Navigation Links
Researchers gain genome-wide insights into patterns of the world's human population structures
Date:5/14/2009

buted to differences among individuals, and 5 to 15 percent is due to differences between populations.

In contrast to these broad-scale patterns, more recently researchers have tried to look at fine-scale population structure. Usually these studies focus on only the two or three top- ranking axes of genetic variation emerging from the statistical analysis. For example, studies of European individuals have shown a strong correlation between the top two axes of genetic variation and the actual geographical location of the sampling.

In their newly published findings, UW researchers demonstrated that substantial information on population structure is hidden more deeply in the genomic data. They were able to identify 18 significant, informative axes of variation. Some of these distinguished particular populations.

The UW researchers also conservatively estimated the set of all of the SNPs, or specific, tiny DNA code differences, matching each of the most informative axes of variation. These variations represent numerous fixed positions on the human genome where different biomarkers can sit and thereby form a "genomic signature" of population structure. They also allow for more detailed inferences, the UW researchers noted, about the evolutionary forces that shape the fine-scaled patterns of human population structure.

"The genome-wide distribution of these markers," Akey believes, "can largely be accounted for by genetic drift." Genetic drift is gradual accumulation of random changes in the gene pool of small populations. Akey added that some of these variations, however, do cluster in regions of the human genome considered to be targets of recent adaptive evolution.

The researchers also observed patterns of human genetic variation that correlated with geography in essentially every continental group. While such geographical patterns have been described in European samples, the researchers think that the extent to which such
'/>"/>

Contact: Leila Gray
leilag@u.washington.edu
206-685-0381
University of Washington
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. UMMS researchers isolate first neuroprotective gene in patients with amyotrophic lateral sclerosis
2. NOAA researchers: Blue whales re-establishing former migration patterns
3. OHSU researchers study the idling brain
4. Hebrew University researchers neutralize tumor growth in embryonic stem cell therapy
5. Researchers find snippet of RNA that helps make individuals remarkably alike
6. Stowers researchers develop whole genome sequencing approach for mutation discovery
7. Pfizer supports open access publishing for researchers in low-income countries
8. Genetic secrets of date palm unlocked by researchers at Weill Cornell Medical College in Qatar
9. Researchers identify a molecule that increases the risk of cardiac insufficiency
10. Researchers discover that gene switches on during development of epilepsy
11. Researchers report moderately large potential for red tide outbreak in Gulf of Maine region
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/13/2015)... April 13, 2015 According ... "Global Biometrics Market Forecast & Opportunities, 2020", the global ... of around 14% till 2020. The biometrics market ... scale implementation and review of biometric management systems. ... new products with greater efficiency, are resulting in ...
(Date:4/9/2015)... SAN JOSE, Calif. , April 9, 2015 /PRNewswire/ ... of human interface solutions, announced today that it will ... 2015 on Thursday, April 23, 2015, after the close ... call for analysts and investors at 2:00 p.m. PT ... information.    To participate on the live ...
(Date:4/2/2015)... 2, 2015 In the ... far outperforms the strongest competitors, showing outstanding performance ... the system is capable of a throughput of ... up to be ten times faster than most ... performance.      (Photo: http://photos.prnewswire.com/prnh/20150402/738673-a ...
Breaking Biology News(10 mins):Global Biometrics Market to Cross US$ 21 Billion by 2020: TechSci Research 2Synaptics to Report Third Quarter Results on April 23 2DERMALOG AFIS Emerges as Performance Winner in NIST Benchmark Test 2DERMALOG AFIS Emerges as Performance Winner in NIST Benchmark Test 3
... June 15 Robert H. Wurtz, PhD, a pioneer and ... the 2010 Neuroscience Prize of The Peter and Patricia Gruber ... and controls eye movements laid the groundwork for subsequent research ... scientists to a deeper understanding of how the brain is ...
... new study shows that humans and tiny aquatic animals known ... to sex. Barely visible without a microscope, rotifers eat ... But the females of certain rotifer species can do something ... themselves, or they can initiate a process that allows sexual ...
... part of the 20th century have prevented massive amounts ... equivalent of 590 billion metric tons of carbon dioxide ... Stanford Earth scientists. The yield improvements reduced the ... typically involves burning of trees and other plants, which ...
Cached Biology News:Neuroscientist Robert H. Wurtz receives the $500,000 Gruber neuroscience prize 2Neuroscientist Robert H. Wurtz receives the $500,000 Gruber neuroscience prize 3New study documents use of hormone progesterone in simple microscopic aquatic animals 2New study documents use of hormone progesterone in simple microscopic aquatic animals 3New study documents use of hormone progesterone in simple microscopic aquatic animals 4High-yield agriculture slows pace of global warming, say Stanford researchers 2High-yield agriculture slows pace of global warming, say Stanford researchers 3High-yield agriculture slows pace of global warming, say Stanford researchers 4
(Date:5/1/2015)... DALLAS , May 1, 2015 ... report "Antibody Production Market by Product (Equipment, Consumables), by ... (Biopharmaceutical Companies, Diagnostic Labs, Research Institutes) - Analysis ... the report studies the global Antibody Production Market ... This market is expected to reach $2.572 Billion ...
(Date:4/30/2015)... April 30, 2015   Tamir Biotechnology , a ... update on its Ebola antiviral therapy program. ... TMR004, is currently being evaluated and considered by a ... against Ebola. During the first quarter of 2015, the ... To Accelerate The Evaluation of Potential Treatments and Vaccines ...
(Date:4/30/2015)... 2015 Oxford Finance LLC ("Oxford"), a specialty ... and healthcare services companies, today announced the closing of ... Celula, Inc., a diagnostic testing company focused on improving ... care and improved outcomes.  Proceeds of the loan will ... commercialization of its products in the U.S. and ...
(Date:4/30/2015)... , April 30, 2015  Pfenex Inc. ... in the development of biosimilar therapeutics including high ... the closing of its previously announced underwritten public ... at a public offering price of $15.50 per ... the underwriters of their option to purchase up ...
Breaking Biology Technology:Antibody Production Market worth $2.572 Billion by 2019 2Antibody Production Market worth $2.572 Billion by 2019 3Antibody Production Market worth $2.572 Billion by 2019 4Tamir Biotechnology Provides Update on TMR004 Development Against Mutating Ebola 2Tamir Biotechnology Provides Update on TMR004 Development Against Mutating Ebola 3Tamir Biotechnology Provides Update on TMR004 Development Against Mutating Ebola 4Oxford Finance Provides $10 Million Debt Financing to Celula 2Pfenex Inc. Announces Closing of Public Offering of Common Stock and Full Exercise of Underwriters' Option to Purchase Additional Shares 2
... spent time with a leading producer of fashion goods interviewing ... find out what aspects of the shopping experience really matter ... a difference to how much the customer buys and how ... ,Customers were invited to the companys facilities for one-on-one discussions ...
... Promega Corporation and Chemicon ... in which Chemicon may use and apply Madison-based ... ,Under the agreement, Chemicon, California-based division of Serologicals ... technology to develop and sell ddRNAi-based products and ...
... on the effects of outsourcing technology and offshore manufacturing ... Whatever the product, there is an effort to ship ... this are hurting many aspects of Americans industrial and ... whether you manufacture low- to high-tech products, maintain technology ...
Cached Biology Technology:Really Listening to Customers...AND Employees 2Really Listening to Customers...AND Employees 3Offshore outsourcing affects American workers 2Offshore outsourcing affects American workers 3
... marking pen has been designed to provide a thin ... specimen on a slide. This barrier creates the ... the target area on the slide. PAP Pen ... and acetone. It can be removed, if desired, ...
Mouse monoclonal antibody to QDPR - quinoid dihydropteridine reductase...
...
Anti-Conjugated Quinaldic Acid...
Biology Products: