Navigation Links
Researchers find gene critical to sense of smell in fruit fly
Date:1/19/2012

or of a predator.

Boekhoff-Falk and her group have studied distal-less (dll) for years, previously investigating its role in the fruit fly hearing system and its limb development.

The current studies of the olfactory system were done in larvae rather than the more typically studied adult flies. Dissecting the younger, smaller flies demands the steadiest of hands, but the payoff is that larvae offer a substantially simpler view of brain development and wiring as well as insights into events occurring extremely early in development.

The researchers found dll was required for the development and growth of multiple cell types in the olfactory system, including those that receive, relay and process olfactory information. Dll must work for normal olfactory behavior to occur in larvae. And when dll is defective, the sense of smell is not present.

Zeroing in on the MB, the UW researchers also discovered an essential relationship between dll and the longest-living and most prolific neural stem cells found in fruit flies.

Boekhoff-Falk's team found that in flies with a mutated version of dll, these neural stem cells failed to proliferate. No other scientists have observed such strong defects in these cells at such an early stage.

The scientists identified markers that will allow them to learn how the stem cells decide which specialized cells they will become and how their growth may be regulated.

"We want to identify the niche, or the stem cell microenvironment, and the cells there that supply growth inputs needed to keep the stem-ness of the cells," she says.

Boekhoff-Falk believes the parallels to human stem cell biology may be strong. "Our model may be useful for further analysis of how this gene regulates stem cells," she says.

The experiments also opened the door to a better understanding of the evolution of the sense of smell.

"The prevailing view is that fly and mammal olfact
'/>"/>

Contact: Dian Land
dj.land@hosp.wisc.edu
608-261-1034
University of Wisconsin-Madison
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. NC State researchers get to root of parasite genome
2. Researchers find animal with ability to survive climate change
3. Researchers find an essential gene for forming ears of corn
4. Researchers note differences between people and animals on calorie restriction
5. Researchers study acoustic communication in deep-sea fish
6. Researchers discover that growing up too fast may mean dying young in honey bees
7. Researchers study how pistachios may improve heart health
8. UI researchers find potentially toxic substance present in Chicago air
9. Researchers develop new self-training gene prediction program for fungi
10. Case Western Reserve University researchers track Chernobyl fallout
11. Childrens National researchers develop novel anti-tumor vaccine
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2014)... a novel method to help kidney stone sufferers ... treatment possible., Kidney stones represent a major medical ... left untreated, apart from being particularly painful, they ... In many patients treated successfully, stone recurrence is ... approach to diagnosis and treatment needs to be ...
(Date:4/17/2014)... the Cell Press journal Current Biology on ... novel sex lives. The Brazilian insects, which represent four ... , are the first example of an animal with ... identified in several different animals, Neotrogla is ... also reversed," says Kazunori Yoshizawa from Hokkaido University in ...
(Date:4/17/2014)... Branch at Galveston are the first to recommend ... cancer should begin colorectal cancer screening earlier than ... a high incidence of secondary colorectal cancers among ... recommendations that the younger women in this group ... their initial cervical cancer diagnosis instead of waiting ...
Breaking Biology News(10 mins):In sex-reversed cave insects, females have the penises 2Radiation therapy for cervical cancer increases risk for colorectal cancer 2
... University of Geneva have discovered a genetic mechanism that defines ... only a secondary role. The research published in Cell ... found in a DNA sequence that was thought, incorrectly, to ... when combined with one another, modulate the activity of the ...
... Urban legend warns shoveling snow causes heart attacks, and the ... with a family history of premature cardiovascular disease. However, until ... Two of the most important cardiology associations in the ... risk physical activity, but all the citation references indicate that ...
... end rot on tomatoes and cucumbers, bitter-pit in apples ... only compromises the flavor but also causes significant harvest ... be traced back to insufficient calcium uptake or faulty ... occur even if the soil provides sufficient calcium. A ...
Cached Biology News:Finger (mal)formation reveals surprise function of desert DNA 2
(Date:1/15/2014)... , Jan. 15, 2014 ­ RedBrick Health ... behavior change technology, today announces that EmblemHealth , ... and wellness company, is now providing the RedBrick Compass ... coaching program, to all of its members. EmblemHealth is ...
(Date:1/15/2014)... Reston, VA (PRWEB) January 15, 2014 ... education have continued their sponsorship of an annual competition ... interest in, and access to, innovative STEM study. The ... , TEAMS: Tests of Engineering Aptitude, Mathematics, and ...
(Date:1/15/2014)... 2014 Freeslate, Inc ., the ... that Lupin Limited, one of India’s top five pharmaceutical ... PharmD System for high throughput solid form screening. ... on a wide range of quality, affordable generic and ...
(Date:1/14/2014)... (PRWEB) January 14, 2014 Carahsoft and ... Thursday, January 23, 2014 at 2pm EST (11am PST), ... The topic focuses on how technology can turn raw, ... decisions for government agencies. The online webinar will last ...
Breaking Biology Technology:EmblemHealth Selects RedBrick Health to Power its Next-Generation Health Engagement and Behavior Change System 2EmblemHealth Selects RedBrick Health to Power its Next-Generation Health Engagement and Behavior Change System 3Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 2Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 3Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 4Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 5Lupin Selects Freeslate’s CM Protégé PharmD System to Accelerate Polymorph Screening for Drug Development 2Lupin Selects Freeslate’s CM Protégé PharmD System to Accelerate Polymorph Screening for Drug Development 3Webcast - Natural Language Processing: Converting Raw Data into Actionable Knowledge – Hosted by Carahsoft and CDS Federal Services 2
... of,the 2007 Nobel Prize in Physiology or Medicine ... Americans for Medical,Progress congratulates Mario R. Capecchi, Martin ... by the Karolinska Institute for their,animal-based research that ... treatments and cures for countless serious ailments., ...
... Company to Present Unique Business Model, SAN ... health,and wellness company and recent consecutive year award ... genetic research,announces today that it has been selected ... investor meeting, October 17, 2007 in San,Francisco, CA. ...
... 9 Boston Scientific,Corporation (NYSE: BSX ) ... cardioverter defibrillator (ICD). This approval,represents the first Boston ... death (SCD). The CONFIENT ICD, with an ... unnecessary right ventricular pacing. This product also,contains wireless ...
Cached Biology Technology:Nobel Award in Medicine Holds Strong Messsage for Animal Activists 2Salugen to Present at Nutrition Capital Network's First In-Person Investor Meeting 2Boston Scientific Announces European Approval of Next-Generation Implantable Defibrillator 2Boston Scientific Announces European Approval of Next-Generation Implantable Defibrillator 3
Monocarboxylate (lactate) transporter 2...
Chicken Anti-Human Stomatin-like 2 (STOML2 Polyclonal AntibodyNew Applications: ELISA, Western Blot...
MagSi monodispers, magnetic silica particles with modified surface for SO3 coupling chemistry....
Anti-Chicken IgY, (IgG) F(ab')2 Fragment Specific....
Biology Products: