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Researchers show how 1 gene becomes 2 (with different functions)
Date:1/12/2011

ice-binding functions. This suggests that somehow the SAS protein (which is not secreted) acted within the cell to disrupt the growth of ice.

This could have occurred "in the early developmental stages of the fish," Cheng said, since the eggs are spawned into a cold environment and would benefit from even the modest antifreeze capabilities of the SAS protein.

Later, after the SAS gene was duplicated and the AFP gene went on its own evolutionary path, Cheng said, the antifreeze protein appears to have evolved into a secreted protein, allowing it to disrupt ice formation in the bloodstream and extracellular fluid, where it would be of most benefit to the adult fish.


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Contact: Diana Yates
diya@illinois.edu
217-333-5802
University of Illinois at Urbana-Champaign
Source:Eurekalert  

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