Navigation Links
Researchers show how 1 gene becomes 2 (with different functions)
Date:1/12/2011

d signal sequence also appears in the AFP III genes. Unlike the SAS enzymes, which remain inside the cell, the AFP III proteins are secreted into the blood or extracellular fluid, where they can more easily disrupt the growth of invading ice crystals.

"This basically demonstrates how something that 'lives' inside the cell can acquire this new functionality and get moved out into the bloodstream to do something else," Cheng said.

Further analysis revealed that the SAS proteins function as enzymes but also have modest ice-binding capabilities. This finding supports a decades-old hypothesis that states that when a single gene begins to develop more than one function, duplication of that gene could result in the divergent evolution of the original gene and its duplicate.

The new finding also supports the proposed mechanism, called "escape from adaptive conflict," by which this can occur. According to this idea, if a gene has more than one function, mutations or other changes to the gene through natural selection that enhance one function may undermine its other function.

"The original enzyme function and the emerging ice-binding function of the ancestral SAS molecule might conflict with each other," Cheng said. When the SAS-B gene became duplicated as a result of a copying error or some other random event in the cell, she said, then each of the duplicate genes was freed from the conflict and "could go on its own evolutionary path."

"This is the first clear demonstration with strong supporting molecular and functional evidence of escape from adaptive conflict as the underlying process of gene duplication and the creation of a completely new function in one of the daughter copies," Cheng said. "This has not been documented before in the field of molecular evolution."

Cheng said that even before the gene for the secreted antifreeze protein was formed, the original SAS protein appears to have had both the enzymatic and
'/>"/>

Contact: Diana Yates
diya@illinois.edu
217-333-5802
University of Illinois at Urbana-Champaign
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. NC State researchers get to root of parasite genome
2. Researchers find animal with ability to survive climate change
3. Researchers find an essential gene for forming ears of corn
4. Researchers note differences between people and animals on calorie restriction
5. Researchers study acoustic communication in deep-sea fish
6. Researchers discover that growing up too fast may mean dying young in honey bees
7. Researchers study how pistachios may improve heart health
8. UI researchers find potentially toxic substance present in Chicago air
9. Researchers develop new self-training gene prediction program for fungi
10. Case Western Reserve University researchers track Chernobyl fallout
11. Childrens National researchers develop novel anti-tumor vaccine
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Researchers show how 1 gene becomes 2 (with different functions)
(Date:8/10/2015)... and TELTOW, Germany , ... Instruments (SMI), a world leader in Eye Tracking ... completion of its OEM Eye Tracking Platform for integration ... Tracking Platform contains reference designs for seamless integration of ... systems, virtual reality HMDs and augmented reality smart glasses. ...
(Date:8/6/2015)... Germany , August 6, 2015 ... (SMI) shows the world,s first Eye Tracking ... Epson,s Moverio BT-200 see-through head mounted display and on ... unprecedented quality and efficiency is brought to personalized visualization ... the first time, professionals and researchers can integrate gaze, ...
(Date:8/5/2015)... New York , August 5, 2015 ... market report titled "Facial Recognition Market - Global Industry ... 2022", the global market for facial recognition is forecast ... is driven by increased demand for surveillance systems by ... the rising number of crimes and terrorist activities across ...
Breaking Biology News(10 mins):SMI Completes OEM Eye Tracking Platform to Cover All Consumer Displays 2SMI Completes OEM Eye Tracking Platform to Cover All Consumer Displays 3SMI Shows First Eye Tracking Upgrade for Augmented Reality Glasses 2SMI Shows First Eye Tracking Upgrade for Augmented Reality Glasses 3Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 2Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 3Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 4Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 5Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 6
... 12-week treatment of the fermented soy germ-based nutritional supplement ... and improved vascular stiffness, all factors that occur as ... study reported in a poster at the Women,s Health ... the first to provide evidence that a daily supplement ...
... of Cincinnati undergraduate student and two team members, there,s a ... in continuously recording the habits of snakes. This small-scale ... on snakes, since the LAT devices were originally developed for ... to measure temperature and pressure measuring pressure translates into ...
... -- Research from a Kansas State University professor may ... or to study neurological disorders. Mark Weiss, professor ... spinal cord injury or diseases such as Parkinson,s disease. ... and regenerative medicine -- a type of research that ...
Cached Biology News:Soy-based S-equol supplement reduces metabolic syndrome risk factors 2Soy-based S-equol supplement reduces metabolic syndrome risk factors 3UC research: Tracking Lake Erie water snake in fight against invasive fish 2UC research: Tracking Lake Erie water snake in fight against invasive fish 3Genetic research develops tools for studying diseases, improving regenerative treatment 2
(Date:8/28/2015)... ... 28, 2015 , ... Riordan-McKenna Institute founders, stem ... that the use of sterile, dehydrated amniotic tissue AlphaPATCHâ„¢ developed by Amniotic ... surgical knee wound. , The case involved a 78-year-old male, who presented with ...
(Date:8/27/2015)... , Aug. 27, 2015 /PRNewswire/ - Portage Biotech ... PBT.U), and Biohaven Pharmaceutical Holding Company Limited (Biohaven), ... Phase I study of BHV-0223, a glutamate modulating ... regarding BHV-0223 and recently obtained clearance from the ... with human testing. Portage holds 54% equity interest ...
(Date:8/27/2015)... YORK , August 27, 2015 ... enhancing image processing functions in the human vision system, announced ... point guard Chris Paul to develop ... players who want to improve their real-life on-court performance. ... the court, whether it is shooting a ball or blocking ...
(Date:8/26/2015)... KS (PRWEB) , ... August 26, 2015 , ... ... Biologic Solutions, announces today that a second US laboratory is to open in ... accordance with the continued partnership and long-term growth of research and development through ...
Breaking Biology Technology:Dallas-Fort Worth Stem Cell Researchers Use Amniotic Tissue To Successfully Treat Non-Healing Surgical Wound 2Dallas-Fort Worth Stem Cell Researchers Use Amniotic Tissue To Successfully Treat Non-Healing Surgical Wound 3Dallas-Fort Worth Stem Cell Researchers Use Amniotic Tissue To Successfully Treat Non-Healing Surgical Wound 4Portage's Biohaven doses first human subject in Phase 1 trial with lead drug candidate BHV-0223 2Portage's Biohaven doses first human subject in Phase 1 trial with lead drug candidate BHV-0223 3Portage's Biohaven doses first human subject in Phase 1 trial with lead drug candidate BHV-0223 4Eight-Time All-Star Chris Paul and GlassesOff Partner to Develop Innovative Mobile App Designed to Improve On-Court Performance 2Eight-Time All-Star Chris Paul and GlassesOff Partner to Develop Innovative Mobile App Designed to Improve On-Court Performance 3MediVet Biologics Animal Health Secures Additional Laboratory Facility in Manhattan, Kansas 2MediVet Biologics Animal Health Secures Additional Laboratory Facility in Manhattan, Kansas 3
... ... Applications, ST. LOUIS and ... Sangamo BioSciences, Inc.,(Nasdaq: SGMO ) today announced a research and ... the use of its,proprietary zinc finger nuclease (ZFN) technology to develop ...
... require a transparent conductive layer with a high work ... an organic layer to produce more light. , ... on Science and Technology of Synthetic Metals in Brazil ... A balanced injection of positive and negative charge carriers ...
... SAN MARINO, Calif., July 8 Epeius Biotechnologies,Corporation ... Drug,Designation by the U.S. Food and Drug Administration ... criteria, including the rarity,seriousness, and current lack of ... scientific and medicinal merit of Rexin-G, the,granting of ...
Cached Biology Technology:Sangamo BioSciences and Sigma-Aldrich Announce Research and License Agreement With Roche for the Use of ZFN Technology for Generation of Transgenic Animals 2Sangamo BioSciences and Sigma-Aldrich Announce Research and License Agreement With Roche for the Use of ZFN Technology for Generation of Transgenic Animals 3Sangamo BioSciences and Sigma-Aldrich Announce Research and License Agreement With Roche for the Use of ZFN Technology for Generation of Transgenic Animals 4Sangamo BioSciences and Sigma-Aldrich Announce Research and License Agreement With Roche for the Use of ZFN Technology for Generation of Transgenic Animals 5Research helps understand factors that influence efficiency of organic-based devices 2Research helps understand factors that influence efficiency of organic-based devices 3Epeius Biotechnologies' Tumor-Targeted Rexin-G Receives FDA Orphan Drug Designation for the Treatment of Osteosarcoma 2