Navigation Links
Researchers identify genetic markers to predict male fertility
Date:5/23/2012

The diagnosis of male fertility is usually performed through the observation of the sperm in the microscope. However, a normal quality semen does not guarantee an adequate fertility. In fact, there is a considerable proportion of cases of unexplained infertility and data suggest that abnormal sperm function may have a genetic or molecular origin.

A study performed by scientists at the Bellvitge Biomedical Research Institute (IDIBELL) and the Puigvert Foundation has identified a gene expression fingerprint associated with very low pregnancy rates in semen donors with normal seminal quality. The detected genetic fingerprint is a sensitive marker of low sperm fertilizing capacity. The results of the study have been advanced in the online edition of the journal Human Reproduction and the technology developed has been protected by a European patent application. The study also won the second prize for the best paper at the 29th Congress of the Spanish Fertility Society (SEF) held last week in Granada (Spain).

The study compares the diagnostic efficiency of fertility measured from the pattern of expression of RNA (ribonucleic acid) of sperm assessment parameters that are performed on samples from donors of semen used in intrauterine insemination. The researchers analyzed samples from 68 single, young and healthy donors which fertility wasn't known previously.

Significant differences

The researchers analyzed the expression profile of 85 genes in the sperm of donors with different rates of pregnancy resulting from intrauterine inseminations. The selection of these 85 genes was performed from RNA footprint normal fertile men already established in previous research. From this analysis, there were found significant differences in the expression of individual genes among the eight samples with worse and better pregnancy rates. On this basis, researchers found that combining the results of the expression of four of these gen
'/>"/>

Contact: Jordi Morat
comunicacio@idibell.cat
IDIBELL-Bellvitge Biomedical Research Institute
Source:Eurekalert

Page: 1 2

Related biology news :

1. NC State researchers get to root of parasite genome
2. Researchers find animal with ability to survive climate change
3. Researchers find an essential gene for forming ears of corn
4. Researchers note differences between people and animals on calorie restriction
5. Researchers study acoustic communication in deep-sea fish
6. Researchers discover that growing up too fast may mean dying young in honey bees
7. Researchers study how pistachios may improve heart health
8. UI researchers find potentially toxic substance present in Chicago air
9. Researchers develop new self-training gene prediction program for fungi
10. Case Western Reserve University researchers track Chernobyl fallout
11. Childrens National researchers develop novel anti-tumor vaccine
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/27/2014)... a group of fish began exploring land and evolved into ... how these ancient fish used their fishy bodies and fins ... play remain scientific mysteries. , Researchers at McGill University ... living fish, called Polypterus , to help show what ... of the water. Polypterus is an African fish ...
(Date:8/27/2014)... An invasive grass species frequently found in forests has ... feed on American toads, a new University of Georgia ... introduced to the U.S. in the early 1900s, is ... spread to more than a dozen states in the ... roads and in forests, it can survive in widely ...
(Date:8/27/2014)... /PRNewswire-iReach/ -- The IEEE Engineering in Medicine and Biology ... International Conference (EMBC,14), this year being held at the ... Illinois , from Tuesday, August 26 through Saturday, ... industry professionals in science, medicine, and engineering are registered ... This year,s conference theme is ...
Breaking Biology News(10 mins):Walking fish reveal how our ancestors evolved onto land 2More wolf spiders feasting on American toads due to invasive grass, UGA study shows 2More wolf spiders feasting on American toads due to invasive grass, UGA study shows 3Global Leaders In Science, Medicine, And Engineering Gather For The 36th Annual International Conference Of The IEEE Engineering In Medicine And Biology Society, August 26-30 In Chicago 2Global Leaders In Science, Medicine, And Engineering Gather For The 36th Annual International Conference Of The IEEE Engineering In Medicine And Biology Society, August 26-30 In Chicago 3
... a wide range of highly ordered structures that feature ... innovation inspired by nature humans hope to emulate ... A key to accomplishing this is understanding how protein-folding ... of a protein is extended from individual proteins ...
... October 31, 2012 Scientists at The Scripps ... of an important set of enzymes. The new inhibitors, ... used to study the functions of enzymes known as ... regulate. Early tests in mouse macrophages suggest that DAGL-inhibiting ...
... research discovery has the potential to revolutionize the biological ... found that when a single protein involved in brain ... the brain functioning of mice that cause symptoms that ... in children. Because this protein has similar functions in ...
Cached Biology News:Folding funnels key to biomimicry 2Folding funnels key to biomimicry 3New inhibitors of elusive enzymes promise to be valuable scientific tools 2New inhibitors of elusive enzymes promise to be valuable scientific tools 3Single protein targeted as the root biological cause of several childhood psychiatric disorders 2
(Date:8/27/2014)... August 27, 2014 After the boom ... that the next beverage craze is going to be ... that formulators can use Stress Relief energy pattern which ... the making of a beverage, including minerals, herbs and ... energy, channeling that power into rapid recovery and helping ...
(Date:8/27/2014)... August 27, 2014 WriteResult, LLC – ... has once again shown superiority when it comes to ... completing the ePRO portion of their most recent study ... Japan-based pharma chose WriteResult’s digital writing platform to collect ... the first to complete drew data from a number ...
(Date:8/26/2014)...  NeuroSigma, Inc., a Los Angeles ... today announced that it has filed a registration statement ... Commission relating to a proposed initial public offering of ... offered and the price range for the proposed offering ... will act as the book-running manager for the proposed ...
(Date:8/26/2014)... August 26, 2014 The 20 ambassadors ... ALS (YFALS) community issued the following statement on Facebook ... awareness and driving new funding specifically for ALS research: ... water and some ice would raise all this awareness ... our families, and on behalf of the entire ALS ...
Breaking Biology Technology:Stress Relief: 1 Way to De-Stress Your Beverage Formula 2Stress Relief: 1 Way to De-Stress Your Beverage Formula 3Stress Relief: 1 Way to De-Stress Your Beverage Formula 4A Perfect Record: WriteResult Maintains a 100% On-Time ePRO Record with Latest Irritable Bowel (IBS) Study Data Lock 2ALS TDI’s Young Faces of ALS Ambassadors Thank You for Accepting the Ice Bucket Challenge to End ALS 2ALS TDI’s Young Faces of ALS Ambassadors Thank You for Accepting the Ice Bucket Challenge to End ALS 3ALS TDI’s Young Faces of ALS Ambassadors Thank You for Accepting the Ice Bucket Challenge to End ALS 4
... Peterson, president and CEO of ZyStor Therapeutics, Inc. ... for attendees of this year's Midwestern bioscience forum. , ... Wisconsin biotechnology companies with another presenter, Dr. Irene Hrusovsky, ... of molecular diagnostic products. , ,Like many of the ...
... engine optimization (SEO) tactics have one thing in common: ... and incorporating them into a web site, marketers can ... a desirable search engine ranking requires good information about ... website's industry or topic. A good place to start ...
... - CDW Corp. , a $6 billion-a-year information technology ... agreed to acquire the stock of Madison-based Berbee Information ... ,The acquisition, which has been approved by the boards of ... October, subject to regulatory approvals and approval by Berbee shareholders. ...
Cached Biology Technology:ZyStor to exhibit cell disorder treatments 2Search engine optimization: What's the word? 2Search engine optimization: What's the word? 3Berbee believes acquisition by CDW will make it a national IT player 2Berbee believes acquisition by CDW will make it a national IT player 3
MAb to Catenin beta, N-terminal (exon 2) Catenin, beta, N-terminal (exon 2)...
... Phosphatase 2 (LPP2) fractionated ... solution Solution in ... 0.08% sodium azide. unique ... human LPP2 protein. The ...
Rabbit polyclonal to Retinoic Acid Receptor beta 2 ( Abpromise for all tested applications). entrezGeneID: 5915...
Ca2+ Channel Ca gamma 2 Purified Anti-Mouse, Anti-Rat, Anti-Human clone Polyclonal, Isotype Rabbit Ig, 50 µl Consult technical datasheet for details....
Biology Products: