Navigation Links
Researchers examine plant's ability to identify, block invading bacteria

Understanding how plants defend themselves from bacterial infections may help researchers understand how people and other animals could be better protected from such pathogens.

That's the idea behind a study to observe a specific bacteria that infects tomatoes but normally does not bother the common laboratory plant arabidopsis. Researchers hoped to understand how infection is selective in various organisms, according to a Texas AgriLife Research scientist.

Dr. Hisashi Koiwa collaborated with colleagues in Germany and Switzerland to examine the immune capabilities of different mutations of the arabidopsis plant. Their findings appeared in the Journal of Biological Chemistry.

In this study, the team was trying to figure out how a plant defends itself rather than how it gets sick, said Koiwa, who provided about 10 different lines of mutant arabidopsis plants grown in his lab at Texas A&M University.

"By learning what is wrong with a sick plant," he said, "we can study how a plant can defend itself, what mechanisms it uses for protection."

The team had to examine the plants at the cellular level where molecules are busy performing different jobs.

To understand the process, one has to examine components such as "N-glycans, receptors and ligands," Koiwa said.

The N-glycan is a polysaccharide that is critical in protein folding, a natural process which if it becomes unstable leads to various diseases, Koiwa explained. A receptor is a protein decorated with N-glycans which awaits signals from the ligands that bind and activate receptor molecules.

In viewing this mechanism across various arabidopsis plants that had been mutated to achieve different N-glycan structures, the researchers found one particular N-glycan that was critical in making sure that the receptor molecules can recognize the targeted bacteria molecule, he said.

If that polysaccharide can recognize a pathogen, it can prevent infection thus making the plant immune to that disease, the scientists noted.

"The question is fundamental. Why are we healthy in an environment of so many different bacteria?" Koiwa asked. "Why can one pathogen infect one kind of organism and not others? In this case, the same bacteria normally infects tomato plants but not arabidopsis."

Koiwa said many researchers are studying the pathway, or molecular road, that a pathogen takes on its journey to infect another organism. They want to find what "gates" exist in an organism that prevent infection with the notion that the same blocks could be adapted in a susceptible organism to prevent disease.

He said eventually using this pathway to develop new plant varieties that do not allow pathogens inside the cells would be better than breeding lines that are merely "resistant" to diseases.

"In the case of resistance, a plant has to try to fend off an infection that has been let in," Koiwa explained. "But a properly working immunity system does not let the pathogen in, so the plant does not get sick in the first place."


Contact: Kathleen Phillips
Texas A&M AgriLife Communications

Related biology news :

1. Community involvement important in fight against childhood obesity, according to UTHealth researchers
2. Exercise counters negative effects of weight regain, researchers find
3. Rice researchers make graphene hybrid
4. New dinosaur rears its head; U-M researchers part of team announcing find
5. Discovery in legumes could reduce fertilizer use, aid environment: Stanford researchers
6. Researchers fishing for cancer cure discover active DHA derivatives
7. Researchers determine how ATP, molecule bearing the fuel of life, is broken down in cells
8. NOAA, NASA and Old Dominion researchers measure impacts of changing climate on ocean biology
9. Researchers issue outlook for a significant New England red tide in 2010
10. French and Spanish researchers develop a natural alternative to antibiotics in animal feed
11. Pitt researchers report internal and environmental factors trigger unique brain activity in teens
Post Your Comments:
Related Image:
Researchers examine plant's ability to identify, block invading bacteria
(Date:5/6/2017)... , May 5, 2017 RAM ... announced a new breakthrough in biometric authentication based ... quantum mechanical properties to perform biometric authentication. These new ... semiconductor material created by Ram Group and its ... entertainment, transportation, supply chains and security. Ram Group ...
(Date:4/17/2017)... NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" or the "Company"), ... Report on Form 10-K on Thursday April 13, 2017 with the ... The ... section of the Company,s website at  under "SEC Filings," ... 2016 Year Highlights: Acquisition of ...
(Date:4/11/2017)... Research and Markets has announced the addition of the "Global ... ... at a CAGR of 30.37% during the period 2017-2021. ... based on an in-depth market analysis with inputs from industry experts. ... the coming years. The report also includes a discussion of the ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... October 12, 2017 , ... AMRI, ... and biotechnology industries to improve patient outcomes and quality of life, will now ... testing are being attributed to new regulatory requirements for all new drug products, ...
(Date:10/11/2017)... ... ... is a basic first aid supply for any work environment, but most personal eye wash ... if a dangerous substance enters both eyes? It’s one less decision, and likely quicker response ... piece. , “Whether its dirt and debris, or an acid or alkali, getting anything in ...
(Date:10/11/2017)... HILLS, Calif. , Oct. 11, 2017  SkylineDx today ... (ICR) and University of Leeds ... risk-stratify patients with multiple myeloma (MM), in a multi-centric Phase ... University of Leeds is the sponsor ... and ICR will perform the testing services to include high-risk ...
(Date:10/10/2017)... (PRWEB) , ... October 10, 2017 , ... San Diego-based ... of its corporate rebranding initiative announced today. The bold new look is part ... as the company moves into a significant growth period. , It will also expand ...
Breaking Biology Technology: