies &,Bioressources Inc. ("Neptune") (NASDAQ.NEPT ... of a dynamic new Scientific Advisory Board ... Neptune believes that the combined knowledge ... Advisory Board will significantly contribute to Neptune,s,scientifically ...
Cached Biology Technology:Genencor Launches First Ever Commercial Enzyme Product for Cellulosic Ethanol 2Genencor Launches First Ever Commercial Enzyme Product for Cellulosic Ethanol 3Company's Partner Completes Trial Production of a New Antiviral Medicine 2Company's Partner Completes Trial Production of a New Antiviral Medicine 3Neptune strengthens scientific operations with the appointment of a new Scientific Advisory Board 2Neptune strengthens scientific operations with the appointment of a new Scientific Advisory Board 3
... Cloning Kit, 40 reactions. Optimized for ... all PCR products with blunt or ... by offering consistently better signal-to-noise ratios ... positive clones.Amplicons generated by proof-reading thermostable ...
PCR System for increased fidelity, yield and length of PCR products. Amplifies targets up to 10 kb from human genomic DNA....
... Two separate vials containing 200 ... same sequence used as antigens for ... 160890) To be ... cyclase polyclonal antiserum (Catalog No. 160890) ...
...
Biology Products: