Navigation Links
Researchers find critical regulator to tightly control deadly pulmonary fibrosis
Date:4/10/2012

of Biology.

The findings Li and his colleagues have presented have opened an exciting door to development of new therapeutics to fight the disease by aiming their sights on the CLYD gene.

"These results tell us that we now have a key regulator to target," said Binghe Wang, Director of the GSU Center for Diagnostics and Therapeutics and GRA Eminent Scholar in Drug Discovery and a co-author of the study.

"If we can target CLYD with a focus on regulating its protein level or activity, we may be able to better control fibrosis," said Wang, also chair of the Department of Chemistry at GSU. "There is a huge clinical potential in saving the lives of these patients."

The results are published in "CLYD Negatively Regulates Transforming Growth Factor- Signaling via Deubiquitinating Akt," Nature Communications, DOI: 10.1038/ncomms1776. The journal is online at www.nature.com/ncomms/index.html.

Li said the support provided by the GRA is invaluable to the groundbreaking research performed by scientists on the project. Li was named as a GRA Eminent Scholar in 2010, and Lim came to Georgia State's CIII as a GRA Distinguished Investigator in 2011. Prior to Li and Lim, Wang was named as a GRA Eminent Scholar in 2003.

"These studies are collaborative, multi-disciplinary efforts," Li said. "The support from the GRA has allowed us to build state of the art facilities at Georgia State which have been essential to making this essential life-changing research possible."


'/>"/>

Contact: Jeremy Craig
jcraig@gsu.edu
404-413-1357
Georgia State University
Source:Eurekalert

Page: 1 2

Related biology news :

1. NC State researchers get to root of parasite genome
2. Researchers find animal with ability to survive climate change
3. Researchers find an essential gene for forming ears of corn
4. Researchers note differences between people and animals on calorie restriction
5. Researchers study acoustic communication in deep-sea fish
6. Researchers discover that growing up too fast may mean dying young in honey bees
7. Researchers study how pistachios may improve heart health
8. UI researchers find potentially toxic substance present in Chicago air
9. Researchers develop new self-training gene prediction program for fungi
10. Case Western Reserve University researchers track Chernobyl fallout
11. Childrens National researchers develop novel anti-tumor vaccine
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/24/2014)... in December 2014, the 1U™ app has helped ... remember their usernames and passwords through replacing the antiquated system ... people who have struggled to remember usernames and passwords, ... on redefining identity, announced today that it is offering the ...
(Date:12/22/2014)...  The 2014 Holiday Season may be the brightest ever ... that the long anticipated floodgates for consumer biometrics may ... smart phones, tablets, and wearable mobile devices that incorporate ... users with nearly 4.8 billion biometric devices by 2020.   ...
(Date:12/19/2014)... Dec. 18, 2014  23andMe, Inc., the leading personal genetics company, ... differences in genetic ancestry of individuals from across ... arrived more than four hundred years ago, the ... for peoples from different continents. This study illuminates how American ...
Breaking Biology News(10 mins):1U Offers Best Solution to the Username / Password Dilemma: For FREE! 21U Offers Best Solution to the Username / Password Dilemma: For FREE! 3First Season of Holiday Shopping with Mobile Biometric Payments Wraps Up With a Present for Biometrics Industry: A Rosy Forecast for More Than 2 Billion Users of 4.8 Billion Mobile Biometric Devices by 2020 223andMe Study Sketches Genetic Portrait of the United States 223andMe Study Sketches Genetic Portrait of the United States 323andMe Study Sketches Genetic Portrait of the United States 4
... pioneer on synthetic biology who has engineered microbial "factories" ... drug and biofuel substitutes for gasoline, diesel and jet ... presented by the Heinz Family Foundation and carries with ... multiple titles, Keasling is the Associate Laboratory Director for ...
... research indicates marijuana-like compounds called endocannabinoids alter genes and ... placenta during pregnancy and may contribute to pregnancy complications ... edition of The Journal of Biological Chemistry ... lipid molecules produced by the body disrupts the movement ...
... A team of Australian researchers, led by University of Melbourne ... the risk of developing Autism Spectrum Disorder, ASD. Lead ... Engineering at the University of Melbourne said the test could ... "This test could assist in the early detection of ...
Cached Biology News:Jay Keasling wins Heinz Award 2Jay Keasling wins Heinz Award 3Jay Keasling wins Heinz Award 4Study implicates marijuana use in pregnancy problems 2Genetic test predicts risk for Autism 2
(Date:12/25/2014)... 2014 The report “Service Quality Management ... & Provider Type - Global Advancements, Worldwide Forecasts & ... in-depth analysis and forecasting of revenues. , Browse ... pages and in-depth TOC on “Service Quality Management (SQM) ...
(Date:12/24/2014)... Wash. , Dec. 24, 2014   BioLife Solutions , ... and marketer of proprietary clinical grade hypothermic storage ... shipping products for cells and tissues  ("BioLife" or the ... Meeting of Stockholders on May 4, 2015 (the "Annual Meeting"). ...
(Date:12/24/2014)... SoundConnect’s 2015 next ... edge communication technology, provide continued education and inform ... series demonstrates online communication features and benefits; empowering ... most innovative and powerful tools. , According to ...
(Date:12/24/2014)... 2014 Nashville Fertility Center announced that ... American Society for Reproductive Medicine (ASRM), a leading professional organization ... In his new role as treasurer, Dr. Hill also fills ... voice in furthering the mission of ASRM. , Dr. ...
Breaking Biology Technology:Service Quality Management Market worth $2.1 Billion & Telco Customer Experience Management Market worth $2.3 Billion by 2019 – New Report by MarketsandMarkets 2Service Quality Management Market worth $2.1 Billion & Telco Customer Experience Management Market worth $2.3 Billion by 2019 – New Report by MarketsandMarkets 3Service Quality Management Market worth $2.1 Billion & Telco Customer Experience Management Market worth $2.3 Billion by 2019 – New Report by MarketsandMarkets 4BioLife Solutions Sets Date for Annual Meeting of Stockholders 2SoundConnect Launches Leading Edge Business Communications Webinar Series 2SoundConnect Launches Leading Edge Business Communications Webinar Series 3Nashville Fertility Center Announces Dr. George A. Hill Selected to Serve as ASRM Treasurer for 2014-15 2Nashville Fertility Center Announces Dr. George A. Hill Selected to Serve as ASRM Treasurer for 2014-15 3
... - Covance Inc. has promoted Wendel Barr to the ... Anthony Cork to the position of president, early development, ... move supports the regional decision-making employed by its clients ... Tony have become corporate senior vice presidents and also ...
... Plan of New Jersey and announced an investment to ... Insurance Corp., Delta Dental Plan of Michigan, The Guardian ... Providers (the dental subsidiary of UnitedHealth Group). , ,These ... to enhance a platform that allows dentists to submit ...
... with innovation and excitement on its closing day, focusing ... next-generation systems designed to protect and defend the national ... email services. In addition to an array of new ... next "big thing" in a morning panel devoted to ...
Cached Biology Technology:Covance Appoints Co-Presidents for Early Development Services 2DEMO 2003 Closes with Focus on Collaboration and Communication 2DEMO 2003 Closes with Focus on Collaboration and Communication 3DEMO 2003 Closes with Focus on Collaboration and Communication 4