Navigation Links
Researchers identify a cell type that limits stroke damage
Date:1/27/2009

Quebec City, January 27, 2009A research team including Serge Rivest of University Laval's Faculty of Medicine has demonstrated the existence of a type of cells that limits brain damage after a stroke. The study was recently published in the online version of Nature Medicine.

Laboratory experiments showed that three days after a stroke, the affected area of the brain is 20% larger in mice without regulatory T (Treg) cells than in normal mice. Effects on locomotor control are also more severe in mice lacking this type of cells.

"These results lead us to believe that we could better preserve crucial functions like sight, speech, or control of the limbs if we rapidly stimulated the production of Treg cells in stroke victims," commented Professor Rivest. "We are particularly enthusiastic about this discovery because we already know what chemicals stimulate the production of Treg cells," continued the researcher. "So a treatment may be available in the not too distant future. We also believe that the protective effect of Treg cells could be used to treat other types of brain damage, especially that caused by head injury."

Part of the brain damage occurring after a stroke is caused by the body's immune response. Cells such as microglia and lymphocytes provoke harmful effects similar to those observed during nervous system infections. When performing their cleaning functions, these cells also attack healthy cells, enlarging the damaged area of the brain and threatening certain brain functions. Researchers had suspected the existence of a mechanism that slows this harmful effect of immune cells in the brain, but no one had yet been able to demonstrate it.

Treg cells, produced in the bone marrow and other organs of the immune system, migrate to the brain during the first few days after a stroke. They limit the extent of secondary damage by blocking the production of neurotoxins and modulating the action of lymphocytes and mi
'/>"/>

Contact: Jean-Franois Hupp
jean-francois.huppe@dc.ulaval.ca
418-656-7785
Universit Laval
Source:Eurekalert

Page: 1 2

Related biology news :

1. Researchers identify proteins involved in new neurodegenerative syndrome
2. Texas researchers and educators head for Antarctica
3. MGH researchers describe new way to identify, evolve novel enzymes
4. University of Pennsylvania researchers develop formula to gauge risk of disease clusters
5. U of MN researchers discover noninvasive diagnostic tool for brain diseases
6. U of Minnesota researchers discover noninvasive diagnostic tool for brain diseases
7. Researchers discover new strategies for antibiotic resistance
8. Researchers find new taste in fruit flies: carbonated water
9. Binghamton University researchers investigate evolving malaria resistance
10. UIC researchers find promising new targets for antibiotics
11. Researchers develop simple method to create natural drug products
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2014)... alert the world to Global Warming, has called for ... underground. He says that Carbon Capture, combined with limits ... avoid global warming getting out of control over the ... made the call during his presentation to the International ... meeting to discuss Carbon Capture and Storage. , ...
(Date:8/27/2014)... The mechanical force that a single fungal cell or ... small, but it plays a heavy role in setting up ... fact, it may not be too much of a stretch ... without the ability to respond to the touch of beneficial ... a professor of agronomy at the University of Wisconsin-Madison. ...
(Date:8/27/2014)... Reportlinker.com announces that a new market ... Law Enforcement Biometrics Market in North America ... About Biometrics Biometrics is a technology that ... their physical or behavioral patterns. It involves the ... as fingerprints, face recognition, DNA, palm print, hand ...
Breaking Biology News(10 mins):Global warming pioneer calls for CO2 to be taken from atmosphere and stored underground 2A touching story: The ancient conversation between plants, fungi and bacteria 2A touching story: The ancient conversation between plants, fungi and bacteria 3Law Enforcement Biometrics Market in North America 2014-2018 2Law Enforcement Biometrics Market in North America 2014-2018 3Law Enforcement Biometrics Market in North America 2014-2018 4Law Enforcement Biometrics Market in North America 2014-2018 5
... alAbsi, Ph.D., and a team of national collaborators have ... National Institutes of Health (NIH) for their research, AutoSense: ... alAbsi is a professor and founding director of Duluth ... SchoolDuluth Campus. , The project is among the first ...
... UC Davis Institute of Transportation Studies (ITS-Davis) will,co-sponsor ... Research to Practice" next month in Berkeley. ... local government,officials, private industry leaders, consultants and advisers, ... include: Innovative highway and ...
... million gift to the University of Michigan Health System is ... a mission of supporting fundamental research to advance the understanding ... of human diseases. The A. Alfred Taubman Medical Research ... for the retail pioneer whose funding and vision led to ...
Cached Biology News:Mustafa al'Absi Ph.D. and national team awarded major NIH grant 2$22 million gift from Alfred Taubman launches new biomedical research institute 2$22 million gift from Alfred Taubman launches new biomedical research institute 3$22 million gift from Alfred Taubman launches new biomedical research institute 4
(Date:8/28/2014)... PrimeSource Building Products, Inc., a ... SoundConnect to support their communication needs with ... web conferencing platform GlobalMeet powered by SoundConnect. The ... SoundConnect delivers award winning “results driven” business ... will be utilizing GlobalMeet powered by SoundConnect ...
(Date:8/27/2014)... Green & Grow Inc. (GGI) has raised ... secured Otter Capital as a significant new partner. Otter ... GGI’s Agriplier™ technology, building on recent compelling field trial ... first meeting, we have been impressed with Otter Capital’s ... Alan Sobba, President and CEO of GGI. “We look ...
(Date:8/27/2014)... 27, 2014   MSC , a healthcare performance ... announced the appointment of Mary Beth Loesch ... years of experience preparing companies for rapid growth and ... Vice President of Corporate Development and Healthcare. In that ... , as well as corporate strategy and marketing. Previously, ...
(Date:8/27/2014)... 27, 2014 Research and Markets ... Lactic Acid  (Biodegradable Polymer, Food & Beverage, Personal ... to 2019" report to their offering. ... with an asymmetrical carbon atom. The main applications ... food and beverage, personal care product, and pharmaceutical ...
Breaking Biology Technology:PrimeSource Chooses SoundConnect as Collaboration Provider 2Green & Grow Inc. Secures $6M Series B Funding from Otter Capital 2Green & Grow Inc. Secures $6M Series B Funding from Otter Capital 3MSC names Mary Beth Loesch President and CEO 2Global Lactic Acid (Biodegradable Polymer, Food & Beverage, Personal Care & Pharmaceutical) Market - Trends & Forecasts to 2019 2
... 7 Interleukin Genetics,Inc. (Amex: ILI ), a ... genetic tests for sale to the,emerging personalized health market, ... 2007. The Company recorded revenue of $2.6 million ... for third quarter ended September 30,2006, a 92% increase. ...
... Symbol: MS, EDMONTON, Nov. 7 /PRNewswire-FirstCall/ - ... the treatment of multiple sclerosis (MS), today,announced that ... the,Company,s phase II MINDSET-01 trial of MBP8298 in ... and recommended that,the trial continue as per the ...
... Transgenomic Inc. (OTC,Bulletin Board: TBIO) announces the following Webcast: What: ... Conference Call, When: ... http://www.transgenomic.com/events.asp?id=6 , How: Live ... address above., ...
Cached Biology Technology:Interleukin Genetics, Inc. Reports Third Quarter 2007 Financial Results 2Interleukin Genetics, Inc. Reports Third Quarter 2007 Financial Results 3Interleukin Genetics, Inc. Reports Third Quarter 2007 Financial Results 4Interleukin Genetics, Inc. Reports Third Quarter 2007 Financial Results 5Interleukin Genetics, Inc. Reports Third Quarter 2007 Financial Results 6BioMS Medical's relapsing-remitting multiple sclerosis trial receives positive review from Data Safety Monitoring Board 2Webcast Alert: Transgenomic Inc. Announces Third Quarter 2007 Earnings Release Conference Call Webcast 2
...
Whole blood is collected from healthy guinea pigs of either sex from US source which are free of visible diseases at time of blood collection. Hemolytic titer: CH50 = 435 units...
... vitro cell labeling mix, 92.5 ... solution stabilized with 0.1% 2-mercaptoethanol ... 3,4-dicarboxylic acid. *Amino acid mixture ... containing l-[35S]Methionine and l-[35S]Cysteine. * ...
...
Biology Products: