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Researchers get a first look at the mechanics of membrane proteins
Date:4/17/2011

Sciences, Schulten, Gumbart and graduate student Christophe Chipot found that proteins get inserted into the membrane in two stages. First, the ribosome "pushes" the growing protein into the membrane channel, and then, in a second step, the protein enters the membrane.

The original push, driven by the chemical energy that the ribosome harvests from other high-energy molecules in the cell, allows even highly charged proteins to pass easily into the oily, nonpolar environment of the membrane, the researchers found.


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Contact: Diana Yates
diya@illinois.edu
217-244-1073
University of Illinois at Urbana-Champaign
Source:Eurekalert  

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