Navigation Links
Researchers gain genome-wide insights into patterns of the world's human population structures
Date:5/14/2009

Through sophisticated statistical analyses and advanced computer simulations, researchers are learning more about the genomic patterns of human population structure around the world.

Revealing such patterns provides insights into the history of human evolution, the predominant evolutionary forces that shaped local populations, and the relationships among populations.

"Studying genomic patterns of human population structure also has practical applications in disease-gene mapping," noted Dr. Joshua M. Akey, University of Washington (UW) assistant professor of genome sciences. Akey is senior author of new genomic research findings about the fine-scale structure of diverse human populations. The results will be published May 15 in the American Journal of Human Genetics. The lead authors were Shameek Biswas and Dr. Laura B. Scheinfeldt, both of the UW Department of Genome Sciences.

A statistical method called principle component analysis allows researchers to look through a thick, voluminous fog of genetic data and see significant variations. The UW researchers applied this method to a data set of almost 650,000 SNPs (pronounced "snips").

A single nucleotide polymorphism is a genetic variation in which the DNA code differs by only one "letter" in the same DNA sequence from two individuals of the same species. The data set of 650,000 SNPs came from 944 unrelated persons representing 52 broadly classified populations living in several regions on seven continental groups: Africa, America, Central and South East Asia, East Asia, Europe, Middle East, and Oceania. This global sampling came from The Human Genome Diversity Project - Center for the Study of Human Polymorphisms

Most previous genomic studies of this nature have focused on broad-scale patterns of structure among geographically diverse populations, the UW researchers noted. These studies concluded that 85 to 95 percent of human genetic variation can be attri
'/>"/>

Contact: Leila Gray
leilag@u.washington.edu
206-685-0381
University of Washington
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. UMMS researchers isolate first neuroprotective gene in patients with amyotrophic lateral sclerosis
2. NOAA researchers: Blue whales re-establishing former migration patterns
3. OHSU researchers study the idling brain
4. Hebrew University researchers neutralize tumor growth in embryonic stem cell therapy
5. Researchers find snippet of RNA that helps make individuals remarkably alike
6. Stowers researchers develop whole genome sequencing approach for mutation discovery
7. Pfizer supports open access publishing for researchers in low-income countries
8. Genetic secrets of date palm unlocked by researchers at Weill Cornell Medical College in Qatar
9. Researchers identify a molecule that increases the risk of cardiac insufficiency
10. Researchers discover that gene switches on during development of epilepsy
11. Researchers report moderately large potential for red tide outbreak in Gulf of Maine region
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/10/2014)... RALEIGH, N.C. , Dec. 9, 2014  Valencell, ... announced it is seeing a staggering demand from its ... demand, the Company revealed, is not solely coming from ... industries as well. "A wearable is only ... a result, accuracy is the ultimate driver in long-term ...
(Date:12/10/2014)... December 9, 2014   ... Platform   Jifflenow, ... scheduling solutions for business-to-business (B2B) events, today announced ... in mobile near-field communication (NFC), Bluetooth low energy ... (Logo: http://photos.prnewswire.com/prnh/20140612/691055) , Jifflenow will integrate ...
(Date:12/3/2014)... IRVINE, Calif. , Dec. 2, 2014 /PRNewswire/ ... of globally deployed, innovative test solutions for military, ... the newest version of its successful TS-900 ... the performance and features of high-end systems to ... with outstanding value compared to traditional ATE. ...
Breaking Biology News(10 mins):Wearable Technology Products Demand Highly Accurate Biometric Technology 2Jifflenow And ITN International Bring Cutting-Edge Badge Scanning Technology To B2B Events 2Jifflenow And ITN International Bring Cutting-Edge Badge Scanning Technology To B2B Events 3Marvin Test Solutions Brings New Capabilities to PXI-Based Semiconductor Test with TS-960 2Marvin Test Solutions Brings New Capabilities to PXI-Based Semiconductor Test with TS-960 3
... jaw of a 120 million year old marine reptile suggest that ... The healed bite wounds were probably made by a member of ... behaviour of extinct sea creatures from the time of dinosaurs. The ... Polonica . Found in the remote desert near the town ...
... when cosmetics, shampoos, skin creams, and other personal care ... to plant-derived extracts and other natural ingredients government ... the silicone-based ingredients long used in these products. That,s ... of Chemical & Engineering News (C&EN), ACS, weekly newsmagazine. ...
... providing the inspiration for University of Adelaide computer science ... increase wind farm productivity. Senior Lecturer Dr Frank ... a "selection of the fittest" step-by-step approach called "evolutionary ... account wake effects, the minimum amount of land needed, ...
Cached Biology News:Battle scars found on an ancient sea monster 2Evolutionary lessons for wind farm efficiency 2
(Date:12/19/2014)... 18, 2014 Today, TiFiber, ... pilot production facility and future company headquarters in ... innovative new materials that safely and effectively control ... because of its historic, strong support for manufacturing, ... attract leading edge, technology-based companies such as TiFiber. ...
(Date:12/19/2014)... contrast to traditional LED lights where the spectrum is ... LED technology to incorporate their spectra in a single ... in low proximity installations. The Valoya L-series offers high ... is up to four times longer than commonly used ... clearly higher when compared to traditional fluorescent or LED ...
(Date:12/19/2014)...   ISN has released its third annual ... publication series. With data aggregated from over eight ... within its online contractor management platform, ISNetworld, this three-part ... (KPI) statistics. The Contractor ... is available in two industry specific volumes: Oil ...
(Date:12/17/2014)... Houston, TX (PRWEB) December 17, 2014 ... marketing and administration for Stoller Group. In this position, ... Stoller Group, on administrative matters, develop marketing strategy and ... and services. , “Achim has tremendous knowledge and ... president of Stoller Group. “His experience and innovative thinking ...
Breaking Biology Technology:Technology Company TiFiber™ to Establish Production Facility in Fort Smith, Arkansas with Support from Local Investors 2Technology Company TiFiber™ to Establish Production Facility in Fort Smith, Arkansas with Support from Local Investors 3Technology Company TiFiber™ to Establish Production Facility in Fort Smith, Arkansas with Support from Local Investors 4ISN Releases Third Edition of US Contractor Health & Safety Performance Indicators Publication Series 2ISN Releases Third Edition of US Contractor Health & Safety Performance Indicators Publication Series 3Achim Noack Joins Stoller Group as Global Vice President of Marketing and Administration 2
... Switzerland, December 19 An exclusive license,for the ... for,lung infections in Cystic Fibrosis patients was signed ... Japan transferred relevant,rights to Axentis Pharma AG of ... to the licensed technology and a phase II ...
... . , By means of X-ray interferometers, lengths ... resolution of less than one nm. The low translation velocity ... difficult, could now be increased by a factor of 100 ... , X-ray interferometers can measure lengths in the mm range ...
... DuPont today congratulated,growers planting Pioneer(R) brand sorghum hybrids ... in the 2007 National Sorghum Producers, (NSP),Yield and ... Pioneer sorghum,hybrid 84G62., Farmers growing Pioneer sorghum ... segments. First-, second- and third-place national,honors were awarded ...
Cached Biology Technology:Cystic Fibrosis: License Agreement Boosts Development of Therapy Against Lung Infections 2Cystic Fibrosis: License Agreement Boosts Development of Therapy Against Lung Infections 3Faster X-ray interferometers due to single-photon interference 2DuPont Congratulates Growers Planting Pioneer(R) Brand Sorghum Hybrids in Winning Majority of National Categories in Yield Contest 2
...
MOUSE ANTI S. NEWPORT SALMONELLA HADAR...
MAb to Hu-IFN-Gamma RC2 (CD118), NON-Neutralizing, Clone MMHGR-2 Binds to but does not neutralize human interferon gamma receptor...
Secure-Seal™ hybridization chamber gasket, eight chambers, 9 mm diameter, 0.8 mm deep *set of 20*...
Biology Products: