Navigation Links
Researchers generate first complete 3-D structures of bacterial chromosome
Date:10/21/2011

ome inside of the cell." said Esteban Toro, PhD, one of the study authors and now a post doctoral fellow at the University of Pennsylvania. "These results suggest that the parS site in Caulobacter crescentus determines the orientation and global structure of the entire chromosome and are the only sequence elements that stably anchor the chromosome to the cell."

The ability for scientists to perform structure function studies on chromosomes has the potential to yield powerful new insights into the biology of genomes. "When we began this project, most scientists were assessing the positions of a handful of genomic loci and attempting to derive general conclusions about genome structure. We were unhappy with this approach and sought to develop an integrated experimental approach to generate higher-resolution, and genome-wide insights," Umbarger said.

"This isn't something we could have predicted from just looking at the DNA sequence," said Dekker. "This study illustrates how an investigation of 3D genomic structure can provide insights into how the complex relationships between genome sequence and structure can impact function. By studying genomic architecture we can potentially identify new classes of genomic sequences that are important in chromosome function and structure that we otherwise couldn't."


'/>"/>

Contact: Jim Fessenden
james.fessenden@umassmed.edu
508-856-2000
University of Massachusetts Medical School
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. NC State researchers get to root of parasite genome
2. Researchers find animal with ability to survive climate change
3. Researchers find an essential gene for forming ears of corn
4. Researchers note differences between people and animals on calorie restriction
5. Researchers study acoustic communication in deep-sea fish
6. Researchers discover that growing up too fast may mean dying young in honey bees
7. Researchers study how pistachios may improve heart health
8. UI researchers find potentially toxic substance present in Chicago air
9. Researchers develop new self-training gene prediction program for fungi
10. Case Western Reserve University researchers track Chernobyl fallout
11. Childrens National researchers develop novel anti-tumor vaccine
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/20/2014)... 2014) Women who are poor experience higher cortisol ... elevated levels of the stress hormone, putting them ... according to a new research from the University of ... the American Journal of Human Biology , is ... it directly to the socioeconomic status of their mothers ...
(Date:8/20/2014)... to about 4,000 members, it triggers an important first ... special type of comb used for rearing male reproductive, ... of Neurobiology and Behaviour at Cornell University, led by ... honeybee colonies. The results are published in Springer,s journal ... , Reproduction isn,t always a honeybee colony,s top priority. ...
(Date:8/20/2014)... and its energy is finally utilized for the ... mostly build from silicon based semiconductors, also harness ... the development of cheaper and renewable photovoltaics consists ... protein complexes of photosynthesis. Prof. Dr. Matthias Rgner,s ... cyanobacteria that live in a hot spring in ...
Breaking Biology News(10 mins):CU Denver researcher shows economic disparities impact infant health 2Worker bees 'know' when to invest in their reproductive future 2A semi-artificial leaf faster than 'natural' photosynthesis 2
... helping scientists better understand the threatened loggerhead turtle, which is ... published today in the journal PLOS ONE describes ... technique that links chemical signatures of the turtles, diets and ... technique just as effective as expensive satellite tracking. Little ...
... (Sept. 20, 2012) The latest conference to ... focuses on the molecular mechanisms involved in exercise-mediated ... neurological, and dynamic molecular and cellular pathways. Entitled ... be held October 10-13, 2012 in Westminster, Colorado. ...
... the same DNA, but each cell,s identity is defined by ... any given moment in time. In animals, this cellular memory ... no memory and, as such, has the potential to become ... cellular memory passes from generation to generation, with potentially harmful ...
Cached Biology News:New turtle tracking technique may aid efforts to save loggerhead 2American Physiological Society's latest conference focuses on integrative biology of exercise 2American Physiological Society's latest conference focuses on integrative biology of exercise 3Pollen cells keep memory to control jumping genes 2Pollen cells keep memory to control jumping genes 3
(Date:8/20/2014)... Livermore, California (PRWEB) August 20, 2014 ... to develop and apply the most complete climate ... challenging and demanding climate change issues. , Eight ... combining forces with the National Center for Atmospheric ... in the new effort. Other participating national laboratories ...
(Date:8/20/2014)... Not long ago, it was more or ... late in the development cycle – even after the ... suggest that, like many things GxP, expectations for early ... multiple drug sponsors have been required by authorities to ... phase I/II. It’s not only clinical trial material containers ...
(Date:8/20/2014)... (PRWEB) August 20, 2014 ... released today including improvements to the enterprise replication ... connectors for Lucene, SOLR and Elasticsearch. This release ... this high performance triplestore – GraphDB™ was formerly ... in deploying the only mature enterprise resilient RDF ...
(Date:8/19/2014)... , Aug. 19, 2014 A Geisinger researcher ... nominated for a Centers for Disease Control and Prevention ... major public health concern. Joseph Boscarino ... one of a team of researchers nominated for the ... Shepard Science Award for Data Methods and Study Design. ...
Breaking Biology Technology:New Project Is the ACME of Addressing Climate Change 2New Project Is the ACME of Addressing Climate Change 3Are Extractable and Leachables going Phase-Appropriate? New Webinar Hosted by Xtalks 2Ontotext Improves Its RDF Triplestore, GraphDB™ 6.0: Enterprise Resilience, Faster Loading Speeds and Connectors to Full-Text Search Engines Top the List of Enhancements 2Ontotext Improves Its RDF Triplestore, GraphDB™ 6.0: Enterprise Resilience, Faster Loading Speeds and Connectors to Full-Text Search Engines Top the List of Enhancements 3Ontotext Improves Its RDF Triplestore, GraphDB™ 6.0: Enterprise Resilience, Faster Loading Speeds and Connectors to Full-Text Search Engines Top the List of Enhancements 4Geisinger investigator nominated for federal award 2Geisinger investigator nominated for federal award 3
... in Training and Preparing for the NFL, Combine Use SURGEX(TM) ... ... Clubs(TM), BASKING RIDGE, N.J., ... (OTC Bulletin Board: MBTG), announced today that SURGEX(TM) is,currently being administered ...
... ... * Clears Process For Phase I Clinical Later In Year ... Influenza Antigen Used Was Non-Egg-Based ... 15 Carrington,Laboratories, Inc. (OTC Bulletin Board: CARN) today announced that its,wholly owned ...
... 07/06 ... % ... 27.97 74.7 14 Other EU Countries (2) 9.66 22.4 8.22 22.0 ... 3.3 10, SLIT 34.55 ...
Cached Biology Technology:Pro Football Prospects Training at TEST Sports Clubs(TM) Use SURGEX(TM) as Part of Their Pre-Combine Training Regime 2Pro Football Prospects Training at TEST Sports Clubs(TM) Use SURGEX(TM) as Part of Their Pre-Combine Training Regime 3Pro Football Prospects Training at TEST Sports Clubs(TM) Use SURGEX(TM) as Part of Their Pre-Combine Training Regime 4GelVac(TM) Nasal Powder H5N1 (Bird Flu) Influenza Vaccine Passes Preclinical Toxicology Studies 2GelVac(TM) Nasal Powder H5N1 (Bird Flu) Influenza Vaccine Passes Preclinical Toxicology Studies 3GelVac(TM) Nasal Powder H5N1 (Bird Flu) Influenza Vaccine Passes Preclinical Toxicology Studies 4STALLERGENES: 2007: A Further Year of Strong Growth: Up 16% 2
... Ultrapure ACS Reagent Grade C 19 ... Formula Weight: 691.95 PRODUCT SPECIFICATIONS Form: Powder ... Interval: pH 3.0 - Yellow ... a tracking dye in agarose and acrylamide ...
... reads and processes raw microarray ... data for analysis. ,Package ... 1-year license for Feature Extraction ... CD-ROM containing Feature Extraction software ...
... Feature Extraction Software reads and ... to prepare microarray data for ... one 1-year license for ... accounts , * one ...
... 4 H 10 O 2 S ... SPECIFICATIONS Form: White crystalline powder Assay: ... Identity: By IR Melting Point: greater ... DTT: less than or equal to ...
Biology Products: