Navigation Links
Researchers gain genome-wide insights into patterns of the world's human population structures
Date:5/14/2009

Through sophisticated statistical analyses and advanced computer simulations, researchers are learning more about the genomic patterns of human population structure around the world.

Revealing such patterns provides insights into the history of human evolution, the predominant evolutionary forces that shaped local populations, and the relationships among populations.

"Studying genomic patterns of human population structure also has practical applications in disease-gene mapping," noted Dr. Joshua M. Akey, University of Washington (UW) assistant professor of genome sciences. Akey is senior author of new genomic research findings about the fine-scale structure of diverse human populations. The results will be published May 15 in the American Journal of Human Genetics. The lead authors were Shameek Biswas and Dr. Laura B. Scheinfeldt, both of the UW Department of Genome Sciences.

A statistical method called principle component analysis allows researchers to look through a thick, voluminous fog of genetic data and see significant variations. The UW researchers applied this method to a data set of almost 650,000 SNPs (pronounced "snips").

A single nucleotide polymorphism is a genetic variation in which the DNA code differs by only one "letter" in the same DNA sequence from two individuals of the same species. The data set of 650,000 SNPs came from 944 unrelated persons representing 52 broadly classified populations living in several regions on seven continental groups: Africa, America, Central and South East Asia, East Asia, Europe, Middle East, and Oceania. This global sampling came from The Human Genome Diversity Project - Center for the Study of Human Polymorphisms

Most previous genomic studies of this nature have focused on broad-scale patterns of structure among geographically diverse populations, the UW researchers noted. These studies concluded that 85 to 95 percent of human genetic variation can be attri
'/>"/>

Contact: Leila Gray
leilag@u.washington.edu
206-685-0381
University of Washington
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. UMMS researchers isolate first neuroprotective gene in patients with amyotrophic lateral sclerosis
2. NOAA researchers: Blue whales re-establishing former migration patterns
3. OHSU researchers study the idling brain
4. Hebrew University researchers neutralize tumor growth in embryonic stem cell therapy
5. Researchers find snippet of RNA that helps make individuals remarkably alike
6. Stowers researchers develop whole genome sequencing approach for mutation discovery
7. Pfizer supports open access publishing for researchers in low-income countries
8. Genetic secrets of date palm unlocked by researchers at Weill Cornell Medical College in Qatar
9. Researchers identify a molecule that increases the risk of cardiac insufficiency
10. Researchers discover that gene switches on during development of epilepsy
11. Researchers report moderately large potential for red tide outbreak in Gulf of Maine region
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/21/2014)... -- C-Labs LLC, a leading provider of remote and ... announced the appointment of John Traynor to ... advisor to the firm, Mr. Traynor will now oversee ... out of the C-Labs office in Redmond, ... , Chief Executive Officer. Photo - ...
(Date:11/18/2014)...  The Secure Identity & Biometrics Association (SIBA) ... the formation of The Airport Entry and Exit ... and Biometric Entry and Exit Solutions Framework for ... from BORDERPOL, the international non-profit organization that works ... regarding border security, traveler and migration systems. ...
(Date:11/18/2014)... The Parenteral Drug Association (PDA) today confirmed that seven officials ... least seven more will participate in the upcoming 2014 PDA ... Washington D.C. , Dec. 2-4. ... the regulatory agencies in the United States ... to help advance the use of metrics in the regulatory ...
Breaking Biology News(10 mins):C-Labs Names Former Microsoft and Bsquare Executive as Chief Operating Officer 2Identity Management, Document Authentication and Biometric Companies Form "The Airport Entry and Exit Working Group", Releasing the Framework to Help Guide the Department of Homeland Security and Congress Towards Solutions 2Identity Management, Document Authentication and Biometric Companies Form "The Airport Entry and Exit Working Group", Releasing the Framework to Help Guide the Department of Homeland Security and Congress Towards Solutions 3FDA's Janet Woodcock, EMA's Emer Cooke Headline PDA Quality Metrics Conference 2
... a tiny ball of ice, a minimally invasive interventional ... caused by nerve damage, according to data being presented ... Meeting in New Orleans. "Cryoneurolysis could have big ... neuralgia, which can be unbearable and is very difficult ...
... reopens completely blocked bowel arteries, preventing damage and ... severe pain and leads to excessive weight loss, ... Interventional Radiology,s 38th Annual Scientific Meeting in New ... saves lives," said Daniel A. Leung, M.D., program ...
... A genetic analysis of the avian flu virus responsible ... virus evolving to adapt to human cells, raising concern about ... The collaborative study, conducted by a group led by Masato ... Infectious Diseases, and Yoshihiro Kawaoka of the University of Wisconsin-Madison ...
Cached Biology News:Freezing nerves knocks pain out cold 2Stenting blocked bowel arteries saves lives 2New bird flu strain seen adapting to mammals, humans 2
(Date:11/22/2014)... 2014 During his lifetime Richard L. ... to surround himself with great people and take risks ... friends often marveled at his extraordinarily courageous attitude when ... and -- even with his death impending—that’s how he ... that would ultimately take his life. , Carrying on ...
(Date:11/22/2014)... 22, 2014 The “Chiral Chromatography ... by Material (Metal, Glass, Plastic), by Application [GC, ... - Forecast to 2018” analyses and studies the ... North America, Europe, Asia, and Rest of the ... 15 figures spread through 135 pages and in-depth ...
(Date:11/21/2014)... --  TRU-D SmartUVC LLC and its UK partners, Rapid ... robot, TRU-D SmartUVC, at FIS 2014 in Harrogate, ... at Stand 23. The conference, hosted by Federation ... largest infection-related event of its kind and brings together ... leading events of its type throughout the world. This annual ...
(Date:11/21/2014)... (PRWEB) November 20, 2014 ... (XNA, Chassis, Oligos, Enzymes, Cloning kits), Technology ... Application (Biofuels, Pharmaceuticals, Biomaterials, Bioremediation) - Global ... major market drivers, threats, opportunities, and challenges. ... 46 figures spread through 185 pages and ...
Breaking Biology Technology:Sherry Sharp, Wife of CarMax Founder, Richard Sharp, Accepts Seat on Board of Cure Alzheimer’s Fund 2Sherry Sharp, Wife of CarMax Founder, Richard Sharp, Accepts Seat on Board of Cure Alzheimer’s Fund 3Chiral Chromatography Columns Market worth $87.8 Million by 2018 - New Research Report by MarketsandMarkets 2Chiral Chromatography Columns Market worth $87.8 Million by 2018 - New Research Report by MarketsandMarkets 3Chiral Chromatography Columns Market worth $87.8 Million by 2018 - New Research Report by MarketsandMarkets 4Chiral Chromatography Columns Market worth $87.8 Million by 2018 - New Research Report by MarketsandMarkets 5TRU-D SmartUVC to Showcase Superbug-Killing Robot at FIS 2014 2TRU-D SmartUVC to Showcase Superbug-Killing Robot at FIS 2014 3Synthetic Biology Market Expected to Reach $5,630.4 Million in 2018 - New Report by MarketsandMarkets 2Synthetic Biology Market Expected to Reach $5,630.4 Million in 2018 - New Report by MarketsandMarkets 3Synthetic Biology Market Expected to Reach $5,630.4 Million in 2018 - New Report by MarketsandMarkets 4
... Pharmaceuticals, Inc.,(Nasdaq: AMLN ) will be presenting at ... 2008 at 10:00 a.m. PT in Las Vegas. Michael,York, ... providing a corporate overview., The live presentation and ... made available following the event. The webcast and,recording will ...
... Agreement expands Dermagraft presence within government channels, ... May 7 Advanced,BioHealing, Inc. (ABH) and ... on the promotion of Dermagraft(R) within the ... of the agreement,Regenesis will provide its specialized ...
... Demonstrate Abbott,s Most Advanced NNR Candidate ABT-089 ... Adults With ADHD, ABBOTT PARK, Ill., May ... leading scientists will present new Phase II data ... agonist, is a,potentially effective and safe treatment for ...
Cached Biology Technology:Advanced BioHealing and Regenesis Biomedical Form Co-Promotion Alliance for Dermagraft(R) 2Advanced BioHealing and Regenesis Biomedical Form Co-Promotion Alliance for Dermagraft(R) 3Abbott Scientists Present a New Approach for Treating Attention-Deficit Hyperactivity Disorder 2Abbott Scientists Present a New Approach for Treating Attention-Deficit Hyperactivity Disorder 3Abbott Scientists Present a New Approach for Treating Attention-Deficit Hyperactivity Disorder 4Abbott Scientists Present a New Approach for Treating Attention-Deficit Hyperactivity Disorder 5
... Round Well Plate Sterile ... wide range of 384-well ... high-throughput screening and research. ... assays and are suitable ...
Request Info...
Aldolase A (N-15)...
Bovine Aortic Smooth Muscle Cells (BAOSMC) (>500,000 cells)...
Biology Products: