Navigation Links
Researchers discover workings of brain's 'GPS system'
Date:3/7/2013

Just as a global positioning system (GPS) helps find your location, the brain has an internal system for helping determine the body's location as it moves through its surroundings.

A new study from researchers at Princeton University provides evidence for how the brain performs this feat. The study, published in the journal Nature, indicates that certain position-tracking neurons called grid cells ramp their activity up and down by working together in a collective way to determine location, rather than each cell acting on its own as was proposed by a competing theory.

Grid cells are neurons that become electrically active, or "fire," as animals travel in an environment. First discovered in the mid-2000s, each cell fires when the body moves to specific locations, for example in a room. Amazingly, these locations are arranged in a hexagonal pattern like spaces on a Chinese checker board.

"Together, the grid cells form a representation of space," said David Tank, Princeton's Henry L. Hillman Professor in Molecular Biology and leader of the study. "Our research focused on the mechanisms at work in the neural system that forms these hexagonal patterns," he said. The first author on the paper was graduate student Cristina Domnisoru, who conducted the experiments together with postdoctoral researcher Amina Kinkhabwala.

Domnisoru measured the electrical signals inside individual grid cells in mouse brains while the animals traversed a computer-generated virtual environment, developed previously in the Tank lab. The animals moved on a mouse-sized treadmill while watching a video screen in a set-up that is similar to video-game virtual reality systems used by humans.

She found that the cell's electrical activity, measured as the difference in voltage between the inside and outside of the cell, started low and then ramped up, growing larger as the mouse reached each point on the hexagonal grid and then falling
'/>"/>

Contact: Catherine Zandonella
czandone@princeton.edu
Princeton University
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Study by UC Santa Barbara researchers suggests that bacteria communicate by touch
2. UC Santa Barbara researchers discover genetic link between visual pathways of hydras and humans
3. Researchers attempt to solve problems of antibiotic resistance and bee deaths in one
4. UNH researchers find African farmers need better climate change data to improve farming practices
5. Ottawa researchers to lead world-first clinical trial of stem cell therapy for septic shock
6. Researchers uncover molecular pathway through which common yeast becomes fungal pathogen
7. Researchers print live cells with a standard inkjet printer
8. Columbia Engineering and Penn researchers increase speed of single-molecule measurements
9. Researchers reveal how a single gene mutation leads to uncontrolled obesity
10. Researchers discover novel therapy for Crohns disease
11. New paper by Notre Dame researchers describes method for cleaning up nuclear waste
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Researchers discover workings of brain's 'GPS system'
(Date:3/24/2015)... WASHINGTON , March 24, 2015   NexID ... applications with critical security-authentication needs, today announced the beginning ... fake-finger-detection (FFD) solution. The company, based in ... announcement at the three-day Connect:ID Expo, which began here ... NexID said version 2.0 of its SDK boosts ...
(Date:3/23/2015)... , Mar. 23, 2015 NXT-ID, Inc. (NASDAQ: NXTD ... on the growing mobile commerce market, announces its biometric payment ... campaign on CNBC television starting March 30 th . ... airing in New York markets. ... "We are excited about our new ad campaign following the ...
(Date:3/19/2015)... , March 19, 2015  NXT-ID, Inc. (NASDAQ: ... focused on the growing mobile commerce market, announces its biometric ... news clip that aired this week on Washington ... In a segment "The Next Great Thing", host ... new way to pay, and ,a really big breakthrough in ...
Breaking Biology News(10 mins):NexID Begins Shipments Of Version 2.0 Fake-Finger-Detection Solution 2NXT-ID's Wocket Smart Wallet to Launch New CNBC Regional TV Ad Campaign 2NXT-ID's Wocket Smart Wallet to Launch New CNBC Regional TV Ad Campaign 3NXT-ID's Wocket Smart Wallet Featured on Fox News Segment, "The Next Great Thing" 2NXT-ID's Wocket Smart Wallet Featured on Fox News Segment, "The Next Great Thing" 3
... CAMBRIDGE, Mass. -- Biologists at Harvard University have identified the ... hint of orchids in the fossil record, a find they ... dinosaurs. Their analysis, published this week in the journal ... ago, much longer ago than many scientists had estimated. The ...
... could help physicians predict which lung cancer patients will ... a multidisciplinary team at the University of Cincinnati (UC). ... fundamental molecule regulates cell proliferation in the body. Research ... inactive or altered in most human cancers. Scientists are ...
... largest body of ice on Earth. Prior to approximately 10 ... the Antarctic ice sheets, which can be more than two ... too extreme. However, Brent Christner, assistant professor of biological sciences ... one of the worlds most hostile environments conducting research that ...
Cached Biology News:First orchid fossil puts showy blooms at some 80 million years old 2First orchid fossil puts showy blooms at some 80 million years old 3UC health news: molecular pathway may predict chemotherapy effectiveness 2LSU professor looks for life in and under antarctic ice 2LSU professor looks for life in and under antarctic ice 3
(Date:3/29/2015)... March 29, 2015  Caris Life Sciences® ... in small cell cervical cancer (SCCC) that ... Intelligence®, the company,s panomic, comprehensive tumor profiling ... which may explain sensitivities and resistance to ... of certain biomarkers may guide treatment strategies ...
(Date:3/29/2015)... Whitehouse, NJ (PRWEB) March 29, 2015 ... strict deadlines often required by our pharmaceutical manufacturing clients, ... renewed its sponsorship of the Berkenstock Race Team for ... track requires not only speed, but a strong sense ... same principles that lead to success in the quality ...
(Date:3/27/2015)... The consumption of compound fertilizers (NPK) ... and high prices in 2008. However, the situation has ... on gaining momentum now. , To date, the world ... 100,000 thousand tonnes. No considerable growth was registered in ... rocketed during 2012-2013, registering 11% growth as against the ...
(Date:3/27/2015)... -- Neogen Corporation (NASDAQ: NEOG ) announced today that ... in accordance with Securities and Exchange Commission rule 10b5-1. ... Corporation, is a minority owner of this entity that ... Herbert does not have control of this entity, but ... for a portion of the shares owned by that ...
Breaking Biology Technology:Study Using Caris Molecular Intelligence Multiplatform Tumor Profiling Identifies Potential Treatment Strategies for Small Cell Cervical Cancer 2Study Using Caris Molecular Intelligence Multiplatform Tumor Profiling Identifies Potential Treatment Strategies for Small Cell Cervical Cancer 3Whitehouse Laboratories Reaffirms Commitment to Speedy Results – Renews Sponsorship of Berkenstock Racing Team 2World NPK Fertilizers Market Keeps On Gaining Momentum, According to BAC Reports Study Available at MarketPublishers.com 2World NPK Fertilizers Market Keeps On Gaining Momentum, According to BAC Reports Study Available at MarketPublishers.com 3Neogen CEO adopts 10b5-1 Trading Plan 2
... HONG KONG, April 27, 2012 /PRNewswire-Asia-FirstCall/ -- China Cord Blood ... Company"), the first and largest cord blood banking operator ... a US$65 million convertible debt financing with funds affiliated ... fund managed by Kohlberg Kravis Roberts & Co. L.P. ...
... April 26, 2012  Avaxia Biologics, Inc., a privately-held biotech ... antibody therapeutics for the treatment of gastrointestinal diseases, announced ... Chief Executive Officer of Arisaph Pharmaceuticals, Inc. to its ... that Chris has agreed to serve on our Board," ...
...  Sangamo BioSciences, Inc. (Nasdaq: SGMO ) today announced ... results on Wednesday, May 2, 2012, after the market closes. ... at 5:00 p.m. ET, which will be open to the ... company will review the financial results and discuss other business ...
Cached Biology Technology:China Cord Blood Corporation Announces Completion of $65 Million Convertible Debt Financing with KKR 2China Cord Blood Corporation Announces Completion of $65 Million Convertible Debt Financing with KKR 3Avaxia Biologics Elects Christopher Kiritsy to its Board of Directors 2Sangamo BioSciences Announces First Quarter 2012 Conference Call and Webcast 2