Navigation Links
Researchers' new recipe cooks up better tissue 'phantoms'
Date:11/30/2011

WASHINGTON, Nov. 30The precise blending of tiny particles and multicolor dyes transforms gelatin into a realistic surrogate for human tissue. These tissue mimics, known as "phantoms," provide an accurate proving ground for new photoacoustic and ultrasonic imaging technologies. "The ability to provide phantoms that are capable of mimicking desired properties of soft tissue is critical to advance the development of new, more-accurate imaging technologies," said Stanislav Emelianov of the University of Texas at Austin and co-author of a paper appearing in the Optical Society's (OSA) open-access journal Biomedical Optics Express that describes an improved method for fabricating tissue phantoms.

Ultrasonic imaging uses high-frequency acoustic pulses to probe the structure of tissues. Another technique, photoacoustic imaging, uses low-energy laser pulses to create tiny acoustic waves that propagate through tissues. Certain tissues and materials (e.g. blood, nanoparticles used in certain tests, and fluorescent dyes), however, readily absorb the optical wavelengths typically used in photoacoustic imaging. By combining acoustic and photoacoustic imaging techniques, it's possible to create a more comprehensive picture of soft tissues. Designing effective imaging devices that can concurrently harness these two technologies, however, requires true-to-life phantoms. Emelianov and his colleagues have met this need by designing and testing a novel combination of additives that enable gelatin to acquire acoustical and optical properties that accurately match soft tissue in humans.

To match the acoustical properties, the researchers added 40-micron silica spheres to the gelatin. These particles help scatter the acoustical signal, matching the behavior of normal tissue. An emulsion of fat was also used to attenuate, or absorb, the acoustical signal. The fat additive also enhanced optical scattering of the mixture. The final ingredients were commercial dyes India ink, Direct Red 81, and Evans blue which provided similar optical absorption to natural tissues.

"These combined characteristics are of particular value because of the growing use of combined ultrasonic and photoacoustic imaging in clinical and preclinical research," says Emelianov. "Furthermore, there has been increased interest in utilizing these combined technologies in clinical applications, such as vascular imaging, lymph node assessment, and atherosclerotic plaque characterization."


'/>"/>

Contact: Angela Stark
astark@osa.org
202-416-1443
Optical Society of America
Source:Eurekalert

Related biology news :

1. BUSM researchers develop blood test to detect membranous nephropathy
2. WSU researchers use a 3-D printer to make bone-like material
3. Abstinence-only education does not lead to abstinent behavior, UGA researchers find
4. Body rebuilding: Researchers regenerate muscle in mice
5. UCLA researchers engineer blood stem cells to fight melanoma
6. BWH researchers develop a vaccine prototype stronger than traditional vaccines
7. The immune system has protective memory cells, researchers discover
8. Researchers awarded $3.2 million from NIH to pioneer advanced biomolecule discovery technology
9. 3 researchers in the Amazon clear up doubts as to the benefits of ecotourism
10. Effects of climate change to further degrade fisheries resources: UBC researchers
11. UGA researchers develop super yeast that turns pine into ethanol
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/3/2016)... --> --> Fourth quarter 2015:   ... compared with fourth quarter of 2014. Gross margin was 46% ... Earnings per share increased to SEK 6.39 (loss: 0.49). ... , --> --> January ... (233.6), up 1,142% compared with 2014. Gross margin was 43% ...
(Date:2/2/2016)... Feb. 2, 2016 This BCC Research ... market by reviewing the recent advances in high ... drive the field forward. Includes forecast through 2019. ... the challenges and opportunities that exist in the ... solution developers, as well as IT and bioinformatics ...
(Date:2/1/2016)... Rising sales of consumer electronics ... intuitive gesture control market size ... consumer electronics coupled with new technological advancements to drive ... through 2020   --> ... advancements to drive global touchfree intuitive gesture control market ...
Breaking Biology News(10 mins):
(Date:2/10/2016)... , Febr. 10, 2016 /PRNewswire/ - BioAmber Inc. (NYSE: ... pleased to announce that Mitsui & Co. Ltd., its ... succinic acid plant, is investing an additional CDN$25 million ... increasing its stake from 30% to 40%.  Mitsui will ... bio-succinic acid produced in Sarnia , ...
(Date:2/10/2016)... WASHINGTON , Feb.10, 2016 ASAE is ... and Association Management Companies (AMC) the option of joining ... flat annual fee determined by staff size, every employee ... to join ASAE and reap all available member benefits.   ... CAE. "Our new organizational membership options will allow organizations ...
(Date:2/10/2016)... 2016  Matchbook, Inc., a company specializing in ... companies, announced today the appointment of Jim ... brings nearly 25 years of experience in supply ... nearly two decades in executive level roles as ... Genzyme and, most recently headed global logistics and ...
(Date:2/10/2016)... Charlotte, NC (PRWEB) , ... February 10, 2016 ... ... highly anticipated expansion to their comprehensive training and support program, Sonalinkā„¢ remote monitoring. ... Sonablate® HIFU procedures performed on Friday, February 5th, connecting Dr. Samuel Peretsman to ...
Breaking Biology Technology: