Navigation Links
Researchers join forces to cure deadly childhood disease
Date:5/3/2011

ST. LOUIS -- The Center for World Health and Medicine at Saint Louis University and the Institute for OneWorld Health have established a joint research agreement to develop new drugs to combat diarrhea, which is the second leading cause of death worldwide in children under age 5.

Each year more than two million children in developing countries die from diarrheal diseases, which are caused by a wide range of bacterial, parasitic and viral pathogens. These organisms can be particularly virulent in the developing world, which is plagued by poor sanitation, unclean water, malnutrition and a lack of knowledge about how to prevent the illnesses.

Diarrhea is frequently a symptom of another disease, such as cholera and rotavirus, and turns deadly in children who rapidly lose body fluids, become severely dehydrated and go into shock.

"When children in St. Louis, Mo., develop severe diarrhea and become lethargic, their parents take them to the emergency room, where they are given IV fluids," said Peter Ruminski, executive director of the Center for World Health and Medicine.

"Places like rural Sub-Saharan Africa or Haiti lack adequate sanitation and access to clean water and don't have the same infrastructure that we have. Families there are not as readily able to hop in their vehicles, drive to the hospital and get hooked up to an IV to replenish vital body fluids. So if we can come up with a therapy to reduce fluid loss and get children through the acute attack phase of their diarrheal illness, we'll have an immediate effect on the number of children who die. Our goal is to save lives."

The collaboration between the Center for World Health and Medicine and the Institute for OneWorld Health (iOWH) aims to develop safe and effective anti-secretory drugs, which inhibit the loss of fluid in the intestine regardless of the root cause of the problem. These drugs are intended to be used as an adjunct to oral rehydration therapy.
'/>"/>

Contact: Nancy Solomon
solomonn@slu.edu
314-977-8017
Saint Louis University
Source:Eurekalert

Page: 1 2

Related biology news :

1. NC State researchers get to root of parasite genome
2. Researchers find animal with ability to survive climate change
3. Researchers find an essential gene for forming ears of corn
4. Researchers note differences between people and animals on calorie restriction
5. Researchers study acoustic communication in deep-sea fish
6. Researchers discover that growing up too fast may mean dying young in honey bees
7. Researchers study how pistachios may improve heart health
8. UI researchers find potentially toxic substance present in Chicago air
9. Researchers develop new self-training gene prediction program for fungi
10. Case Western Reserve University researchers track Chernobyl fallout
11. Childrens National researchers develop novel anti-tumor vaccine
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2014)... , Dec. 18, 2014 Research and Markets ... the "iPhone 5S Fingerprint Sensor - Apple/AuthenTec TMDR92 ... offering. http://photos.prnewswire.com/prnh/20130307/600769 ... Apple introduced the fingerprint reading feature with the iPhone ...
(Date:12/19/2014)... 2014   LaunchKey , the first decentralized mobile authentication ... of Things era, today announced the close of $3 ... led by Metamorphic Ventures with participation from ENIAC Ventures, ... others.  LaunchKey has raised $4 million to date, and ...
(Date:12/17/2014)... YORK , Dec. 15, 2014  HITLAB SM ... (GCP) audit to confirm its adherence to current U.S. ... HITLAB to conduct regulated smart device and smart phone ... and research quality. "HITLAB is determined to ...
Breaking Biology News(10 mins):iPhone 5S Fingerprint Sensor - Apple/AuthenTec TMDR92 & Sapphire - Technology Report 2LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 2LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 3HITLAB Completes GCP Audit for FDA Smart Device & App Compliance 2
... available in German . , Helmholtz Zentrum ... European Union, has been expanded to include six partners from ... partners will join the effort of the other 22 members ... improve open access to high-quality mouse models. Animal models have ...
... Energy (DOE) Joint Genome Institute (JGI) now has a ... 13th Annual Applied Ergonomics Conference held March 22-25, 2010 ... highlights ergonomic innovations from institutions and multinational corporations. The ... for the Ergonomic Program Improvement Initiatives category. Ergonomics ...
... preliminary study by New Zealand company Plant & Food ... breathing in some types of asthma. Researchers found ... lung inflammation with a multi-action assault in allergy-induced asthma. ... the natural defence mechanisms in lung tissue by both ...
Cached Biology News:Biomedical research infrastructure goes global: EU consortium Infrafrontier has new partners 2Breathe easy: A natural fruit compound may help asthma 2
(Date:1/23/2015)... BioPharma Inc. (NASDAQ: ARRY ) today announced ... Pharma AG to acquire worldwide rights to encorafenib (LGX818), ... agreement is conditional on the closing of transactions announced by ... are expected to close in the first half of ...
(Date:1/22/2015)... 22, 2015 Shimadzu Scientific Instruments ... multipurpose UV-visible spectrophotometer. Offering wavelength scanning from 190 ... ideal for applications in a variety of industries, ... The user-friendly UV-1280 enables intuitive operation, while the ...
(Date:1/22/2015)... , Jan. 22, 2015  Transwestern | RBJ today announces the ... office space for Shire a leading biopharmaceutical company, at Two ... | RBJ,s Robert Richards , president, and Brian ... for the entire five-floor building at 95 Hayden Ave. ...
(Date:1/22/2015)... Protocol Networks brings independent technology consulting ... brand-neutral, independent consultants, Protocol Networks has recently announced its ... the years, his company has attracted several clients in ... as well as others. With the success of these ...
Breaking Biology Technology:Array Announces Agreement To Acquire ENCORAFENIB (LGX818) 2Array Announces Agreement To Acquire ENCORAFENIB (LGX818) 3Array Announces Agreement To Acquire ENCORAFENIB (LGX818) 4Array Announces Agreement To Acquire ENCORAFENIB (LGX818) 5Array Announces Agreement To Acquire ENCORAFENIB (LGX818) 6Array Announces Agreement To Acquire ENCORAFENIB (LGX818) 7Shimadzu’s New Monitored Single-Beam UV-Vis Spectrophotometer Offers Comprehensive Measurement Options in a Compact Body 2Transwestern?RBJ Advises Shire in 202,000 SF Lease, Creating Boston's Largest Suburban Biotech Campus 2Protocol Networks Brings Independent Technology Consulting to the Constitution State 2
... , , , , , , ... To extract RNA from washed and pelleted cultured cells, add 200 , ... Isothiocyanate, 25 mM Sodium Citrate, pH 7.0, 1 M b-Mercaptoethanol) , ... 6 cells. , To directly extract RNA from cultured ...
... , , , Note: Genomic DNA is fragile. High molecular ... large-bore pipet tips or equipment when , pipetting genomic DNA. Do ... Place a 1 cm tail sample into a 1.5 ml ... at 20C. To minimize possible cross-contamination, , ...
... , , , , , , ... the , isolation of total RNA from cell and ... method, because the entire aqueous phase can be recovered , ... involved in RNA isolation with TRIzol Reagent and Phase Lock Gel-Heavy. ...
Cached Biology Technology:Total RNA Isolation Protocol 1,2,3 2Total RNA Isolation Protocol 1,2,3 3Mouse Tail Genomic DNA Isolation Protocol(1) 2Protocol for RNA Isolation Using TRIzol Reagent with Phase Lock , Gel-Heavy 2Protocol for RNA Isolation Using TRIzol Reagent with Phase Lock , Gel-Heavy 3
... organic acid analysis standard is ... organic salts; molecular weights range ... standard is provided for use ... and the organic acid analysis ...
Compound(s) tested through a broad panel of 38 ligand binding and enzyme assays targeting the Central Nervous System. Used to determine selectivity and potential CV/Renal liabilities of compounds....
Compound(s) tested through a broad panel of 38 ligand binding and enzyme assays targeting the Central Nervous System. Used to determine selectivity and potential GI liabilities of compounds....
... The ProteoSpin Detergent Clean-up Micro Kit provides ... removal of SDS, Triton X-100 and other detergents ... spin-column chromatography using Norgens patented protein resin as ... processing 2 50 g of either acidic or ...
Biology Products: