Navigation Links
Researchers find signal that switches on eye development -- could lead to 'eye in a dish'
Date:10/24/2007

s experiencing much higher levels of ADP. The Warwick team hypothesized that ATP must be released in a short burst from the location where the eye will develop so that it can be converted to ADP by E-NTPDase2, thereby providing the trigger for eye development. They were able to measure these short bursts of ATP using ATP sensors specially developed by Professor Dale. This is the first time researchers have been able to see and measure bursts of ATP so early in the development of living creatures.

The genes that initiate and direct eye development are well known and are collectively termed the Eye Field Transcription Factors (EFTFs). One of the mysteries of the field is how these genes get turned on in the correct location and at the correct time to initiate eye development. The Warwick research shows that this short burst of ATP followed by accumulation of ADP is a key signal for initiating expression of the EFTFs and hence the development of the eye.

The discovery of this surprising new signal that literally switches on eye development it is not restricted to frogs. Mutations to the E-NTPDase2 gene on the human 9th chromosome is already known to cause severe head and eye defects. This suggests that this newly discovered mechanism for triggering eye development applies across a wide range of species.

This new understanding of how eye development is triggered will greatly assist researchers exploring stem cells connected to eye development and opens up an avenue of a research that could in just a few decades lead to the ability to produce an eye in a dish.


'/>"/>

Contact: Peter Dunn
p.j.dunn@warwick.ac.uk
0247-652-3708
University of Warwick
Source:Eurekalert

Page: 1 2

Related biology news :

1. Researchers discover way to make cells in the eye sensitive to light
2. Researchers find how protein allows insects to detect and respond to pheromones
3. Researchers Uncover Key Step In Manufacture of Memory Protein
4. NYU researchers simulate molecular biological clock
5. Researchers reveal the infectious impact of salmon farms on wild salmon
6. Researchers identify target for cancer drugs
7. Vital step in cellular migration described by UCSD medical researchers
8. ASU researchers finds novel chemistry at work to provide parrots vibrant red colors
9. UCSD researchers maintain stem cells without contaminated animal feeder layers
10. Researchers discover molecule that causes secondary stroke
11. Researchers find missing genes of ancient organism
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/12/2015)... 12, 2015  Securus Technologies, a leading provider ... public safety, investigation, corrections and monitoring, announced the ... electronically capture, analyze and identify participants of a ... This system can: , ... and subsequent sign-on process is actually the person ...
(Date:6/10/2015)... June 10, 2015 According ... Market by Technology (Ultrasound, TOF, Structured Light, Stereo ... Entertainment, Automotive) and by Geography - Trends & ... the market is expected to reach $3,319.71 Million ... between 2015 and 2020. Browse 71 ...
(Date:6/9/2015)... 09, 2015 Research and Markets  ( ... "Gesture Recognition & Touchless Sensing Market by ... & Others), Product (Biometric & Sanitary Equipment) & ... report to their offering. The total ... to reach $ 23.55 Billion by 2020 at ...
Breaking Biology News(10 mins):Securus Announces Patent Issued for Authorized Presence Verification During Video Visitation 23D Sensor Market Worth $3,319.71 Million by 2020 23D Sensor Market Worth $3,319.71 Million by 2020 33D Sensor Market Worth $3,319.71 Million by 2020 4Global Gesture Recognition & Touchless Sensing (Technology, Application & Products) Market 2015-2020 2
... PASADENA, Calif.Our belief as to whether we will likely succeed ... or losingdirectly affects the levels of neural effort put forth ... new brain-imaging study by neuroscientists at the California Institute of ... Richard A. Andersen, the James G. Boswell Professor of Neuroscience ...
... ASHEVILLE, NC USDA Forest Service Southern Research ... foresters, landowners and others concerned about nonnative invasive plants ... "A Field Guide for the Identification of Invasive Plants ... of the very popular "Nonnative Invasive Plants of Southern ...
... A unique blob-like creature that lived in the ocean approximately ... model in research published today in the journal Biology ... primitive species on early Earth looked like and how they ... on Earth today. The scientists, from Imperial ...
Cached Biology News:Caltech: Gain and loss in optimistic versus pessimistic brains 2Caltech: Gain and loss in optimistic versus pessimistic brains 3Forest Service updates free guide to 'Invasive Plants in Southern Forests' 2Ancient blob-like creature of the deep revealed by scientists 2
(Date:6/30/2015)... , June 30, 2015  The University of ... Biosciences (CCE/Bio) and UC San Diego Extension announced ... be held Aug.  12 – 14, 2015, at ... three-day workshop provides an intense exposure to best ... and is well-suited to biologists, process engineers and ...
(Date:6/30/2015)... 2015 /PRNewswire/ - RepliCel Life Sciences Inc. (OTCQB: ... company focused on the development of autologous cell ... Phase 1/2 clinical trial of RCT-01, being tested ... has been enrolled and their tissue biopsy sent ... is comprised of non-bulbar dermal sheath (NBDS) cells ...
(Date:6/30/2015)... ... 2015 , ... Southern Illinois University Edwardsville Chancellor Julie Furst-Bowe ... of instruction at Chippewa Valley Technical College (CVTC) and will assume her new ... SIUE during the past three years,” Furst-Bowe said. “I want to thank SIUE’s ...
(Date:6/30/2015)... (PRWEB) , ... June 30, 2015 , ... ... digital media company, launched “Cannavoices,” an unprecedented digital video and broadcast initiative. ... but also the most dynamic collection of legal medical cannabis stories ever assembled. ...
Breaking Biology Technology:UC San Diego Extension to Offer Third Annual Microbial Fermentation Workshop 2RepliCel Life Sciences Enrolls First Participant in Phase 1/2 Clinical Trial of RCT-01 for Chronic Achilles Tendinosis 2RepliCel Life Sciences Enrolls First Participant in Phase 1/2 Clinical Trial of RCT-01 for Chronic Achilles Tendinosis 3RepliCel Life Sciences Enrolls First Participant in Phase 1/2 Clinical Trial of RCT-01 for Chronic Achilles Tendinosis 4SIUE’s Furst-Bowe Accepts VP of Instruction at CVTC 2SIUE’s Furst-Bowe Accepts VP of Instruction at CVTC 3Cannavoices Launches a Legal Medical Cannabis Documentary Initiative 2Cannavoices Launches a Legal Medical Cannabis Documentary Initiative 3
... , , , ... - OncoGenex Pharmaceuticals, Inc. ("OncoGenex" or the "Company") (NASDAQ: OGXI ) today reported unaudited financial results ... first quarter of 2010. , , , ... , Revenue for the first quarter ...
... May 6 /PRNewswire-Asia-FirstCall/ -- China Sky One Medical,Inc. ("China Sky One ... in the People,s Republic of China ,("PRC"), today announced that it will ... Tuesday, May 11, 2010 , to discuss its first,quarter of 2010 financial ... Joining ...
... BEIJING , May 6 /PRNewswire-Asia/ -- Sinovac Biotech Ltd. ... announced that it will release,its financial results for the first quarter ended ... 13, 2010 . The Company will host a,conference call on Thursday, May ... results and provide an update on recent corporate,developments. , ...
Cached Biology Technology:OncoGenex Reports First Quarter Financial Results 2OncoGenex Reports First Quarter Financial Results 3OncoGenex Reports First Quarter Financial Results 4OncoGenex Reports First Quarter Financial Results 5OncoGenex Reports First Quarter Financial Results 6OncoGenex Reports First Quarter Financial Results 7OncoGenex Reports First Quarter Financial Results 8OncoGenex Reports First Quarter Financial Results 9China Sky One Medical Announces Conference Call to Discuss First Quarter 2010 Results 2China Sky One Medical Announces Conference Call to Discuss First Quarter 2010 Results 3Sinovac to Host Conference Call to Report First Quarter 2010 Financial Results 2Sinovac to Host Conference Call to Report First Quarter 2010 Financial Results 3
Normal donkey serum collected from healthy normal donkeys....
This BioSolution package is excellent for doing fluorescence thermal melt experiments on nucleic acids, studies involving biomolecular interactions, protein folding experiments, and more!...
... Probes Fc OxyBURST Green reagent (F-2902) was ... Boston University to permit measurement of the ... the subsequent oxidative burst directly in the ... consists of bovine serum albumin (BSA) that ...
... of BAC (100+kb), fosmid (40kb), and large ... than any othe BAC vector. On command ... and easy recombinant DNA purification. Available with ... VC) vectors for the highest insert stability. ...
Biology Products: