Navigation Links
Researchers gain genome-wide insights into patterns of the world's human population structures
Date:5/14/2009

Through sophisticated statistical analyses and advanced computer simulations, researchers are learning more about the genomic patterns of human population structure around the world.

Revealing such patterns provides insights into the history of human evolution, the predominant evolutionary forces that shaped local populations, and the relationships among populations.

"Studying genomic patterns of human population structure also has practical applications in disease-gene mapping," noted Dr. Joshua M. Akey, University of Washington (UW) assistant professor of genome sciences. Akey is senior author of new genomic research findings about the fine-scale structure of diverse human populations. The results will be published May 15 in the American Journal of Human Genetics. The lead authors were Shameek Biswas and Dr. Laura B. Scheinfeldt, both of the UW Department of Genome Sciences.

A statistical method called principle component analysis allows researchers to look through a thick, voluminous fog of genetic data and see significant variations. The UW researchers applied this method to a data set of almost 650,000 SNPs (pronounced "snips").

A single nucleotide polymorphism is a genetic variation in which the DNA code differs by only one "letter" in the same DNA sequence from two individuals of the same species. The data set of 650,000 SNPs came from 944 unrelated persons representing 52 broadly classified populations living in several regions on seven continental groups: Africa, America, Central and South East Asia, East Asia, Europe, Middle East, and Oceania. This global sampling came from The Human Genome Diversity Project - Center for the Study of Human Polymorphisms

Most previous genomic studies of this nature have focused on broad-scale patterns of structure among geographically diverse populations, the UW researchers noted. These studies concluded that 85 to 95 percent of human genetic variation can be attri
'/>"/>

Contact: Leila Gray
leilag@u.washington.edu
206-685-0381
University of Washington
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. UMMS researchers isolate first neuroprotective gene in patients with amyotrophic lateral sclerosis
2. NOAA researchers: Blue whales re-establishing former migration patterns
3. OHSU researchers study the idling brain
4. Hebrew University researchers neutralize tumor growth in embryonic stem cell therapy
5. Researchers find snippet of RNA that helps make individuals remarkably alike
6. Stowers researchers develop whole genome sequencing approach for mutation discovery
7. Pfizer supports open access publishing for researchers in low-income countries
8. Genetic secrets of date palm unlocked by researchers at Weill Cornell Medical College in Qatar
9. Researchers identify a molecule that increases the risk of cardiac insufficiency
10. Researchers discover that gene switches on during development of epilepsy
11. Researchers report moderately large potential for red tide outbreak in Gulf of Maine region
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/9/2015)... JOSE, Calif. , July 9, 2015 ... the leading developer of human interface solutions, ... technology, the industry,s first fully hardware encapsulated ... Match-in-Sensor secure authentication technology is literally off ... storage and biometric matching within the fingerprint ...
(Date:7/8/2015)... DIEGO , July 8, 2015  Trovagene, ... cell-free molecular diagnostics, today announced the launch of ... the Company,s Precision Cancer Monitoring℠ (PCM) technology for ... receiving one or a combination of the novel ... Opdivo® (nivolumab), a PD-1 inhibitor. The 50-patient study ...
(Date:7/7/2015)... Calif. , July 7, 2015  Based ... market, Frost & Sullivan recognizes Credence ID, LLC ... Entrepreneurial Company of the Year Award. Credence ... to aid in its mission of offering enrollment ... populations globally. As Credence ID was formed by ...
Breaking Biology News(10 mins):Synaptics Announces World's First Match-in-Sensor Fingerprint Authentication Technology 2Synaptics Announces World's First Match-in-Sensor Fingerprint Authentication Technology 3Trovagene Initiates Study to Monitor Response to Immunotherapy in Melanoma Patients Using its Precision Cancer Monitoring Platform 2Trovagene Initiates Study to Monitor Response to Immunotherapy in Melanoma Patients Using its Precision Cancer Monitoring Platform 3Trovagene Initiates Study to Monitor Response to Immunotherapy in Melanoma Patients Using its Precision Cancer Monitoring Platform 4Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 2Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 3Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 4Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 5
... Scientists have discovered that autoimmunity can be triggered in the ... cells fail to recognize just one of the body's thousands ... view that autoimmunity can start in this cradle of the ... diseases emerge, such as the pancreas in the case of ...
... rising over the last two decades, and new research from ... increase is driven largely by the detection of small, presumably ... been paralleled by greater use of surgery for kidney cancer, ... "With increased early detection and treatment of small tumors, we ...
... without predators - at least this was the case up ... with cats and dogs on some islands of the Archipelago. ... in order to discover if such generally tame animals are ... novel predation threats. Scientists from the Max Planck Institute for ...
Cached Biology News:Autoimmune disease triggered if T cells miss a single protein early on 2Autoimmune disease triggered if T cells miss a single protein early on 3More kidney cancer is detected and treated early, yet death rate rises 2More kidney cancer is detected and treated early, yet death rate rises 3Too mellow for our predatory world 2Too mellow for our predatory world 3Too mellow for our predatory world 4
(Date:7/30/2015)... (PRWEB) , ... July 31, 2015 , ... Ralco is ... Center at the Lyon County Fair to be held August 5-9 in Marshall. The ... where their meals come from and how agriculture impacts their daily lives. This unique ...
(Date:7/30/2015)... and Dallas, TX, USA (PRWEB) , ... July ... ... innovative nano and microsystems, has appointed Francois Vieillard as Sales & Marketing Director. ... at executive positions, Francois Vieillard will be responsible for reinforcing Tronics’ business development ...
(Date:7/30/2015)... Diego , CA (PRWEB) , ... July 30, ... ... announced the successful completion of a field clinical study of its canine osteoarthritis ... developed together with Aratana Therapeutics (Kansas City, KS) and will be marketed in ...
(Date:7/30/2015)... , July 30, 2015  With over 60,000 customers across the globe, ISN improves ... 450 hiring organizations with more than 60,000 safe and reliable contractors in over 80 countries. ... ... Over ... Headquartered in Dallas, TX ...
Breaking Biology Technology:Ralco Announces Primary Sponsorship of Ralco Enrichment Center at Lyon County Fair 2Tronics appoints Francois Vieillard as Sales and Marketing Director 2VetStem Biopharma Successfully Completes Large Milestone Efficacy Study for its Flagship Canine Osteoarthritis Stem Cell Product 2VetStem Biopharma Successfully Completes Large Milestone Efficacy Study for its Flagship Canine Osteoarthritis Stem Cell Product 3ISN Reaches Over 60,000 Worldwide Customers 2ISN Reaches Over 60,000 Worldwide Customers 3
... 3 /PRNewswire-FirstCall/ - AEterna Zentaris Inc. (NASDAQ: ... company focused on endocrine therapy and oncology, today announced ... its partner and licensee for perifosine in the North ... Food and Drug Administration (FDA) regarding a Special Protocol ...
... - OncoGenex Pharmaceuticals (NASDAQ: OGXI ) announced today ... Thursday, August 6, 2009. OncoGenex will host a conference call ... discuss quarterly results. , The webcast can be accessed on ... www.oncogenex.com . Alternatively, you may access the live conference ...
... The years of ... big breakthrough in the search for a viable alternative feedstock for biodiesel in combination with ... happy to announce the much awaited commercial release of Couple oil crop cultivation (COC) technology. ... (PRWEB) August 3, 2009 ...
Cached Biology Technology:AEterna Zentaris Partner, Keryx, Announces Agreement with FDA on a Special Protocol Assessment for Phase 3 Trial with Perifosine (KRX-0401) for the Treatment of Multiple Myeloma 2AEterna Zentaris Partner, Keryx, Announces Agreement with FDA on a Special Protocol Assessment for Phase 3 Trial with Perifosine (KRX-0401) for the Treatment of Multiple Myeloma 3AEterna Zentaris Partner, Keryx, Announces Agreement with FDA on a Special Protocol Assessment for Phase 3 Trial with Perifosine (KRX-0401) for the Treatment of Multiple Myeloma 4Jatropha Couple Oil Crop Cultivation Technology Commercially Released 2Jatropha Couple Oil Crop Cultivation Technology Commercially Released 3
nucleophosmin (nucleolar phosphoprotein B23, numatrin), mRNA...
...
Acrylamide PAGE 40% Solution, 1 l. Category: Electrophoresis Systems & Standards & Reagents, Electrophoresis Standards and Reagents, Gel Casting Chemicals....
... MBP Coated Microplate, 96 Well ... #20 Magnesium/ATP Cocktail, #20-11 Blocking Buffer, ... Chemiluminescen LumiGLO™ Chemiluminescen Applications: ... Assurance: Routinely evalauted by ...
Biology Products: