Navigation Links
Researchers discover primer to plant defense system

OAK RIDGE, Tenn., April 3, 2009 -- By identifying a novel compound that primes a plant's immune system, researchers at Oak Ridge National Laboratory and the University of Chicago may be on a path to developing disease-resistant plants.

In a paper published in Science, a team that includes Tim Tschaplinski of the Department of Energy's ORNL reports that azelaic acid has a role in priming the immunity response in Arabidopsis, a small flowering plant related to cabbage and mustard. This plant, commonly known as thale cress or mouse-ear cress, is widely used as a model organism for studying higher plants.

While Tschaplinski acknowledged that this field is in its infancy and involves a very complex network of responses, he and co-authors are excited about what may lie ahead.

"Long term, this discovery may prove useful for preventing diseases in crops and other plants, and perhaps for generating plants that are more disease-resistant in the first place," said Tschaplinski, a member of ORNL's Environmental Sciences Division.

The discovery was actually made when Tschaplinski kept noticing a persistent mass spectral signature that occurred soon after Arabidopsis plants were exposed to a bacterial pathogen. The signal matched a pattern in a database of mass spectral signatures of Arabidopsis metabolites and prompted Tschaplinski to have a conversation with the University of Chicago's Jean Greenberg and postdoctoral scholar Ho Won Jung. Their discussion led to some additional research and this paper, titled "Priming in Systemic Plant Immunity."

Among key findings was that plants can boost their overall immunity to infection once they have a local exposure to certain pathogenic microbes. This occurs through a series of steps, beginning with a primary infection that causes the plant to induce defenses to contain the spread and growth of the pathogen. The infection causes the plant to produce more azelaic acid, which stimulates the production of AZ11, a protein that the researchers found to be essential for the increased systemic plant immunity.

Azelaic acid moves throughout the stem and leaves and bolsters the plant's immune system so it can respond quicker and more effectively to diseases compared to nave plants, according to the researchers. Through this process, plants accumulate very high levels of the defense signal salicylic acid, and this helps inhibit the progression of secondary infections.

"With respect to future science, a number of other novel signatures are clearly evident and can be pursued as a component of the plant-microbe scientific focus area if that is a route we decide to go," Tschaplinski said.

In the meantime, the authors note that, "The identification of novel systemic acquired resistance components may be useful for plant protection and provides new insight into how some interactions trigger systemic plant immunity."


Contact: Ron Walli
DOE/Oak Ridge National Laboratory

Related biology news :

1. MDC researchers prevent virus induced myocarditis
2. Researchers examine bacterial rice diseases, search for genetic solutions
3. UC Davis researchers identify a protein that may help breast cancer spread, beat cancer drugs
4. Researchers discover link between schizophrenia and diabetes
5. Cancer Genomics Browser gives cancer researchers a powerful new tool
6. Mayo Clinic researchers discover and manipulate molecular interplay that moves cancer cells
7. Two Hutchinson Center researchers named HHMI Early Career Scientists
8. Tiny but toxic: MBL researchers discover a mechanism of neurodegeneration in Alzheimers disease
9. Researchers develop flow sensors based on hair structures of blind cavefish
10. To fight drug addiction, UB researchers target the brain with nanoparticles
11. Diabetics on high-fiber diets might need extra calcium, report UT Southwestern researchers
Post Your Comments:
(Date:6/1/2016)... , June 1, 2016 ... in Election Administration and Criminal Identification to Boost Global ... a recently released TechSci Research report, " Global Biometrics ... Region, Competition Forecast and Opportunities, 2011 - 2021", the ... billion by 2021, on account of growing security concerns ...
(Date:5/9/2016)... UAE, May 9, 2016 Elevay ... comes to expanding freedom for high net worth professionals ... in today,s globally connected world, there is still no ... could ever duplicate sealing your deal with a firm ... passports by taking advantage of citizenship via investment programs ...
(Date:4/26/2016)... 2016 Research and Markets has ... Market 2016-2020"  report to their offering.  , ,     ... The analysts forecast the global multimodal biometrics market ... the period 2016-2020.  Multimodal biometrics is ... as the healthcare, BFSI, transportation, automotive, and government ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... BEACH, Calif. , June 23, 2016  Blueprint ... new biological discoveries to the medical community, has closed ... co-founder Matthew Nunez . "We have ... us with the capital we need to meet our ... will essentially provide us the runway to complete validation ...
(Date:6/23/2016)... ... June 23, 2016 , ... ... the Pennsylvania Convention Center and will showcase its product’s latest features from June ... be presenting a scientific poster on Disrupting Clinical Trials in The Cloud during ...
(Date:6/23/2016)... , June 22, 2016  Amgen (NASDAQ: ... of the QB3@953 life sciences incubator to ... health. The shared laboratory space at QB3@953 was created ... a key obstacle for many early stage organizations - ... of the sponsorship, Amgen launched two "Amgen Golden Ticket" ...
(Date:6/22/2016)... , June 22, 2016 Research and ... Global Markets" report to their offering. ... billion in 2014 from $29.3 billion in 2013. The market is ... of 13.8% from 2015 to 2020, increasing from $50.6 billion in ... projected product forecasts during the forecast period (2015 to 2020) are ...
Breaking Biology Technology: