Navigation Links
Researchers identify specific lung cancer susceptibility gene
Date:4/15/2009

CINCINNATIUniversity of Cincinnati (UC) cancer cell biologists have identified a distinct gene linked to increased lung cancer susceptibility and development. They say this geneknown as RGS17could result in a genetic predisposition to develop lung cancer for people with a strong family history of the disease.

With further investigation, they believe the gene could be used to identify high-risk patients who may benefit from earlier, more aggressive lung cancer screening.

Marshall Anderson, PhD, and his colleagues report their findings in the April 15, 2009, issue of the journal Clinical Cancer Research.

"Understanding how the RGS17 gene impacts cancer development could change clinical diagnosis and treatment as radically as discovery of the breast cancer genes (BRCA1 and BRCA2) did," explains Anderson, who has led the multi-institutional Genetic Epidemiology of Lung Cancer Consortium (GELCC) studying the genetic basis of lung cancer since 1997. "A proven genetic test could help us identify people at risk before the disease progresses."

According to the American Cancer Society, lung cancer is the leading cause of cancer related disease and death. Although tobacco smoke is the primary environmental cause of the disease, science has shown there is also a strong genetic component to the disease.

"This study represents a significant contribution to our understanding of lung cancer susceptibility and is another step toward to the goal of preventive medicine," says David Christiani, MD, MPH, a professor of occupational medicine and environmental health at the Harvard School of Public Health, whose two-page commentary on the study is published in conjunction with the GELCC team's scientific findings. "The authors undertook a daunting challenge of performing a family-based study of lung cancer in an effort to identify specific causal genes."

Genes, which are located in fixed positions on the cell's chrom
'/>"/>

Contact: Amanda Harper
amanda.harper@uc.edu
513-558-4657
University of Cincinnati
Source:Eurekalert

Page: 1 2

Related biology news :

1. CSHL researchers explain process by which cells hide potentially dangerous DNA segments
2. Stem cell therapy makes cloudy corneas clear, according to Pitt researchers
3. Biomedical researchers invited to design experiments for the International Space Station
4. Caltech researchers train computers to analyze fruit-fly behavior
5. International climate change researchers meet, review latest findings
6. Einstein researchers devise a fast and sensitive way to detect ricin
7. NC State researchers find soy may aid in treating canine cancers
8. Queens researchers shine light on compact fluorescent bulb problems
9. Penn researchers demonstrate a new model for drug discovery with a fluorescent anesthetic
10. Researchers discover primer to plant defense system
11. MDC researchers prevent virus induced myocarditis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/22/2014)... , Dec. 22, 2014  The 2014 Holiday ... biometrics industry as Acuity Market Intelligence reports that ... finally be open. Acuity forecasts that intensifying demand ... that incorporate biometrics will drive a global market ... biometric devices by 2020.   According ...
(Date:12/19/2014)... Dec. 18, 2014 Research and Markets ... of the "iPhone 5S Fingerprint Sensor - ... report to their offering. ... of AuthenTec in July 2012, Apple introduced the ... is currently the only device of Apple incorporating ...
(Date:12/19/2014)... 2014 Research and Markets ( http://www.researchandmarkets.com/research/86ncd6/micro_market ... Market Monitor: North America Perimeter Security Systems Market" ... http://photos.prnewswire.com/prnh/20130307/600769 The North American perimeter security ... 3.6% from 2014 to 2019. Although the U.S. market ... Canada is expected to grow at a ...
Breaking Biology News(10 mins):First Season of Holiday Shopping with Mobile Biometric Payments Wraps Up With a Present for Biometrics Industry: A Rosy Forecast for More Than 2 Billion Users of 4.8 Billion Mobile Biometric Devices by 2020 2iPhone 5S Fingerprint Sensor - Apple/AuthenTec TMDR92 & Sapphire - Technology Report 2Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 2Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 3
... STATION N.J., PRINCETON, N.J. and JAMAICA PLAIN, Mass., ... (through an affiliate), Medarex, Inc. (NASDAQ: MEDX) and ... Massachusetts Medical School (UMMS) today announced that they ... CDA-1 and CDB-1 (also known as MDX-066/MDX-1388 and ...
... Cambridge, UK Wolf-Hirschhorn Syndrome (WHS) is a human ... with WHS have a characteristic set of facial features, ... forehead, and highly arched eyebrows. Other symptoms associated ... and skeletal abnormalities, and the severity of these symptoms ...
... AWRE ) today announced that it has amended and ... of comments and a request from the Securities and Exchange ... range of the tender offer to between $2.20 and $2.60 ... share. Aware has also extended the expiration date for the ...
Cached Biology News:Mass Biologic Labs/UMass Med School and Medarex license C. difficile monoclonal antibody to Merck 2Mass Biologic Labs/UMass Med School and Medarex license C. difficile monoclonal antibody to Merck 3Mouse model provides a new tool for investigators of human developmental disorder 2Aware, Inc. Amends and Extends Dutch Auction Tender Offer 2Aware, Inc. Amends and Extends Dutch Auction Tender Offer 3Aware, Inc. Amends and Extends Dutch Auction Tender Offer 4
(Date:12/19/2014)... CA (PRWEB) December 18, 2014 With ... limited time special on Sartorius Biohit products . ... on mLINE pipettes, Picus Electronic Pipette Trade-in Program, and ... Health and Safety officers around the world. They are ... pipetting. Other features include:, ,     Full volume ...
(Date:12/17/2014)... December 16, 2014 The Activated ... 2013, which is why IBISWorld updated its original industry ... to benefit from an intensified focus on environmental policy. ... new emission standards for power plants and a range ... to IBISWorld Industry Analyst Sarah Kahn, “a range of ...
(Date:12/17/2014)... 2014 Once more, EMAAR has ... packaged waste water treatment plant to phase one of ... (KAEC). Two years ago Bioshaft successfully supplied and operated ... two residential towers with an occupancy of 900 residences. ... million gallons per day and was signed on September ...
(Date:12/17/2014)... Texas , Dec. 16, 2014  Vermillion, Inc. ... focused on gynecologic disease, today announced the next step ... a premier bio-analytics solutions provider with the naming of ... President and Chief Executive Officer, while current Chairman of ... continue to serve as Chairman. These changes are effective ...
Breaking Biology Technology:Major Pipette Distributor Pipette.com Announces Sartorius Year End Specials 2Activated Carbon Manufacturing in the US Industry Market Research Report Has Been Updated from IBISWorld 2Activated Carbon Manufacturing in the US Industry Market Research Report Has Been Updated from IBISWorld 3Vermillion Names Valerie Palmieri CEO; James LaFrance to continue as Chairman of Board 2Vermillion Names Valerie Palmieri CEO; James LaFrance to continue as Chairman of Board 3Vermillion Names Valerie Palmieri CEO; James LaFrance to continue as Chairman of Board 4
... firm Bruker AXS announced on Tuesday it will ... materials research and analysis software. The deal is expected to ... transaction, which was finalized on Aug. 13 according to Bruker's ... Commission, states that Bruker will acquire all shares of SOCABIM's ...
... Wisconsin companies were among CIO Magazine's 2005 ... theme, the Bold 100, was awarded to companies the ... the company despite great risks. , ,Winners were selected ... detailing their practices in business and IT, review by ...
... the U.S. food supply from terrorism and natural disasters has ... its original November dates. , ,The Great Lakes Agro-Security ... Milwaukee, with as many as 1,000 people expected from the ... with the Wisconsin Procurement Institute, is helping to plan the ...
Cached Biology Technology:Bruker acquires French X-ray software company 2CUNA and Lands' End win IT applications award 2
SP6 RNA Polymerase, 50 l, 20 U/l ,Cap Scribe Buffer, 100 l, 5x conc....
... catalyzes the transfer of the ... 5-terminus of polynucleotides or to ... The enzyme, purified from recombinant ... to phosphorylate RNA, DNA and ...
... Labsystems Nepheloskan Ascent is the ... measurement in microplates. Nepheloskan measures ... ultra-sensitive technique for particle quantification. ... solubility testing in drug discovery, ...
Anti-VDAC (Voltage-Dependent Anion Channel) AVOID FREEZE/THAW CYCLES. Recognizes the porin 31HL protein. Corresponds to mAb 1 in the literature....
Biology Products: