Navigation Links
Researchers 'see' structure of open nicotinic acetylcholine ion channels
Date:4/7/2008

nnels are meant to be quick, he said. If they are too slow, we have disease.

Grosman said that the approach developed in his lab is the first to allow scientists to infer the structure of an ion channel in its open conformation as it functions in a living cell.

I know when the protein is open, because in single-molecule experiments the distinction between open and closed conformations is simple; the channel either passes a current or not, he said.

In a living cell the protein responds, in measurable ways, to changes in its structure and environment, he said. Its not frozen at super low temperatures. Its not in a crystalline lattice. The cells are alive at the beginning of the experiment and when we finish the experiment, the cells keep living.


'/>"/>

Contact: Diana Yates
diya@uiuc.edu
217-333-5802
University of Illinois at Urbana-Champaign
Source:Eurekalert  

0

GOOD

Page: 1 2 3

Related biology news :

1. Researchers identify proteins involved in new neurodegenerative syndrome
2. Texas researchers and educators head for Antarctica
3. MGH researchers describe new way to identify, evolve novel enzymes
4. University of Pennsylvania researchers develop formula to gauge risk of disease clusters
5. U of MN researchers discover noninvasive diagnostic tool for brain diseases
6. U of Minnesota researchers discover noninvasive diagnostic tool for brain diseases
7. Researchers discover new strategies for antibiotic resistance
8. Researchers find new taste in fruit flies: carbonated water
9. Binghamton University researchers investigate evolving malaria resistance
10. UIC researchers find promising new targets for antibiotics
11. Researchers develop simple method to create natural drug products

Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Researchers 'see' structure of open nicotinic acetylcholine ion channels
Researchers 'see' structure of open nicotinic acetylcholine ion channels
(Date:11/30/2009)... , VILNIUS, Lithuania, Nov. 30 /PRNewswir....com ), a provider of high-precision biometric ide...rades in the company,s core product line: VeriLoo...ecognition and MegaMatcher 3.1 SDK for large-sca...ification systems (AFIS). Expanded capabilities in...
(Date:11/26/2009)...rhead sharks are some of the Ocean,s most distinct...hey have this strange head shape, says Michelle M...le reason is the shark,s vision. ,Perhaps their vi...hape, says McComb, giving the sharks excellent st...g to McComb, there were two schools of thought on ...
(Date:11/26/2009)...gists have at last worked out a way of using recor...f bird populations. This is the first time sound r...ated into accurate estimates of bird species, popu...e British Ecological Society,s Journal of Applied...d lead to a major advance in our ability to monito...
Breaking Biology News(10 mins):New VeriLook 4.0 for Biometric Facial Recognition and MegaMatcher 3.1 for Multi-biometric Applications Are Now Available 2New VeriLook 4.0 for Biometric Facial Recognition and MegaMatcher 3.1 for Multi-biometric Applications Are Now Available 3Wide heads give hammerheads exceptional stereo view 2Ecologists sound out new solution for monitoring cryptic species 2Plastics that convert light to electricity could have a big impact 13366 1Plastics that convert light to electricity could have a big impact 13366 2Plastics that convert light to electricity could have a big impact 13366 3Avipaxin Is First Entrant in Medical Arsenal for Neuro Endocrine Immune Connection 28C 29 Product and Testing Protocols 53679 1Avipaxin Is First Entrant in Medical Arsenal for Neuro Endocrine Immune Connection 28C 29 Product and Testing Protocols 53679 2Pharmacy Compounds Liquid Mupirocin for the Chronic Sinusitis Patient 13365 1Pharmacy Compounds Liquid Mupirocin for the Chronic Sinusitis Patient 13365 2
...attle the tiny, red wormlike insects that nibble o...de, but the Hessian fly larvae that survive eventu...Purdue University and USDA-Agriculture Research Se...identified Hessian fly genes that nullify toxins t...hing larvae. The researchers report their findings...
...ntain high levels of action, such as Unreal Tourna...hers at the University of Rochester have shown tha...ours a day over the course of a month improved by ...ers presented in clutter—a visual acuity test simi... , In essence, playing video game improves your ...
...am led by researchers from the National Human Geno...l Institutes of Health (NIH), has identified a gen...size in dogs. The findings appear in the April 6, ...cation and characterization of a key genetic varia...rticularly exciting because the underlying gene is...
Other Biology News:Scientists find genes involved in the battle between Hessian flies and wheat 2Scientists find genes involved in the battle between Hessian flies and wheat 3Action video games sharpen vision 20 percent 2Researchers identify gene involved in dog size 2Researchers identify gene involved in dog size 3Researchers identify gene involved in dog size 4
(Date:12/1/2009)... iCardiac now provides services to three o..., Rochester, NY (PRWEB) De...lobal leader in advanced cardiac core lab services...pharmaceutical company has selected iCardiac as a ...ac will provide Highly Automated QT(sm) and Dynami...
(Date:12/1/2009)... Michael R. Drapp, a 34-year veteran of th...ade; Technologies, a business development and inte...e emerging nanotechnology space. The company also... as a nanotechnology incubator. , ... Michael R. Drapp , a 34-year veteran of the high-...
(Date:11/30/2009)...ss November 30, 2009 An international team of ap..., and ETH Zrich have demonstrated compact, multibe...visible part of the light spectrum (infrared). By ...of a well-defined wavelength. The innovative multi...ated to remote chemical sensing pollution monitori...
(Date:11/30/2009)...INGTON, Minn., Nov. 30 Acuo Techno...ge management software, data migration tools and s...ospitals and Clinics for a new Vendor Neutral Arch...ge across the Allina network of hospitals, clinics...ased on the Acuo Technologies DICOM Services Grid(...
Breaking Biology Technology:Another Top Five Pharmaceutical Company Selects iCardiac as Preferred Provider of ECG Core Lab Services 2Silicon Valley Veteran Launches New Venture on the “nanoEdge” of the Emerging Nanotechnology Revolution 2Silicon Valley Veteran Launches New Venture on the “nanoEdge” of the Emerging Nanotechnology Revolution 3Silicon Valley Veteran Launches New Venture on the “nanoEdge” of the Emerging Nanotechnology Revolution 4Scientists demonstrate multibeam, multi-functional lasers 2Acuo Technologies Announces Contract for Vendor Neutral Archive With Allina Hospitals and Clinics 2Acuo Technologies Announces Contract for Vendor Neutral Archive With Allina Hospitals and Clinics 3
...D CITY, Calif., Feb. 3 Genomic Health,Inc. (Nasda...usiness progress for,the fourth quarter and year e...e fourth quarter of 2008 increased to $31.2 millio...r of 2007. Product revenue,from the Oncotype DX(R...rth,quarter of 2008, an increase of 60 percent, co...
...D, Fla., Feb. 3 .decimal, Inc. announced today th...nt Centers, Inc. to supply,patient-specific device...,Oklahoma. , (Logo: http://www.newscom.com/c...l is excited to have a formal agreement signed wit... of custom, patient-specific devices,utilizing our...
... Mass., Feb. 3 Abt Associates announced that Rick...l Associate. After a brief orientation to the fir...,s education work in September 2009. Dr. Takai br...gn and management of federal evaluation studies in...recently, Dr. Takai served as Associate Commission...
Other Biology Technology:Genomic Health Announces Fourth Quarter and Year-End 2008 Financial Results and Business Progress, Provides 2009 Financial Guidance 2Genomic Health Announces Fourth Quarter and Year-End 2008 Financial Results and Business Progress, Provides 2009 Financial Guidance 3Genomic Health Announces Fourth Quarter and Year-End 2008 Financial Results and Business Progress, Provides 2009 Financial Guidance 4Genomic Health Announces Fourth Quarter and Year-End 2008 Financial Results and Business Progress, Provides 2009 Financial Guidance 5Genomic Health Announces Fourth Quarter and Year-End 2008 Financial Results and Business Progress, Provides 2009 Financial Guidance 6Genomic Health Announces Fourth Quarter and Year-End 2008 Financial Results and Business Progress, Provides 2009 Financial Guidance 7Genomic Health Announces Fourth Quarter and Year-End 2008 Financial Results and Business Progress, Provides 2009 Financial Guidance 8Genomic Health Announces Fourth Quarter and Year-End 2008 Financial Results and Business Progress, Provides 2009 Financial Guidance 9ProCure Signs Agreement with .decimal, Inc. to Purchase Patient-Specific Devices for Its Proton Therapy Center in Oklahoma City 2Dr. Ricky Takai, Expert in Designing and Managing Federal Evaluation Studies in Education, Joins Abt Associates 2
...tion Kit (Catalog number SCR004) is a specific and...S cell differentiation by the determination of AP ...the monoclonal antibodies TRA-2-49 (Catalog Number...hich permit the detection of Liver / Bone / Kidney...
Complete 2 channel polarographic oxygen monitoring system from Instech Solomon
Freund's Incomplete Adjuvant, Modified from Calbiochem
Gey's Balanced Salt Solution (GBSS) from Sigma-Aldrich
Biology Products: