Researchers identify cancer preventive properties in common vitamin ... (resveratrol suppressed the expression of...)

Researchers identify cancer preventive properties in common vitamin supplement

Date:7/6/2008

resveratrol suppressed the expression of CYP1B1 and the formation of 2,3,7,8-Tetrachlorodibenzo-p-dioxin, two known risk factors for breast cancer.

Rogan said resveratrol works by inducing an enzyme called quinone reductase, which reduces the estrogen metabolite back to inactive form. By making estrogen inactive, resveratrol decreases the associated risk.

The current study was conducted in laboratory cultures, and will need to be confirmed in larger human trials, Rogan said.

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Contact: Jeremy Moore
Jeremy.moore@aacr.org
267-646-0557
American Association for Cancer Research
Source:Eurekalert

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