Navigation Links
Researchers study sleep apnea and lack of oxygen
Date:10/4/2010

COLUMBIA, Mo. According to the National Heart, Lung and Blood Institute, the average sleep apnea sufferer stops breathing and loses oxygen between five and 30 times a night. This lack of oxygen leads to a host of complications, including high blood pressure, vascular disease, an abnormal heart rhythm, or even a fatal cardiac event. Now, a team of University of Missouri researchers is exploring the changes in distinct brain regions that contribute to these symptoms in hopes of combating this common health issue.

Sleep apnea occurs when the muscles in the back of the throat relax during sleep, leading the airway to narrow or close. It's estimated that 12 million Americans are affected by sleep apnea, but it's widely believed that the issue is under reported. There are no blatant signs or blood tests to diagnose the disrupted sleep. Most cases of sleep apnea are discovered when a partner notices an increase in snoring, or when the sufferer indicates daytime fatigue and sleepiness.

To learn more about sleep apnea, the National Institutes of Health awarded University of Missouri researchers a $2.83 million multi-investigator grant to continue work on neurohumoral control of the circulation and breathing studying how the brain responds to hypoxia, or the lack of oxygen. The team includes Eileen Hasser, professor in the Department of Biomedical Sciences and adjunct professor of medical pharmacology and physiology; Cheryl Heesch, professor in the Department of Biomedical Sciences; and David Kline, assistant professor in the Department of Biomedical Sciences.

The researchers use an experimental model of lab rats that produces traits that mimic periodic sleep apnea. Using state-of-the-art techniques and equipment in the MU Dalton Cardiovascular Research Center, the researchers are able to identify specific cells and pathways within the brain that are involved in responses to hypoxia. Researchers hope the information can be used to develop drugs or procedures to correct or slow the dangerous effects of sleep apnea.

"Working together, we each bring different skills and ways of looking at the problem, which increases our ability to answer the important questions in this field," Hasser said.

While only in the first year of the four-year grant, the researchers have already advanced knowledge on how the brain adapts to diminished oxygen. Results of their initial experiments were recently published in the scientific journal, Neuroscience.


'/>"/>

Contact: Steven Adams
AdamsST@missouri.edu
573-882-8353
University of Missouri-Columbia
Source:Eurekalert

Related biology news :

1. Bonn researchers use light to make the heart stumble
2. Researchers engineer adult stem cells that do not age
3. OU researchers selected by Navy
4. Researchers find first genetic evidence for loss of teeth in the common ancestor of baleen whales
5. McLean Hospital researchers awarded $1.9 9 million grant for stem cell, blood research
6. WSU researchers taking sustainability of organic farming to new level
7. Purifying proteins: Rensselaer researchers use NMR to improve drug development
8. Smithsonian researchers find differences between Galapagos and mainland frigatebirds
9. Iowa State, Ames Lab researchers identify structure that allows bacteria to resist drugs
10. Vitamin C rapidly improves emotional state of acutely hospitalized patients, say LDI researchers
11. BUSM researchers to study vitamin D production in fat malabsorption patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/19/2017)... and PUNE, India , January 19, 2017 /PRNewswire/ ... titled, "Global Biometric Sensor Market, Opportunities and Forecast, 2014 - 2022," the ... at a CAGR of 9.6% from 2016 to 2022. In 2015, ... to high-level security for both public and private sectors. ... ...
(Date:1/13/2017)... , Jan. 13, 2017 Sandata ... solutions for the homecare industry, including Electronic Visit ... industry expert, Justin Jugs, as Senior Vice President ... than 15 years of homecare experience to Sandata, ... developing strategic plans to align Sandata,s suite of ...
(Date:1/11/2017)... Intoxalock, a leading ignition interlock provider, has ... patent-pending calibration device. With this new technology, Intoxalock is ... data logs and process repairs at service center locations, ... drunk driving through the application of cutting-edge technologies is ... also for the customer who can get back on ...
Breaking Biology News(10 mins):
(Date:1/24/2017)... India , January 23, 2017 ... Mouse Model Market by Type (Genetic, Cell-based (CD34, PBMC, ... & End User (Pharmaceutical & Biotech Companies, CRO) - ... studies the global Humanized Mouse Model Market for the ... expected to reach USD 116.0 Million by 2021 from ...
(Date:1/24/2017)... Inc. (NYSE: BIOA ) today announced that ... & Renshaw, a unit of H.C. Wainwright ... of several underwriters, under which the underwriters have agreed ... of 2,105,264 shares of common stock of the Company, ... shares of common stock of the Company with an ...
(Date:1/23/2017)... BOONTON, N.J. , Jan. 23, 2017   ... a feasibility study agreement with Sanofi to ... molecule delivery platform, Peptelligence™, to develop an oral formulation ... Joel Tune , Chief Executive Officer and ... Sanofi is further validation of the tremendous value our ...
(Date:1/23/2017)... ... January 23, 2017 , ... Calvert Labs, ... Preclinical Safety and Senior Director, Safety Pharmacology. Dr. Thomas earned his M.Sc. ... Dr. Thomas’ career as an academic and industry preclinical drug developer spans more ...
Breaking Biology Technology: