Navigation Links
Researchers insert identification codes into mouse embryos
Date:11/18/2010

Researchers from the Department of Cell Biology, Physiology and Immunology at Universitat Autnoma de Barcelona (UAB), in collaboration with researchers from the Institute of Microelectronics of Barcelona (IMB-CNM) of the Spanish National Research Council (CSIC), have developed an identification system for oocytes and embryos in which each can be individually tagged using silicon barcodes. Researchers are now working to perfect the system and soon will test it with human oocytes and embryos.

The research, published online in Human Reproduction, represents a first step towards designing a direct labelling system of oocytes and embryos. The objective was to develop a system which minimises risks when identifying female gametes and embryos during in vitro fertilisation and embryo transfer procedures, to reduce the phases of the clinical process requiring control and supervision by two embryologists.

Microscopic silicon codes, fabricated using microelectronic techniques, were employed in the research. In previous tests, researchers verified the innocuousness of silicon particles in human cells, particularly in macrophages. In the present study, the codes were microinjected into the perivitelline space of mouse embryos, located between the cell membrane and the zona pellucida, a cover which surrounds the plasma membrane of the embryo. Since the embryo exits the zona pellucida before its implantation in the uterus, this approximation should allow the embryo to free itself of the identification codes when leaving the zona pellucida.

This research shows that labelled embryos develop normally in culture up to the blastocyst stage, the phase of development which precedes implantation. Researchers also studied the retention of the codes throughout the culture process, the easiness in reading the codes in a standard microscope, and their elimination when embryos free themselves from the zona pellucida. The research also verified the effi
'/>"/>

Contact: Maria Jesus Delgado
MariaJesus.Delgado@uab.cat
34-935-814-049
Universitat Autonoma de Barcelona
Source:Eurekalert

Page: 1 2

Related biology news :

1. Researchers learn that genetics determine winter vitamin D status
2. Researchers link an African lizard fossil in Africa with the Komodo dragon in Indonesia
3. FSU researchers helping K-12 teachers bring science down to Earth
4. As Arctic temperatures rise, tundra fires increase, researchers find
5. Researchers discover potential genetic target for heart disease
6. Researchers link cerebral malaria to epilepsy, behavior disorders
7. Researchers grow Rett syndrome in a Petri dish
8. U of A researchers can predict heart transplant patients health earlier
9. UCLA researchers discover a potential target for therapy for patients with a deadly prostate cancer
10. Jefferson researchers receive W.W. Smith Charitable Trust
11. Studying the metabolome of smokers, Lombardi researchers find early signs of damage
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/20/2015)... Calif. , Aug. 20, 2015 ... on consumers that are active and healthy. However, ... in the hospital environment to help improve diagnostic ... a video from the Wearable Technologies Conference ... discussed new applications for wearables in healthcare.    ...
(Date:8/20/2015)... 2015 NXT-ID, Inc. (NASDAQ: NXTD ) ... on the growing mobile commerce market and creator of ... Smart Card Alliance and the EMV Migration Forum.  ... Smart Card Alliance Latin America (SCALA) Chapter provides NXT-ID, ... thought leaders promoting adoption of smart card technology. ...
(Date:8/18/2015)... PRINCETON, N.J. , Aug. 18, 2015 ... be a key contributor to the Submission ... hosted by IRISS, a non-profit forum. Dedicated to ... IRISS provides a neutral platform for industry, ... to share information and work towards a ...
Breaking Biology News(10 mins):Leaf Healthcare Releases Video from Wearable Technology Conference on New Applications for Wearables in the Hospital Environment 2Leaf Healthcare Releases Video from Wearable Technology Conference on New Applications for Wearables in the Hospital Environment 3NXT-ID, Inc. Joins Smart Card Alliance and EMV Migration Forum 2NXT-ID, Inc. Joins Smart Card Alliance and EMV Migration Forum 3NXT-ID, Inc. Joins Smart Card Alliance and EMV Migration Forum 4Navitas, a Key Contributor in IRISS Forum Webinar 2Navitas, a Key Contributor in IRISS Forum Webinar 3
... four of the world,s largest wind farms showed an increase ... connected to local meteorological effects of the turbines. The ... at a rate of .72 degrees Celsius per decade during ... an effect most likely caused by the turbulence in turbine ...
... team of chemical engineers led by Paul J. Dauenhauer ... new, high-yield method of producing the key ingredient used ... inexpensive and currently creates the chemical p-xylene with an ... feedstock, Dauenhauer says. The research is published in the ...
... knowing how the chemistry inside the cell changes as ... example, controls everything from cell proliferation to differentiation to ... in cells from bacteria to humans. It,s a chemical ... in hopes of treating or eliminating a wide range ...
Cached Biology News:NASA satellite measurements imply Texas wind farm impact on surface temperature 2Chemical engineers at UMass Amherst find high-yield method of making xylene from biomass 2Chemical engineers at UMass Amherst find high-yield method of making xylene from biomass 3Molecular spectroscopy tracks living mammalian cells in real time as they differentiate 2Molecular spectroscopy tracks living mammalian cells in real time as they differentiate 3Molecular spectroscopy tracks living mammalian cells in real time as they differentiate 4Molecular spectroscopy tracks living mammalian cells in real time as they differentiate 5
(Date:9/2/2015)... ... September 02, 2015 , ... Genedata, a leading provider of ... Genedata Screener ® version 13.0 at ELRIG Drug Discovery 2015. This latest version ... set of new capabilities. Screener now supports High Throughput Flow Cytometry (HT-Flow) and ...
(Date:9/1/2015)... , Sept. 1, 2015 Prostate ... death in American men. One in seven ... 233,000 new cases are diagnosed annually. That said, ... using a powerful new technique, MRI Fusion Biopsy, ... large cancer lesions, treating only the affected areas ...
(Date:9/1/2015)... MILWAUKEE , Sept. 1, 2015 ... Eric Floyd , Ph.D., MBA as Chief ... (DLSS).  In this newly created role, Dr. Floyd ... well as a portfolio of pre-commercial and post ... medical affairs and medical communications.  Dr. Floyd brings ...
(Date:9/1/2015)... , ... September 01, 2015 , ... ... diseases has been discovered by researchers at the Keck Graduate Institute and its ... untreatable diseases. , The findings were published online on August 27 by Scientific ...
Breaking Biology Technology:New Genedata Screener 13.0 with Support for High Throughput Flow Cytometry and DMPK Unveiled at ELRIG 2New Genedata Screener 13.0 with Support for High Throughput Flow Cytometry and DMPK Unveiled at ELRIG 3New Genedata Screener 13.0 with Support for High Throughput Flow Cytometry and DMPK Unveiled at ELRIG 4September Is Prostate Cancer Awareness Month 2September Is Prostate Cancer Awareness Month 3September Is Prostate Cancer Awareness Month 4Dohmen Life Science Services Appoints Eric Floyd, Ph.D. as Chief Science Officer 2Dohmen Life Science Services Appoints Eric Floyd, Ph.D. as Chief Science Officer 3Scientists Discover New Use for an Old Therapy Inhibiting Deadly Pathogens Including Ebola and Anthrax 2Scientists Discover New Use for an Old Therapy Inhibiting Deadly Pathogens Including Ebola and Anthrax 3Scientists Discover New Use for an Old Therapy Inhibiting Deadly Pathogens Including Ebola and Anthrax 4
... Scientific Group,Inc. (OTC Bulletin Board: BMSN) announced today that ... its management team. Feng Lin, M.D., Ph.D. has,joined the ... Panahi is serving as Quality Assurance Director. , ... bring tremendous expertise to the,administrative operations of BMSN,s laboratories ...
... VIA Pharmaceuticals, Inc. (Nasdaq: VIAP ), a ... the treatment of cardiovascular and metabolic disease, today announced ... "Phenylalkyl N-Hydroxyureas for Combating Atherosclerotic Plaque", covering the use ... atherosclerosis. This patent is also pending in other ...
... WaferGen Biosystems, Inc. (OTC Bulletin Board: WGBS), a ... biology and stem cell research systems, today announced ... System. These validation results were presented today ... University of Pittsburgh School of Medicine ...
Cached Biology Technology:Bio-Matrix Scientific Group Announces New Hires to Management Team 2VIA Pharmaceuticals Announces Grant of New Patent on Lead Compound VIA-2291 2VIA Pharmaceuticals Announces Grant of New Patent on Lead Compound VIA-2291 3VIA Pharmaceuticals Announces Grant of New Patent on Lead Compound VIA-2291 4Data on WaferGen's SmartChip(TM) System Presented at 16th International Molecular Medicine Tri-Conference 2Data on WaferGen's SmartChip(TM) System Presented at 16th International Molecular Medicine Tri-Conference 3Data on WaferGen's SmartChip(TM) System Presented at 16th International Molecular Medicine Tri-Conference 4Data on WaferGen's SmartChip(TM) System Presented at 16th International Molecular Medicine Tri-Conference 5
HNF-1 Purified Anti-Mouse, Anti-Rat, Anti-Rabbit, Anti-Human clone 2, Isotype Mouse IgG 1 , 50 µg Consult technical datasheet for details....
... Immunogen KLH-conjugated, synthetic peptide ... (RRGPHRNPG-PGDDDGQRSRSSS) of mouse p19ARF. ... amino acids 62-75. Clone 5-C3-1. ... evaluated by immunoblot. ...
EDG-1 Western blot control Source: Cell Lysate Application: Western Blotting Control...
Complete cell culture media with cytokines...
Biology Products: