Navigation Links
Researchers explain a key developmental mechanism for the first time in plants
Date:3/7/2013

genome to go, and when, in order to induce this gene-repressing effect?

The key discovery by the Timmermans team, which appears online today in the journal Genes & Development, is the identification of the mechanism that brings PRC2 to specific sites along the genome precisely in those cells committed to become a leaf.

Timmermans' team showed that PRC2 physically interacts with DNA binding proteins that attach to plant DNA in specific genome regions just ahead of where the homeobox genes are situated. In the plant they studied, Arabidopsis, those DNA binding proteins are ASYMMETRIC LEAVES1 (AS1) and AS2. When a stem cell commits to becoming a leaf cell, AS1 and AS2 become active, attach at the DNA sites near BP and KNAT2, and recruit PRC2 to repress these homeobox genes. The epigenetic mark made by PRC2, which acts like a cellular memory, is heritable, and is essential in order for leaves and other plant organs to develop.

In other locations along the genome, other analogous mechanisms are surely at work, says Timmermans, whose broad interest in this research concerns its implications for patterning in development.

Timmermans is intrigued to learn the effects of tweaking with the timing of regulatory gene expression and repression. She suspects small adjustments to expression of master regulators during development are one of the means by which evolution proceeds over vast stretches of time.

She also notes that by tweaking these developmental regulatory systems, it might be possible to beneficially affect plant regeneration the process in which a new plant is generated from the leaf of an existing one. This process involves de-differentiating a mature cell and returning it to a primitive developmental state before once again allowing it to proceed down a developmental path a process akin to that employed in the making of human IPS (induced pluripotent stem) cells.


'/>"/>

Contact: Peter Tarr
tarr@cshl.edu
516-367-8455
Cold Spring Harbor Laboratory
Source:Eurekalert

Page: 1 2

Related biology news :

1. Study by UC Santa Barbara researchers suggests that bacteria communicate by touch
2. UC Santa Barbara researchers discover genetic link between visual pathways of hydras and humans
3. Researchers attempt to solve problems of antibiotic resistance and bee deaths in one
4. UNH researchers find African farmers need better climate change data to improve farming practices
5. Ottawa researchers to lead world-first clinical trial of stem cell therapy for septic shock
6. Researchers uncover molecular pathway through which common yeast becomes fungal pathogen
7. Researchers print live cells with a standard inkjet printer
8. Columbia Engineering and Penn researchers increase speed of single-molecule measurements
9. Researchers reveal how a single gene mutation leads to uncontrolled obesity
10. Researchers discover novel therapy for Crohns disease
11. New paper by Notre Dame researchers describes method for cleaning up nuclear waste
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/29/2014)... Territories in Canada and have sent smoke drifting down ... NASA,s Aqua satellite collected this natural-color image with ... 26, 2014. Actively burning areas, detected by MODIS,s thermal ... are drifting northward in this image. Smoke is ... has caused power outages in the area and because ...
(Date:7/29/2014)... from scientists at the University of Kent has shown ... are regulated a breakthrough that could have a ... from Kent,s School of Biosciences uncovered the mechanism whereby ... known as actin filaments are ,fine-tuned, to ... filaments appear to completely stable, providing a framework for ...
(Date:7/29/2014)... that brings together two of the major disciplines behind ... insect fossils through stunning photographs and unique illustrations. , ... Jepson, details the incredible preservation and diversity of fossilised ... what these remarkable fossils can tell us about the ... our planet. Like the mosquito in Jurassic Park, many ...
Breaking Biology News(10 mins):Unique images bring fossil insects back to life 2
... The naked mole rat, a curiously strange, hairless rodent, ... Scientists at The University of Texas Health Science Center San ... explore this mystery. On May 2 a Barshop Institute ... protein disposal called proteasome assemblies differ in composition ...
... UPTON, NY Hydrogen gas offers one of ... fuels. But traditional methods of producing pure hydrogen face ... releasing harmful carbon dioxide into the atmosphere or requiring ... Now, scientists at the U.S. Department of Energy,s (DOE) ...
... announced today that it is a Grand Challenges Explorations winner, ... Dr. Gregor Reid and his team are the first ... The research project will study the impact of ... on the health outcomes of pregnant women and their children. ...
Cached Biology News:Scientists find differences in naked mole rat's protein disposers 2Low-cost nanosheet catalyst discovered to split hydrogen from water 2Low-cost nanosheet catalyst discovered to split hydrogen from water 3Low-cost nanosheet catalyst discovered to split hydrogen from water 4Lawson recieves Grand Challenges Explorations grant for groundbreaking research 2
(Date:7/30/2014)... 2014 Adding to their already extensive ... special – Buy 2 of any Weighing Boats ... benefit lab technicians looking for durable and reliable weighing ... for multiple applications including weighing liquids, solid, or granulated ... including diamond-shaped, hexagonal, square, aluminum weighing, and standard boats. ...
(Date:7/29/2014)... have hurdled a number of significant technological challenges ... observing technology originally created for the James Webb ... Investigator Harvey Moseley, a scientist at NASA,s Goddard ... that electrostatically actuated microshutter arrays that is, ... are as functional as the current technology,s magnetically ...
(Date:7/29/2014)... Tough, ultralight foam of atom-thick sheets can be made ... invented at Rice University. , In microscopic images, ... with floors and walls that reinforce each other. The ... and walls of graphene oxide that self-assemble with the ... researchers say the foam could find use in structural ...
(Date:7/29/2014)... According to the new research report  "Digital ... Software), Delivery Modes (Web Based/Cloud Based) & Whole Slide ... published by MarketsandMarkets, analyzes and studies the major market ... North America , Europe , ... the World (RoW). Browse 78 market data ...
Breaking Biology Technology:Weighing Boat Promotion Now Available at Pipette.com, Major Pipette Distributor 2Revolutionary microshutter technology hurdles significant challenges 2Revolutionary microshutter technology hurdles significant challenges 3Revolutionary microshutter technology hurdles significant challenges 4Tough foam from tiny sheets 2Digital Pathology Market worth $437 Million by 2018 2Digital Pathology Market worth $437 Million by 2018 3
... In a recent report that probably went unnoticed outside ... Managers released figures that show why the rest ... a hotbed for scientific research. The numbers demonstrate that ... in labs; it's about creating jobs for the 21st ...
... Madison, Wis. - CytoDyn , a New ... Bio-Manufacturing facility to manufacture its DNA-based, pre-flu vaccine. ... Waisman Center , the biomanufacturing facility is designed ... and II human clinical trials. CytoDyn hopes to have ...
... Area Technical College would like to see more women going ... of women in IT careers has declined from a high of ... MATC. And at MATC, enrollment of women in IT programs has ... in IT Expo at the college on Wednesday was Patricia ...
Cached Biology Technology:Tapping hidden assets: Wisconsin researchers who can create jobs 2Tapping hidden assets: Wisconsin researchers who can create jobs 3Tapping hidden assets: Wisconsin researchers who can create jobs 4MATC seeks to turn around falling tech enrollment among women 2
96 Well Plate Sterile, RE bottom; consistent medium binding affinity for hydrophobic complexes and proteins....
Thermo Forma provides an array of accessory Racks for the Cryo/CryoPlus 16" Diameter storage system. To maximise inventory capacity a Jumbo Arrowhead configuration is recommended. You may choose betw...
... Console Orbital Shakers combine high durability ... programming power. The patented triple-counterbalanced ... unit to run with heavy out-of-balance ... system reduces contamination. The heavy ...
... orbital shakers combine high durability and capacity ... triple-counterbalanced heavy-duty mechanism prevents vibration, allowing the ... loads. Every other part, from the large ... thick machined aluminum platform is designed to ...
Biology Products: