Navigation Links
Researchers track antibiotic-resistant strains of Salmonella from farm to fork
Date:8/29/2013

to identify antibiotic resistant strains of Salmonella Typhimurium focusing on virulence genes and novel regions of the bacteria's DNA known as clustered regularly interspaced short palindromic repeats, or CRISPRs. They report their results in the September issue of Antimicrobial Agents and Chemotherapy.

CRISPRs are present in many foodborne pathogens. The researchers demonstrated that CRISPR sequences can be used to identify populations of Salmonella with common antibiotic-resistance patterns in both animals and humans.

"Specifically, we were able to use CRISPRs to separate isolates by their propensity for resistance to seven common veterinary and human clinical antibiotics," DiMarzio said. "Our research demonstrates that CRISPRs are a novel tool for tracing the transmission of antibiotic-resistant Salmonella Typhimurium from farm to fork."

DiMarzio found that several subtypes of Salmonella Typhimurium showed up repeatedly in the frozen collection of Salmonella samples taken from cows, pigs and chickens in Penn State's Animal Diagnostic Laboratory. In this case, researchers looked at 84 unique Salmonella Typhimurium isolates collected from 2008 to 2011.

"We know those strains are widely disbursed, and the thing they have in common is that they have noticeably higher levels of antibiotic resistance," he said. "So we examined clinical samples of Salmonella taken from humans, and it turned out that we see an overlap -- the ones we see in humans are the ones we see a lot in animals. You would expect that, but it is confirmation that our method works."

DiMarzio noted that the researchers identified subsets of the overall Salmonella bacteria population that seem to be more prone to acquiring antibiotic resistance.

"Our challenge now is to learn what makes those strains different -- why do some strains acquire resistance while others don't, even though both are circulating wid
'/>"/>

Contact: A'ndrea Elyse Messer
aem1@psu.edu
814-865-9481
Penn State
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Researchers develop model of near-optimal genetic code
2. Researchers develop novel polymer to help oral medications reach the bloodstream
3. Researchers develop rapid, cost-effective early detection method for organ transplant injury
4. UTHealth, Swedish researchers uncover mystery in blot clotting disorder
5. Researchers develop software tool for cancer genomics
6. Rice, MD Anderson researchers win NIH grant to study protein networks
7. Researchers discover how inhibitory neurons behave during critical periods of learning
8. UCLA researchers invent portable device for common kidney tests
9. Harvard Stem Cell researchers create cells that line blood vessels
10. Researchers figure out why gold nanoparticles can penetrate cell walls
11. Finnish researchers develop quick test kit for detecting phenolic compounds in drinking water
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/23/2014)... EdmontonCleaning up oil sands tailings has just gotten a ... University of Alberta civil engineering professors that uses solar ... , Instead of using UV lamps as a light ... retained in tailings ponds, professors Mohamed Gamal El-Din and ... a renewable energy source treats the wastewater just as ...
(Date:9/23/2014)... more carbon than the atmosphere and small changes ... effect on atmospheric greenhouse gas concentrations. A new ... concludes that climate warming does not accelerate ... storage, despite increases in ecosystem productivity. , ... Ecologist Dr. Christian Giardina, with the agency,s Institute ...
(Date:9/23/2014)... West Orange, NJ. September 23, 2014. Kessler Foundation ... of a foot drop stimulator during a task-specific ... system. This finding indicates that applying the foot ... from this common complication of stroke. "EMG of ... utilization of a foot drop stimulator," was published ...
Breaking Biology News(10 mins):Solar energy-driven process could revolutionize oil sands tailings reclamation 2Study helps assess impact of temperature on belowground soil decomposition 2
... Consumers shouldn,t assume that, because a product is ... University of Guelph study reveals some organic pesticides ... pesticides because the organic product may require larger ... PhD candidate Christine Bahlai compared the effectiveness and ...
... that governs flower formation has been uncovered in the daisy-like ... BMC Plant Biology have published a pair of articles ... this process differs from other model plants, such as the ... Teeri, from the University of Helsinki, Finland, worked with a ...
... been puzzled by the ability of microscopic algae to grow ... essential algal nutrient. In this week,s issue of Nature, ... Riser at the University of Washington and David Karl at ... from deep water, as much as 250 meters below the ...
Cached Biology News:Organic pesticides not always 'greener' choice, study finds 2Researchers discover source of essential nutrients for mid-ocean algae 2Researchers discover source of essential nutrients for mid-ocean algae 3
(Date:9/23/2014)... , September 23, 2014 ... from Imperial Innovations, Cambridge Innovation Capital and Johnson ... clinical cancer genomics company focused on harnessing the ... improve cancer testing and treatment, today announced it ... by Imperial Innovations and including Cambridge Innovation Capital ...
(Date:9/22/2014)... YORK and SANTA CLARA, Calif. ... Corp. (NASDAQ: WBMD ), the leading source ... new WebMD/Medscape survey that provide novel insights ... in aiding diagnosis and care.  Dr. Eric Topol ... and digital medicine, who serves as both Editor-in-Chief of ...
(Date:9/22/2014)... fragments whose job it is to stop bleeding, are ... they can "feel" the physical environment around them, researchers ... respond to surfaces with greater stiffness by increasing their ... platelets and other components of the clotting system, the ... them credit for, in that they are able to ...
(Date:9/22/2014)... University of Minnesota electrical engineering researchers have developed ... time demonstrates mechanical transportation of light. The discovery ... more efficient optical devices for computation and communication. ... electrical and computer engineering assistant professor Mo Li ... published online and will appear in the October ...
Breaking Biology Technology:Inivata Raises £4m to Realise the Potential of ctDNA Analysis to Improve Cancer Treatment Through Simple Blood Tests 2Inivata Raises £4m to Realise the Potential of ctDNA Analysis to Improve Cancer Treatment Through Simple Blood Tests 3Inivata Raises £4m to Realise the Potential of ctDNA Analysis to Improve Cancer Treatment Through Simple Blood Tests 4WebMD/Medscape Digital Technology Survey Reveals Unique Insights Into How Patients and Physicians Perceive the Role, Potential and Risks Associated with Digital Health Technologies 2WebMD/Medscape Digital Technology Survey Reveals Unique Insights Into How Patients and Physicians Perceive the Role, Potential and Risks Associated with Digital Health Technologies 3WebMD/Medscape Digital Technology Survey Reveals Unique Insights Into How Patients and Physicians Perceive the Role, Potential and Risks Associated with Digital Health Technologies 4Platelets modulate clotting behavior by 'feeling' their surroundings 2Engineers show light can play seesaw at the nanoscale 2
... April 20 Shire plc (LSE: SHP,NASDAQ: SHPGY ), the global ... , , Results press release will be issued at: ... Investor conference call time: ... EDT, , Live conference call for investors: , ...
... Mass. April 20 Advanced Instruments, ... Multi-Sample Osmometer as the first true automation-friendly osmometer ... Multi-Sample Osmometer is specifically designed for ... osmolality testing in the biopharmaceutical laboratory," said Kelly ...
... Inc., a development-stage pharmaceutical company discovering and developing ... James D. Thompson, Ph.D., Vice President, Pharmaceutical Development, ... at this year,s American Society for Pharmacology and ... place from April 18-22, 2009 in New Orleans. ...
Cached Biology Technology:Shire plc: First Quarter 2009 Results Date Notification - April 30, 2009 2Advanced Instruments Introduces 2020-BIO Multi-Sample Osmometer as First True Automation-Friendly Osmometer for the Biopharmaceutical Industry 2Advanced Instruments Introduces 2020-BIO Multi-Sample Osmometer as First True Automation-Friendly Osmometer for the Biopharmaceutical Industry 3Quark Pharmaceuticals to Present at American Society for Pharmacology and Experimental Therapeutics Annual Meeting 2Quark Pharmaceuticals to Present at American Society for Pharmacology and Experimental Therapeutics Annual Meeting 3
... clone d1-174 GenBank Accession Number : ... N-terminal tagged fusion protein corresponding to full ... Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium ... 30% Quality Assurance: routinely evaluated by immunoblot ...
Rat CXCL7/Thymus Chemokine-1 DuoSet Economy Pack, 45 Plate...
Recombinant Rat Fas Ligand/TNFSF6...
FGF Receptor 1 Antibody...
Biology Products: