Navigation Links
Researchers examine plant's ability to identify, block invading bacteria
Date:3/3/2010

Understanding how plants defend themselves from bacterial infections may help researchers understand how people and other animals could be better protected from such pathogens.

That's the idea behind a study to observe a specific bacteria that infects tomatoes but normally does not bother the common laboratory plant arabidopsis. Researchers hoped to understand how infection is selective in various organisms, according to a Texas AgriLife Research scientist.

Dr. Hisashi Koiwa collaborated with colleagues in Germany and Switzerland to examine the immune capabilities of different mutations of the arabidopsis plant. Their findings appeared in the Journal of Biological Chemistry.

In this study, the team was trying to figure out how a plant defends itself rather than how it gets sick, said Koiwa, who provided about 10 different lines of mutant arabidopsis plants grown in his lab at Texas A&M University.

"By learning what is wrong with a sick plant," he said, "we can study how a plant can defend itself, what mechanisms it uses for protection."

The team had to examine the plants at the cellular level where molecules are busy performing different jobs.

To understand the process, one has to examine components such as "N-glycans, receptors and ligands," Koiwa said.

The N-glycan is a polysaccharide that is critical in protein folding, a natural process which if it becomes unstable leads to various diseases, Koiwa explained. A receptor is a protein decorated with N-glycans which awaits signals from the ligands that bind and activate receptor molecules.

In viewing this mechanism across various arabidopsis plants that had been mutated to achieve different N-glycan structures, the researchers found one particular N-glycan that was critical in making sure that the receptor molecules can recognize the targeted bacteria molecule, he said.

If that polysaccharide can recognize a pathogen, it can prevent infection thus making the plant immune to that disease, the scientists noted.

"The question is fundamental. Why are we healthy in an environment of so many different bacteria?" Koiwa asked. "Why can one pathogen infect one kind of organism and not others? In this case, the same bacteria normally infects tomato plants but not arabidopsis."

Koiwa said many researchers are studying the pathway, or molecular road, that a pathogen takes on its journey to infect another organism. They want to find what "gates" exist in an organism that prevent infection with the notion that the same blocks could be adapted in a susceptible organism to prevent disease.

He said eventually using this pathway to develop new plant varieties that do not allow pathogens inside the cells would be better than breeding lines that are merely "resistant" to diseases.

"In the case of resistance, a plant has to try to fend off an infection that has been let in," Koiwa explained. "But a properly working immunity system does not let the pathogen in, so the plant does not get sick in the first place."


'/>"/>

Contact: Kathleen Phillips
ka-phillips@tamu.edu
979-845-2872
Texas A&M AgriLife Communications
Source:Eurekalert  

Related biology news :

1. Community involvement important in fight against childhood obesity, according to UTHealth researchers
2. Exercise counters negative effects of weight regain, researchers find
3. Rice researchers make graphene hybrid
4. New dinosaur rears its head; U-M researchers part of team announcing find
5. Discovery in legumes could reduce fertilizer use, aid environment: Stanford researchers
6. Researchers fishing for cancer cure discover active DHA derivatives
7. Researchers determine how ATP, molecule bearing the fuel of life, is broken down in cells
8. NOAA, NASA and Old Dominion researchers measure impacts of changing climate on ocean biology
9. Researchers issue outlook for a significant New England red tide in 2010
10. French and Spanish researchers develop a natural alternative to antibiotics in animal feed
11. Pitt researchers report internal and environmental factors trigger unique brain activity in teens
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Researchers examine plant's ability to identify, block invading bacteria
(Date:12/15/2016)... 2016   WaferGen Bio-systems, Inc. (NASDAQ: ... announced today that on December 13, 2016, it received ... Nasdaq Stock Market LLC which acknowledged that, as of ... common stock had been at $1.00 or greater for ... with Listing Rule 5550(a)(2) of the Nasdaq Stock Market. ...
(Date:12/15/2016)... HILLS, Mich. , Dec. 15, 2016  There ... unlocking car doors or starting the engine. Continental will ... in Las Vegas . Through the ... (Passive Start and Entry) and biometric elements, the international ... field of vehicle personalization and authentication. "The ...
(Date:12/8/2016)... , Dec. 8, 2016 Market Research Future published a ... The global Mobile Biometric Security and Service Market is expected to ... 2022. Market Highlights: ... , Mobile Biometric Security ... to the increasing need of authentication and security from unwanted cyber ...
Breaking Biology News(10 mins):
(Date:1/19/2017)... and GAITHERSBURG, Md. , ... PIP) and Altimmune, Inc., a privately-held immunotherapeutics company ... a definitive agreement for the merger of PharmAthene ... investors include Novartis Venture Fund, HealthCap, Truffle Capital ... a fully-integrated and diversified immunotherapeutics company with four ...
(Date:1/19/2017)... ... January 18, 2017 , ... The American Medical ... update its Data Sharing Policy. Specifically, the nation’s leading informatics experts, said data ... the existing policy. AMIA recommended that NIH earmark funding for researchers to produce ...
(Date:1/19/2017)... ... January 19, 2017 , ... DaVita Clinical ... spectrum of drug and device development, and Prism Clinical Research , a ... today announced Verified Clinical Trials (VCT) has been selected by both ...
(Date:1/19/2017)... , Jan. 18, 2017 Acupath Laboratories, ... announces the formation of an Executive Committee that will ... beyond. John Cucci , a 15-year ... from Director of Business Development to Chief Sales ... Mr. Cucci served in senior sales leadership roles at ...
Breaking Biology Technology: